Home| Contact Us

HOME SEARCH STATISTICS
> Protein (NX_O43299)
Protein (NX_O43299)
Protein
Gene SymbolAP5Z1 to neXtProt (NX_O43299)
DescriptionAP-5 complex subunit zeta-1
Chromosome7
Location7p22.1 (4815253 ~ 4833943) to Ensembl
Sequene Features : Isoforms 3, Variants 56, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.endosomal transport
.protein transport
.double-strand break repair via homologous recombination
.N/A .AP-5 adaptor complex
.AP-type membrane coat adaptor complex
.cytoplasm
  + 2 more...
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
3 56 3
2014-09-19protein level
3 56 3
2014-05-27protein level
3 56 3
2014-02-25protein level
3 91 3
2013-12-09protein level
3 55 3
2013-11-01protein level
3 55 3
2013-09-12protein level
3 55 3
2013-08-17protein level
3 55 3
2013-07-15protein level
3 42 1
2013-06-11protein level
3 42 1
2013-02-12protein level
3 20 0
2012-12-20protein level
3 10 0
2012-10-30protein level
3 27 0
2012-10-07protein level
3 27 0
2012-08-24protein level
3 26 0
2012-07-28protein level
3 25 0
2012-06-08protein level
3 25 0
2012-05-07protein level
3 23 0
2012-04-10protein level
3 23 0
2012-01-13protein level
3 15 0
2011-12-20protein level
3 15 0
2011-11-11protein level
3 15 0
2011-08-23protein level
3 15 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_O43299-1
10 29 0 88548.9552
NX_O43299-2
1 29 0 67410.8798
NX_O43299-3
1 19 0 48989.2618
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
ascites75
blood49
brain15
cervix20
connective tissue20
embryonic tissue14
eye28
intestine21
kidney23
liver4
lung20
lymph158
lymph node11
mammary gland6
mouth15
nerve64
ovary29
pancreas18
placenta28
salivary gland49
skin23
spleen18
stomach41
testis16
thymus12
uterus17
Health State
TissuesTPM*
normal18
breast (mammary gland) tumor10
cervical tumor28
chondrosarcoma36
colorectal tumor35
gastrointestinal tumor67
germ cell tumor26
glioma27
head and neck tumor14
kidney tumor29
leukemia31
liver tumor10
lung tumor19
lymphoma96
ovarian tumor13
pancreatic tumor38
primitive neuroectodermal tumor of the CNS62
skin tumor23
soft tissue/muscle tissue tumor15
uterine tumor11
Developmental Stage
TissuesTPM*
adult20
blastocyst32
fetus10
juvenile17
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue9.3
adrenal gland8.5
appendix13.2
bone marrow12
cerebral cortex5.5
colon7.8
duodenum12.2
esophagus3.7
gallbladder6.3
heart muscle3.6
kidney7.6
liver2.8
lung8.9
lymph node15.1
ovary5.6
pancreas5
placenta6.4
prostate9.5
salivary gland8.3
skin17.4
small intestine10.5
spleen19.1
stomach12.6
testis9.2
thyroid gland4.9
urinary bladder6
Tissues
TissuesExpression level
adrenal glandHigh
appendixMedium
bone marrowLow
bronchusMedium
cerebellumHigh
cerebral cortexHigh
cervix, uterineHigh
colonHigh
duodenumHigh
endometrium 1High
endometrium 2Medium
epididymisHigh
esophagusHigh
fallopian tubeHigh
heart muscleMedium
hippocampusMedium
kidneyHigh
lateral ventricleHigh
liverMedium
lungMedium
lymph nodeMedium
nasopharynxHigh
oral mucosaHigh
pancreasHigh
parathyroid glandHigh
placentaHigh
prostateHigh
rectumHigh
salivary glandMedium
seminal vesicleMedium
skeletal muscleMedium
skin 1Medium
skin 2High
small intestineHigh
smooth muscleMedium
soft tissue 1Low
soft tissue 2Medium
spleenMedium
stomach 1High
stomach 2High
testisMedium
thyroid glandMedium
tonsilHigh
urinary bladderMedium
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Expression level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(#613647, phenotype) Spastic paraplegia 48, autosomal recessive; SPG48OMIM
2(*613653, gene) Adaptor-related protein complex 5, zeta-1 subunit; AP5Z1OMIM


#424, YPRC/BPRC, Industry-University Research Center, Yonsei Univ., Seodaemun-gu, Seoul, Korea, 120-749
Tel: +82-2-2123-6626, Fax: +82-2-393-6589
2014-2019 (C) Yonsei Proteome Research Center