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> Protein (NX_O43482)
Protein (NX_O43482)
Protein
Gene SymbolOIP5 to neXtProt (NX_O43482)
DescriptionProtein Mis18-beta
Chromosome15
Location15q15.1 (41601466 ~ 41624819) to Ensembl
Sequene Features : Isoforms 1, Variants 28, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.cell division
.CENP-A containing nucleosome assembly
.cell communication
  + 2 more...
.N/A .Cajal body
.chromocenter
.cytoplasm
  + 4 more...
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 28 5
2014-09-19protein level
1 25 5
2014-05-27protein level
1 25 5
2014-02-25protein level
1 25 5
2013-12-09protein level
1 14 5
2013-11-01protein level
1 14 5
2013-09-12protein level
1 14 5
2013-08-17protein level
1 14 5
2013-07-15protein level
1 11 3
2013-06-11protein level
1 11 3
2013-02-12protein level
1 6 3
2012-12-20protein level
1 5 3
2012-10-30protein level
1 9 3
2012-10-07protein level
1 9 3
2012-08-24protein level
1 9 3
2012-07-28protein level
1 9 3
2012-06-08protein level
1 9 3
2012-05-07protein level
1 9 3
2012-04-10protein level
1 9 3
2012-01-13protein level
1 5 3
2011-12-20protein level
1 5 3
2011-11-11protein level
1 5 3
2011-08-23protein level
1 5 3
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_O43482-1
10 0 0 24675.4197
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-536879,EBI-365996 RAF1  
  .regulation of cell motility
.negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
.death-inducing signaling complex assembly
  + 36 more...
.metal ion binding
.identical protein binding
.ATP binding
  + 3 more...
.pseudopodium
.plasma membrane
.cytosol
  + 4 more...
2 EBI-536879,EBI-355607 TPM3  
  .muscle filament sliding
.muscle contraction
.movement of cell or subcellular component
.N/A .extracellular exosome
.muscle thin filament tropomyosin
.cytoskeleton
  + 2 more...
3 EBI-536879,EBI-2902468 SKIL  
  .positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage
.positive regulation of extrinsic apoptotic signaling pathway via death domain receptors
.response to growth factor
  + 19 more...
.SMAD binding
.protein complex binding
.protein domain specific binding
  + 4 more...
.protein complex
.PML body
.cytoplasm
  + 3 more...
4 EBI-536879,EBI-739566 KRT15  
  .activation of mitophagy in response to mitochondrial depolarization
.epidermis development
.scaffold protein binding
.structural constituent of cytoskeleton
.extracellular exosome
.intermediate filament
.nucleus
5 EBI-536879,EBI-347978 NUP62  
  .regulation of cellular response to heat
.transmembrane transport
.mRNA transport
  + 34 more...
.thyroid hormone receptor binding
.ubiquitin binding
.SH2 domain binding
  + 3 more...
.Flemming body
.pore complex
.intracellular membrane-bounded organelle
  + 7 more...
6 EBI-536879,EBI-742327 TRIP6  
  .focal adhesion assembly
.positive regulation of cell migration
.release of cytoplasmic sequestered NF-kappaB
  + 2 more...
.thyroid hormone receptor binding
.poly(A) RNA binding
.kinase binding
  + 2 more...
.focal adhesion
.plasma membrane
.cytoskeleton
  + 2 more...
7 EBI-536879,EBI-9870821 MIS18BP1  
  .cell division
.CENP-A containing nucleosome assembly
.mitotic nuclear division
.nucleosome assembly
.chromatin binding
.DNA binding
.nucleoplasm
.chromosome, centromeric region
8 EBI-536879,EBI-946029 C1orf94  
  .N/A .N/A .N/A
9 EBI-536879,EBI-746252 GCC1  
  .protein targeting to Golgi .N/A .plasma membrane
.Golgi apparatus
.cytoplasm
.Golgi membrane
10 EBI-536879,EBI-743488 CEP170P1  
  .N/A .identical protein binding .N/A
11 EBI-536879,EBI-301024 EIF4ENIF1  
  .N/A .poly(A) RNA binding
.protein transporter activity
.intracellular membrane-bounded organelle
.nuclear speck
.PML body
  + 4 more...
12 EBI-536879,EBI-1104552 MIS18A  
  .positive regulation of protein targeting to mitochondrion
.cell division
.regulation of DNA methylation
  + 4 more...
.N/A .cytoplasm
.nucleoplasm
.nucleus
.chromosome, centromeric region
13 EBI-536879,EBI-1105213 TFIP11  
  .biomineral tissue development
.RNA processing
.regulation of transcription, DNA-templated
  + 2 more...
.DNA binding .catalytic step 2 spliceosome
.U2-type post-mRNA release spliceosomal complex
.nuclear speck
  + 3 more...
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
bladder33
bone27
brain5
cervix20
embryonic tissue14
eye4
intestine4
kidney4
liver14
lymph22
lymph node44
mammary gland13
ovary19
pancreas9
placenta7
prostate5
skin4
stomach41
testis25
uterus12
Health State
TissuesTPM*
normal6
bladder carcinoma56
breast (mammary gland) tumor21
cervical tumor28
chondrosarcoma24
colorectal tumor8
gastrointestinal tumor25
germ cell tumor11
kidney tumor14
liver tumor20
lymphoma13
ovarian tumor26
pancreatic tumor19
prostate cancer9
retinoblastoma21
skin tumor7
soft tissue/muscle tissue tumor23
Developmental Stage
TissuesTPM*
adult6
embryoid body28
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adrenal gland1.4
appendix3.1
bone marrow5.9
colon4
duodenum3
esophagus1.5
lymph node4.8
ovary1.1
placenta2.4
skin2
small intestine3.2
spleen1
stomach1.5
testis19.2
urinary bladder1.1
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*606020, gene) Opa-interacting protein 5; OIP5OMIM


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