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> Protein (NX_O43396)
Protein (NX_O43396)
Protein
Gene SymbolTXNL1 to neXtProt (NX_O43396)
DescriptionThioredoxin-like protein 1
Chromosome18
Location18q21.31 (54264439 ~ 54318831) to Ensembl
Sequene Features : Isoforms 1, Variants 31, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.oxidation-reduction process
.cell redox homeostasis
.cellular response to oxidative stress
  + 3 more...
.oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor
.disulfide oxidoreductase activity
.protein disulfide oxidoreductase activity
.extracellular exosome
.cytoplasm
.nucleus
.proteasome complex
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 31 8
2014-09-19protein level
1 23 8
2014-05-27protein level
1 23 8
2014-02-25protein level
1 23 8
2013-12-09protein level
1 19 8
2013-11-01protein level
1 18 8
2013-09-12protein level
1 18 8
2013-08-17protein level
1 18 8
2013-07-15protein level
1 10 2
2013-06-11protein level
1 10 2
2013-02-12protein level
1 1 2
2012-12-20protein level
1 2 2
2012-10-30protein level
1 3 2
2012-10-07protein level
1 3 2
2012-08-24protein level
1 3 2
2012-07-28protein level
1 3 2
2012-06-08protein level
1 3 2
2012-05-07protein level
1 3 2
2012-04-10protein level
1 3 2
2012-01-13protein level
1 3 2
2011-12-20protein level
1 3 2
2011-11-11protein level
1 3 2
2011-08-23protein level
1 3 2
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_O43396-1
14 0 0 32230.6387
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adipose tissue77
adrenal gland91
ascites50
bladder133
blood73
bone55
bone marrow102
brain62
cervix103
connective tissue80
embryonic tissue112
esophagus99
eye62
heart100
intestine51
kidney113
liver73
lung74
lymph22
lymph node66
mammary gland33
mouth75
muscle84
nerve64
ovary88
pancreas46
parathyroid194
pituitary gland60
placenta42
prostate84
salivary gland49
skin71
spleen18
stomach10
testis39
thymus12
thyroid42
umbilical cord217
uterus129
vascular135
Health State
TissuesTPM*
normal65
adrenal tumor79
bladder carcinoma341
breast (mammary gland) tumor42
cervical tumor86
chondrosarcoma36
colorectal tumor44
esophageal tumor115
gastrointestinal tumor33
germ cell tumor34
glioma93
head and neck tumor37
kidney tumor87
leukemia63
liver tumor93
lung tumor38
lymphoma27
non-neoplasia93
ovarian tumor91
pancreatic tumor47
primitive neuroectodermal tumor of the CNS62
prostate cancer77
retinoblastoma43
skin tumor63
soft tissue/muscle tissue tumor215
uterine tumor99
Developmental Stage
TissuesTPM*
adult61
embryoid body200
blastocyst48
neonate96
fetus82
infant85
juvenile89
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue31.4
adrenal gland50.9
appendix39.8
bone marrow42.8
cerebral cortex38.6
colon42.4
duodenum42.6
esophagus51.9
gallbladder42.3
heart muscle46.8
kidney41.2
liver37.9
lung28.9
lymph node41
ovary44.2
pancreas32
placenta44.5
prostate40.2
salivary gland36.6
skin28.3
small intestine39.2
spleen28.4
stomach40.7
testis44.3
thyroid gland191.7
urinary bladder51.6
Tissues
TissuesExpression level
adrenal glandMedium
appendixMedium
bone marrowMedium
breastMedium
bronchusMedium
cerebellumHigh
cerebral cortexHigh
cervix, uterineMedium
colonMedium
duodenumMedium
endometrium 1Medium
endometrium 2Low
epididymisHigh
esophagusMedium
fallopian tubeMedium
gallbladderMedium
heart muscleLow
hippocampusHigh
kidneyMedium
lateral ventricleHigh
liverLow
lungMedium
lymph nodeLow
nasopharynxMedium
oral mucosaMedium
ovaryMedium
pancreasMedium
parathyroid glandLow
placentaMedium
prostateMedium
rectumMedium
salivary glandMedium
seminal vesicleMedium
skeletal muscleLow
skin 1Medium
skin 2Low
small intestineMedium
smooth muscleLow
soft tissue 1Medium
soft tissue 2Low
spleenLow
stomach 1High
stomach 2High
testisMedium
thyroid glandHigh
tonsilMedium
urinary bladderMedium
vaginaLow
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Expression level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*603049, gene) Thioredoxin-like 1; TXNL1OMIM


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