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> Protein (NX_O43709)
Protein (NX_O43709)
Protein
Gene SymbolWBSCR22 to neXtProt (NX_O43709)
DescriptionProbable 18S rRNA (guanine-N(7))-methyltransferase
Chromosome7
Location7q11.23 (73097355 ~ 73119491) to Ensembl
Sequene Features : Isoforms 3, Variants 28, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.chromatin modification
.rRNA processing
.regulation of transcription, DNA-templated
.transcription, DNA-templated
.poly(A) RNA binding
.methyltransferase activity
.cytoplasm
.nucleolus
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
3 28 3
2014-09-19protein level
3 22 3
2014-05-27protein level
3 22 3
2014-02-25protein level
2 22 3
2013-12-09protein level
2 19 3
2013-11-01protein level
2 18 3
2013-09-12protein level
2 18 3
2013-08-17protein level
2 18 3
2013-07-15protein level
2 11 3
2013-06-11protein level
2 11 3
2013-02-12protein level
2 6 3
2012-12-20protein level
2 6 3
2012-10-30protein level
2 7 3
2012-10-07protein level
2 7 3
2012-08-24protein level
2 6 3
2012-07-28protein level
2 6 3
2012-06-08protein level
2 6 3
2012-05-07protein level
2 5 3
2012-04-10protein level
2 5 3
2012-01-13protein level
2 3 3
2011-12-20protein level
2 3 3
2011-11-11protein level
2 3 3
2011-08-23protein level
2 3 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_O43709-1
0 9 0 31859.9897
NX_O43709-2
2 4 0 24343.7705
NX_O43709-3
0 9 0 33824.0148
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adrenal gland151
ascites75
bladder100
blood65
bone83
bone marrow143
brain47
cervix103
connective tissue26
embryonic tissue56
esophagus148
eye90
heart55
intestine107
kidney33
larynx42
liver63
lung95
lymph67
lymph node11
mammary gland52
mouth151
muscle141
nerve128
ovary88
pancreas173
pharynx147
placenta49
prostate63
salivary gland296
skin270
stomach135
testis119
thymus50
thyroid21
tonsil117
trachea38
umbilical cord145
uterus112
vascular58
Health State
TissuesTPM*
normal53
adrenal tumor79
bladder carcinoma227
breast (mammary gland) tumor85
cervical tumor57
chondrosarcoma72
colorectal tumor168
esophageal tumor173
gastrointestinal tumor151
germ cell tumor98
glioma55
head and neck tumor112
kidney tumor72
leukemia137
liver tumor93
lung tumor204
lymphoma83
non-neoplasia20
ovarian tumor52
pancreatic tumor161
primitive neuroectodermal tumor of the CNS118
prostate cancer86
retinoblastoma193
skin tumor398
soft tissue/muscle tissue tumor55
uterine tumor166
Developmental Stage
TissuesTPM*
adult70
embryoid body28
blastocyst65
neonate64
fetus26
infant42
juvenile179
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue40
adrenal gland46.7
appendix44.2
bone marrow50.7
cerebral cortex37.2
colon53.5
duodenum44
esophagus41.2
gallbladder41.6
heart muscle65.1
kidney45.5
liver28.5
lung43.2
lymph node53.9
ovary43
pancreas33.7
placenta35.7
prostate47.6
salivary gland43.5
skin43.2
small intestine39.7
spleen49
stomach49.7
testis138.1
thyroid gland62
urinary bladder47.9
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(#194050, phenotype) Williams-beuren syndrome; WBSOMIM


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