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> Protein (NX_O43309)
Protein (NX_O43309)
Protein
Gene SymbolZSCAN12 to neXtProt (NX_O43309)
DescriptionZinc finger and SCAN domain-containing protein 12
Chromosome6
Location6p22.1 (28346732 ~ 28367511) to Ensembl
Sequene Features : Isoforms 1, Variants 51, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.transcription, DNA-templated .metal ion binding
.sequence-specific DNA binding transcription factor activity
.DNA binding
.nucleus
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 51 0
2014-09-19protein level
1 40 0
2014-05-27transcript level
1 40 0
2014-02-25transcript level
1 39 0
2013-12-09transcript level
1 31 0
2013-11-01transcript level
1 29 0
2013-09-12transcript level
1 29 0
2013-08-17transcript level
1 29 0
2013-07-15transcript level
1 16 0
2013-06-11transcript level
1 16 0
2013-02-12transcript level
1 8 0
2012-12-20transcript level
1 12 0
2012-10-30transcript level
1 12 0
2012-10-07transcript level
1 12 0
2012-08-24transcript level
1 11 0
2012-07-28transcript level
1 11 0
2012-06-08transcript level
1 11 0
2012-05-07transcript level
1 11 0
2012-04-10transcript level
1 11 0
2012-01-13transcript level
1 10 0
2011-12-20transcript level
1 10 0
2011-11-11transcript level
1 10 0
2011-08-23transcript level
1 10 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_O43309-1
24 0 6 70177.5949
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-1210440,EBI-742948 MTUS2  
  .N/A .protein homodimerization activity
.microtubule binding
.microtubule
.cytoplasm
.nucleus
2 EBI-1210440,EBI-739624 CEP70  
  .organelle organization
.mitotic cell cycle
.G2/M transition of mitotic cell cycle
.N/A .nuclear membrane
.cytosol
.centrosome
  + 2 more...
3 EBI-1210440,EBI-751409 ZNF473  
  .mRNA 3'-end processing
.gene expression
.histone mRNA metabolic process
  + 4 more...
.metal ion binding
.DNA binding
.Cajal body
.nucleoplasm
4 EBI-1210440,EBI-743906 ZNF496  
  .positive regulation of transcription, DNA-templated
.transcription from RNA polymerase II promoter
.negative regulation of transcription from RNA polymerase II promoter
.metal ion binding
.DNA binding
.sequence-specific DNA binding RNA polymerase II transcription factor activity
.nuclear body
.nucleus
5 EBI-1210440,EBI-743851 ZKSCAN7  
  .transcription, DNA-templated .metal ion binding
.sequence-specific DNA binding transcription factor activity
.DNA binding
.nucleus
6 EBI-1210440,EBI-1105213 TFIP11  
  .biomineral tissue development
.RNA processing
.regulation of transcription, DNA-templated
  + 2 more...
.DNA binding .catalytic step 2 spliceosome
.U2-type post-mRNA release spliceosomal complex
.nuclear speck
  + 3 more...
7 EBI-1210440,EBI-10172526 MID2  
  .negative regulation of viral release from host cell
.positive regulation of NF-kappaB transcription factor activity
.positive regulation of sequence-specific DNA binding transcription factor activity
  + 6 more...
.phosphoprotein binding
.protein heterodimerization activity
.protein homodimerization activity
  + 3 more...
.extracellular exosome
.microtubule
.cytoplasm
8 EBI-1210440,EBI-2212028 SSX2IP  
  .regulation of cell motility
.centrosome organization
.cilium assembly
  + 3 more...
.N/A .protein complex
.ciliary basal body
.centriolar satellite
  + 3 more...
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
brain9
ear62
embryonic tissue37
esophagus49
heart11
intestine4
kidney4
larynx298
liver4
lung8
lymph node11
mammary gland6
mouth15
muscle28
ovary9
placenta10
prostate5
skin18
testis25
thymus12
thyroid21
Health State
TissuesTPM*
normal10
breast (mammary gland) tumor10
colorectal tumor8
esophageal tumor57
germ cell tumor7
glioma27
head and neck tumor67
lung tumor19
ovarian tumor13
primitive neuroectodermal tumor of the CNS23
skin tumor31
Developmental Stage
TissuesTPM*
adult13
embryoid body42
fetus14
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue1.7
adrenal gland2.5
appendix2.7
bone marrow1.2
cerebral cortex2.9
colon2.2
duodenum2.4
esophagus1.8
gallbladder2.5
heart muscle1.8
kidney2.4
lung2.8
lymph node4.3
ovary5
pancreas1.6
placenta2.7
prostate4.1
salivary gland2.1
skin1.4
small intestine2.5
spleen3.5
stomach2.5
testis4.2
thyroid gland4.9
urinary bladder3.5
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*603978, gene) Zinc finger- and scan domain-containing protein 12; ZSCAN12OMIM


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