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> Protein (NX_O43365)
Protein (NX_O43365)
Protein
Gene SymbolHOXA3 to neXtProt (NX_O43365)
DescriptionHomeobox protein Hox-A3
Chromosome7
Location7p15.2 (27145803 ~ 27192200) to Ensembl
Sequene Features : Isoforms 1, Variants 71, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.parathyroid gland development
.cartilage development
.embryonic skeletal system morphogenesis
  + 10 more...
.sequence-specific DNA binding
.sequence-specific DNA binding transcription factor activity
.nucleoplasm
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01transcript level
1 71 0
2014-09-19transcript level
1 46 0
2014-05-27transcript level
1 46 0
2014-02-25transcript level
1 46 0
2013-12-09transcript level
1 38 0
2013-11-01transcript level
1 36 0
2013-09-12transcript level
1 36 0
2013-08-17transcript level
1 36 0
2013-07-15transcript level
1 27 0
2013-06-11transcript level
1 27 0
2013-02-12transcript level
1 7 0
2012-12-20transcript level
1 7 0
2012-10-30transcript level
1 8 0
2012-10-07transcript level
1 8 0
2012-08-24transcript level
1 6 0
2012-07-28transcript level
1 6 0
2012-06-08transcript level
1 6 0
2012-05-07transcript level
1 6 0
2012-04-10transcript level
1 6 0
2012-01-13transcript level
1 4 0
2011-12-20transcript level
1 4 0
2011-11-11transcript level
1 4 0
2011-08-23transcript level
1 4 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_O43365-1
9 0 2 46339.5501
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-8643838,EBI-351829 ARPC3  
  .ephrin receptor signaling pathway
.innate immune response
.Fc-gamma receptor signaling pathway involved in phagocytosis
  + 4 more...
.structural constituent of cytoskeleton .extracellular exosome
.lamellipodium
.membrane
  + 4 more...
2 EBI-8643838,EBI-742673 SEC23B  
  .vesicle-mediated transport
.ER to Golgi vesicle-mediated transport
.intracellular protein transport
.zinc ion binding .perinuclear region of cytoplasm
.intracellular membrane-bounded organelle
.endoplasmic reticulum-Golgi intermediate compartment membrane
  + 5 more...
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
ascites25
intestine12
kidney18
liver4
lung14
mammary gland6
ovary9
pituitary gland60
prostate5
testis25
uterus8
vascular38
Health State
TissuesTPM*
normal3
breast (mammary gland) tumor10
colorectal tumor26
gastrointestinal tumor8
germ cell tumor41
glioma9
head and neck tumor7
liver tumor10
ovarian tumor13
soft tissue/muscle tissue tumor7
uterine tumor11
Developmental Stage
TissuesTPM*
adult10
fetus3
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue4.8
adrenal gland1.5
appendix2.5
colon6.6
duodenum1.4
esophagus2.1
kidney6.4
lung4.1
lymph node1.1
ovary1.2
prostate5.4
skin2.2
small intestine4
spleen1.1
stomach2.4
testis1.6
urinary bladder2.6
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*142954, gene) Homeobox a3; HOXA3OMIM


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