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> Protein (NX_O43310)
Protein (NX_O43310)
Protein
Gene SymbolCTIF to neXtProt (NX_O43310)
DescriptionCBP80/20-dependent translation initiation factor
Chromosome18
Location18q21.1 (46065417 ~ 46389588) to Ensembl
Sequene Features : Isoforms 2, Variants 87, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.regulation of translational initiation
.nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
.RNA binding .perinuclear region of cytoplasm
.cytoplasm
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
2 87 3
2014-09-19protein level
2 62 3
2014-05-27protein level
2 62 3
2014-02-25protein level
2 61 3
2013-12-09protein level
2 47 3
2013-11-01protein level
2 46 3
2013-09-12protein level
2 46 3
2013-08-17protein level
2 46 3
2013-07-15protein level
2 33 2
2013-06-11protein level
2 33 2
2013-02-12protein level
2 20 8
2012-12-20protein level
2 20 8
2012-10-30protein level
2 22 8
2012-10-07protein level
2 22 4
2012-08-24protein level
2 19 4
2012-07-28protein level
2 19 4
2012-06-08protein level
2 20 4
2012-05-07protein level
2 12 4
2012-04-10protein level
3 3 4
2012-01-13protein level
3 3 4
2011-12-20protein level
3 3 4
2011-11-11protein level
3 3 4
2011-08-23protein level
3 3 4
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_O43310-1
1 33 0 67544.204
NX_O43310-2
1 33 0 67740.3246
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adipose tissue233
adrenal gland30
blood40
bone13
brain36
connective tissue13
embryonic tissue46
eye67
intestine17
kidney18
larynx42
liver9
lung50
mammary gland13
nerve193
ovary29
pancreas9
pituitary gland60
prostate10
skin23
spleen18
testis13
thyroid21
uterus8
Health State
TissuesTPM*
normal27
adrenal tumor79
breast (mammary gland) tumor21
chondrosarcoma36
colorectal tumor26
germ cell tumor7
glioma55
head and neck tumor14
kidney tumor29
leukemia21
liver tumor10
lung tumor87
non-neoplasia41
pancreatic tumor9
primitive neuroectodermal tumor of the CNS7
prostate cancer9
retinoblastoma43
soft tissue/muscle tissue tumor15
Developmental Stage
TissuesTPM*
adult23
embryoid body57
blastocyst65
fetus32
juvenile53
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue42.5
adrenal gland16.7
appendix8.5
bone marrow2.9
cerebral cortex27.5
colon6.6
duodenum6.6
esophagus29.7
gallbladder32.7
heart muscle21.6
kidney10.5
liver5.5
lung16.5
lymph node4.7
ovary34.3
pancreas4.5
placenta10.5
prostate10
salivary gland12.1
skin5.8
small intestine6.2
spleen6.7
stomach8.8
testis13.5
thyroid gland16.4
urinary bladder19.4
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*613178, gene) Kiaa0427 gene; KIAA0427OMIM


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