Home| Contact Us

HOME SEARCH STATISTICS
> Protein (NX_O43295)
Protein (NX_O43295)
Protein
Gene SymbolSRGAP3 to neXtProt (NX_O43295)
DescriptionSLIT-ROBO Rho GTPase-activating protein 3
Chromosome3
Location3p25.3 (9022275 ~ 9404737) to Ensembl
Sequene Features : Isoforms 3, Variants 166, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.regulation of small GTPase mediated signal transduction
.negative regulation of cell migration
.small GTPase mediated signal transduction
.Rac GTPase binding
.GTPase activator activity
.cytosol
.cytoplasm
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
3 166 3
2014-09-19protein level
3 125 3
2014-05-27protein level
3 125 3
2014-02-25protein level
3 124 3
2013-12-09protein level
3 100 3
2013-11-01protein level
3 82 3
2013-09-12protein level
3 82 4
2013-08-17protein level
3 82 4
2013-07-15protein level
3 48 4
2013-06-11protein level
3 48 4
2013-02-12protein level
3 16 17
2012-12-20protein level
3 16 17
2012-10-30protein level
3 21 17
2012-10-07protein level
3 21 7
2012-08-24protein level
3 14 7
2012-07-28protein level
3 14 7
2012-06-08protein level
3 2 7
2012-05-07protein level
3 2 7
2012-04-10protein level
3 2 7
2012-01-13protein level
3 2 7
2011-12-20protein level
3 2 7
2011-11-11protein level
3 2 7
2011-08-23protein level
3 2 7
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_O43295-1
4 49 5 124424.9881
NX_O43295-2
1 49 5 121703.5454
NX_O43295-3
0 21 2 57190.7505
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-368166,EBI-466029 HTT  
  .negative regulation of extrinsic apoptotic signaling pathway
.iron ion homeostasis
.L-glutamate import
  + 38 more...
.diazepam binding
.beta-tubulin binding
.dynein intermediate chain binding
  + 6 more...
.protein complex
.cytoplasmic vesicle membrane
.dendrite
  + 11 more...
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
brain54
connective tissue6
embryonic tissue18
eye28
intestine8
kidney4
liver4
lung17
mammary gland6
mouth15
muscle18
nerve64
ovary9
placenta7
prostate36
skin4
testis20
thymus12
trachea38
umbilical cord72
uterus21
Health State
TissuesTPM*
normal26
breast (mammary gland) tumor10
chondrosarcoma12
germ cell tumor18
glioma37
head and neck tumor7
kidney tumor14
liver tumor10
lung tumor9
non-neoplasia10
primitive neuroectodermal tumor of the CNS7
prostate cancer57
soft tissue/muscle tissue tumor7
uterine tumor33
Developmental Stage
TissuesTPM*
adult24
embryoid body14
blastocyst16
neonate32
fetus23
juvenile17
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue1.5
adrenal gland6.7
appendix2.4
cerebral cortex21
colon2.2
duodenum1.2
esophagus2.9
gallbladder2.2
heart muscle2.7
kidney4.2
liver1.2
lung2.5
lymph node2.3
ovary6.5
placenta1.4
prostate4.9
salivary gland3.5
skin3.6
small intestine1.8
spleen1.6
stomach2.5
testis7.3
thyroid gland4.8
urinary bladder8.4
Tissues
TissuesExpression level
bronchusMedium
cerebellumMedium
cerebral cortexMedium
cervix, uterineLow
colonMedium
endometrium 1Low
endometrium 2Low
fallopian tubeMedium
heart muscleLow
kidneyLow
lateral ventricleLow
nasopharynxMedium
skeletal muscleLow
smooth muscleLow
soft tissue 1Low
urinary bladderMedium
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Expression level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*606525, gene) Slit-robo rho gtpase-activating protein 3; SRGAP3OMIM


#424, YPRC/BPRC, Industry-University Research Center, Yonsei Univ., Seodaemun-gu, Seoul, Korea, 120-749
Tel: +82-2-2123-6626, Fax: +82-2-393-6589
2014-2019 (C) Yonsei Proteome Research Center