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> Protein (NX_O43312)
Protein (NX_O43312)
Protein
Gene SymbolMTSS1 to neXtProt (NX_O43312)
DescriptionMetastasis suppressor protein 1
Chromosome8
Location8q24.13 (125563031 ~ 125740730) to Ensembl
Sequene Features : Isoforms 4, Variants 97, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.epithelial cell proliferation involved in renal tubule morphogenesis
.nephron tubule epithelial cell differentiation
.glomerulus morphogenesis
  + 16 more...
.identical protein binding
.receptor binding
.actin monomer binding
.endocytic vesicle
.actin cytoskeleton
.adherens junction
  + 2 more...
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
4 97 5
2014-09-19protein level
4 76 5
2014-05-27protein level
4 76 5
2014-02-25protein level
3 76 5
2013-12-09protein level
3 54 5
2013-11-01protein level
3 51 5
2013-09-12protein level
3 51 9
2013-08-17protein level
3 51 9
2013-07-15protein level
3 39 9
2013-06-11protein level
3 39 9
2013-02-12protein level
3 14 24
2012-12-20protein level
3 15 24
2012-10-30protein level
3 20 24
2012-10-07protein level
3 20 8
2012-08-24protein level
3 15 8
2012-07-28protein level
3 15 8
2012-06-08protein level
3 18 8
2012-05-07protein level
3 18 8
2012-04-10protein level
3 18 8
2012-01-13protein level
3 7 8
2011-12-20protein level
3 7 8
2011-11-11protein level
3 7 8
2011-08-23protein level
3 7 8
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_O43312-1
0 31 1 82199.6356
NX_O43312-2
2 20 0 50618.5121
NX_O43312-4
1 29 1 79094.7954
NX_O43312-5
0 31 1 82627.8615
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-473954,EBI-466029 HTT  
  .negative regulation of extrinsic apoptotic signaling pathway
.iron ion homeostasis
.L-glutamate import
  + 38 more...
.diazepam binding
.beta-tubulin binding
.dynein intermediate chain binding
  + 6 more...
.protein complex
.cytoplasmic vesicle membrane
.dendrite
  + 11 more...
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adrenal gland91
bladder66
blood16
brain101
connective tissue20
embryonic tissue9
eye67
heart111
intestine12
kidney4
larynx170
liver63
lung5
lymph node33
mammary gland6
mouth256
muscle28
nerve128
ovary29
pancreas74
pharynx24
placenta56
prostate26
skin33
spleen112
testis85
thymus50
thyroid21
trachea57
uterus12
Health State
TissuesTPM*
normal1
adrenal tumor158
breast (mammary gland) tumor10
chondrosarcoma12
colorectal tumor17
germ cell tumor18
glioma111
head and neck tumor7
kidney tumor58
leukemia10
liver tumor83
lung tumor19
non-neoplasia62
ovarian tumor39
pancreatic tumor38
primitive neuroectodermal tumor of the CNS55
prostate cancer9
soft tissue/muscle tissue tumor7
uterine tumor11
Developmental Stage
TissuesTPM*
adult1
embryoid body28
fetus91
infant42
juvenile53
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue25.5
adrenal gland42.8
appendix15.8
bone marrow24
cerebral cortex23.7
colon12.1
duodenum6.2
esophagus76.2
gallbladder26.3
heart muscle16.2
kidney28.4
liver51.1
lung24
lymph node24.1
ovary11.4
pancreas15.7
placenta35.7
prostate11.8
salivary gland12.8
skin46.2
small intestine5.7
spleen43.8
stomach14.8
testis31.3
thyroid gland11.3
urinary bladder23.5
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Disease
No.Disease DescriptionRef.
1(*608486, gene) Metastasis suppressor 1; MTSS1OMIM


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