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> Protein (NX_O43313)
Protein (NX_O43313)
Protein
Gene SymbolATMIN to neXtProt (NX_O43313)
DescriptionATM interactor
Chromosome16
Location16q23.2 (81069452 ~ 81080963) to Ensembl
Sequene Features : Isoforms 2, Variants 90, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.positive regulation of transcription, DNA-templated
.cellular response to DNA damage stimulus
.transcription, DNA-templated
.metal ion binding
.dynein binding
.transcription regulatory region DNA binding
.nucleus
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
2 90 0
2014-09-19protein level
2 72 0
2014-05-27protein level
2 72 0
2014-02-25protein level
2 71 0
2013-12-09protein level
2 52 0
2013-11-01protein level
2 50 0
2013-09-12protein level
2 50 0
2013-08-17protein level
2 50 0
2013-07-15protein level
2 37 0
2013-06-11protein level
2 37 0
2013-02-12protein level
2 18 0
2012-12-20protein level
2 18 0
2012-10-30protein level
2 23 0
2012-10-07protein level
2 23 0
2012-08-24protein level
2 22 0
2012-07-28protein level
2 22 0
2012-06-08protein level
2 30 0
2012-05-07protein level
2 29 0
2012-04-10protein level
2 29 0
2012-01-13protein level
2 18 0
2011-12-20protein level
2 18 0
2011-11-11protein level
2 18 0
2011-08-23protein level
2 18 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_O43313-1
8 21 0 88291.9219
NX_O43313-2
0 21 0 72288.5873
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-7422202,EBI-495465 ATM  
  .regulation of cellular response to heat
.replicative senescence
.signal transduction involved in mitotic G2 DNA damage checkpoint
  + 33 more...
.protein N-terminus binding
.protein dimerization activity
.histone serine kinase activity
  + 6 more...
.cytoplasmic membrane-bounded vesicle
.spindle
.nucleoplasm
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adrenal gland121
ascites125
bladder33
blood24
bone13
bone marrow41
brain43
cervix144
connective tissue53
ear62
embryonic tissue37
esophagus49
eye71
heart89
intestine47
kidney85
larynx127
liver29
lung83
lymph node167
mammary gland52
mouth30
muscle47
nerve128
ovary39
pancreas70
parathyroid194
pharynx49
pituitary gland60
placenta63
prostate79
skin37
spleen56
stomach52
testis80
thymus25
thyroid21
uterus150
vascular38
Health State
TissuesTPM*
normal62
adrenal tumor158
bladder carcinoma56
breast (mammary gland) tumor21
cervical tumor202
chondrosarcoma84
colorectal tumor17
esophageal tumor57
gastrointestinal tumor151
germ cell tumor79
glioma27
head and neck tumor52
kidney tumor72
leukemia52
liver tumor52
lung tumor58
lymphoma13
non-neoplasia62
ovarian tumor52
pancreatic tumor104
primitive neuroectodermal tumor of the CNS55
prostate cancer86
skin tumor31
soft tissue/muscle tissue tumor63
uterine tumor321
Developmental Stage
TissuesTPM*
adult69
embryoid body42
blastocyst16
fetus66
juvenile53
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue19.4
adrenal gland16.3
appendix16.2
bone marrow14.7
cerebral cortex25.6
colon19.8
duodenum16.6
esophagus28.4
gallbladder17.5
heart muscle17.7
kidney19.8
liver10.5
lung15
lymph node18.6
ovary22.8
pancreas9.7
placenta35.4
prostate20.7
salivary gland13.1
skin21.9
small intestine17.4
spleen15.5
stomach15
testis51.1
thyroid gland27.9
urinary bladder24.6
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*614693, gene) Atm interactor; ATMINOMIM


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