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> Protein (NX_O43303)
Protein (NX_O43303)
Protein
Gene SymbolCCP110 to neXtProt (NX_O43303)
DescriptionCentriolar coiled-coil protein of 110 kDa
Chromosome16
Location16p12.3 (19535133 ~ 19564730) to Ensembl
Sequene Features : Isoforms 2, Variants 87, PTMs 11 to neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.centrosome duplication
.regulation of cytokinesis
.cell projection organization
  + 4 more...
.N/A .protein complex
.cytosol
.centriole
.centrosome
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
2 87 11
2014-09-19protein level
2 70 11
2014-05-27protein level
2 68 11
2014-02-25protein level
2 68 12
2013-12-09protein level
2 48 12
2013-11-01protein level
2 46 12
2013-09-12protein level
2 46 12
2013-08-17protein level
2 46 12
2013-07-15protein level
2 27 7
2013-06-11protein level
2 27 7
2013-02-12protein level
2 13 8
2012-12-20protein level
2 12 8
2012-10-30protein level
2 19 8
2012-10-07protein level
2 19 4
2012-08-24protein level
2 19 4
2012-07-28protein level
2 19 4
2012-06-08protein level
2 21 4
2012-05-07protein level
2 21 4
2012-04-10protein level
2 21 4
2012-01-13protein level
2 14 4
2011-12-20protein level
2 14 4
2011-11-11protein level
2 14 4
2011-08-23protein level
2 14 4
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_O43303-1
1 43 0 113352.4071
NX_O43303-2
0 43 0 111153.0241
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-1566217,EBI-1207574 CCNF  
  .cell division
.SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
.protein ubiquitination
  + 4 more...
.N/A .SCF ubiquitin ligase complex
.centriole
.nucleus
2 EBI-1566217,EBI-1789926 CETN2  
  .cell division
.cellular protein metabolic process
.post-translational protein modification
  + 9 more...
.calcium ion binding .XPC complex
.ciliary basal body
.photoreceptor connecting cilium
  + 5 more...
3 EBI-1566217,EBI-397435 CALM2  
  .regulation of cell communication by electrical coupling involved in cardiac conduction
.regulation of high voltage-gated calcium channel activity
.positive regulation of protein serine/threonine kinase activity
  + 48 more...
.protein phosphatase activator activity
.ion channel binding
.protein serine/threonine kinase activator activity
  + 8 more...
.extracellular exosome
.vesicle
.growth cone
  + 10 more...
4 EBI-1566217,EBI-2556811 KIF24  
  .cilium assembly
.metabolic process
.microtubule depolymerization
  + 2 more...
.ATPase activity
.ATP binding
.microtubule motor activity
.protein complex
.microtubule
.kinesin complex
  + 2 more...
5 EBI-1566217,EBI-1566210 CEP97  
  .cell projection organization
.organelle organization
.N/A .protein complex
.cytosol
.microtubule organizing center
  + 2 more...
6 EBI-1566217,EBI-1053406 NEURL4  
  .N/A .N/A .centriole
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
bladder33
blood16
bone marrow20
brain99
ear124
embryonic tissue51
esophagus49
eye23
intestine8
kidney33
liver34
lung32
lymph node11
mammary gland72
mouth45
muscle75
nerve64
ovary19
pancreas37
pituitary gland121
placenta10
prostate21
skin9
spleen18
testis59
thymus87
trachea96
uterus25
vascular38
Health State
TissuesTPM*
normal47
bladder carcinoma56
breast (mammary gland) tumor85
germ cell tumor22
glioma18
head and neck tumor22
kidney tumor43
leukemia31
liver tumor10
lung tumor9
non-neoplasia62
ovarian tumor26
primitive neuroectodermal tumor of the CNS7
prostate cancer38
retinoblastoma43
skin tumor15
soft tissue/muscle tissue tumor23
uterine tumor22
Developmental Stage
TissuesTPM*
adult29
embryoid body57
blastocyst81
fetus35
juvenile53
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue6
adrenal gland8.6
appendix9.7
bone marrow12.7
cerebral cortex23.4
colon6.7
duodenum6.1
esophagus8.7
gallbladder8.5
heart muscle4.3
kidney6
liver2.6
lung11.5
lymph node10.2
ovary13.4
pancreas2.2
placenta5.6
prostate10
salivary gland4.1
skin7.9
small intestine6.3
spleen7.9
stomach8.9
testis39.8
thyroid gland9.4
urinary bladder8.2
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*609544, gene) Centrosomal protein, 110-kdOMIM


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