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> Protein (NX_O43402)
Protein (NX_O43402)
Protein
Gene SymbolEMC8 to neXtProt (NX_O43402)
DescriptionER membrane protein complex subunit 8
Chromosome16
Location16q24.1 (85805364 ~ 85833214) to Ensembl
Sequene Features : Isoforms 2, Variants 7, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.N/A .N/A .ER membrane protein complex
.membrane
.mitochondrion
  + 2 more...
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
2 7 3
2014-09-19protein level
2 11 3
2014-05-27protein level
2 11 3
2014-02-25protein level
2 11 3
2013-12-09protein level
2 8 3
2013-11-01protein level
2 8 3
2013-09-12protein level
2 8 3
2013-08-17protein level
2 8 3
2013-07-15protein level
2 5 1
2013-06-11protein level
2 5 1
2013-02-12protein level
2 5 2
2012-12-20protein level
1 5 1
2012-10-30protein level
1 4 1
2012-10-07protein level
1 4 1
2012-08-24protein level
1 3 1
2012-07-28protein level
1 3 1
2012-06-08protein level
1 3 1
2012-05-07protein level
1 3 1
2012-04-10protein level
1 3 1
2012-01-13protein level
1 6 1
2011-12-20protein level
1 6 1
2011-11-11protein level
1 6 1
2011-08-23protein level
1 6 1
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_O43402-1
6 5 0 23757.595
NX_O43402-2
1 5 0 13716.9948
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adrenal gland91
ascites50
bladder33
blood32
bone83
bone marrow41
brain50
cervix82
connective tissue20
embryonic tissue51
esophagus49
eye110
heart100
intestine81
kidney71
liver34
lung119
lymph112
lymph node122
mammary gland72
mouth15
muscle37
ovary98
pancreas70
pituitary gland60
placenta88
prostate158
salivary gland296
skin113
spleen37
testis66
thymus12
tonsil117
umbilical cord217
uterus116
vascular19
Health State
TissuesTPM*
normal45
bladder carcinoma56
breast (mammary gland) tumor53
cervical tumor86
chondrosarcoma96
colorectal tumor62
esophageal tumor57
gastrointestinal tumor16
germ cell tumor129
glioma242
head and neck tumor52
kidney tumor58
leukemia63
liver tumor41
lung tumor29
lymphoma110
non-neoplasia20
ovarian tumor131
pancreatic tumor123
primitive neuroectodermal tumor of the CNS133
prostate cancer202
retinoblastoma193
skin tumor175
soft tissue/muscle tissue tumor119
uterine tumor110
Developmental Stage
TissuesTPM*
adult64
embryoid body85
blastocyst32
neonate96
fetus71
juvenile35
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue10.3
adrenal gland10.1
appendix11.2
bone marrow15.3
cerebral cortex9.4
colon11.8
duodenum10.9
esophagus8.3
gallbladder8.6
heart muscle11.3
kidney9.9
liver6.1
lung8.8
lymph node11.6
ovary7.2
pancreas5.1
placenta11.7
prostate10.6
salivary gland7.1
skin7.8
small intestine8.2
spleen12.3
stomach10.1
testis13.5
thyroid gland10.4
urinary bladder11.3
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*604886, gene) Cox4, neighbor of; NOC4OMIM


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