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> Protein (NX_O43739)
Protein (NX_O43739)
Protein
Gene SymbolCYTH3 to neXtProt (NX_O43739)
DescriptionCytohesin-3
Chromosome7
Location7p22.1 (6201407 ~ 6312275) to Ensembl
Sequene Features : Isoforms 2, Variants 31, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.establishment of epithelial cell polarity
.Golgi vesicle transport
.positive regulation of cell adhesion
  + 2 more...
.phosphatidylinositol-3,4,5-trisphosphate binding
.ARF guanyl-nucleotide exchange factor activity
.extrinsic component of cytoplasmic side of plasma membrane
.plasma membrane
.cytosol
.ruffle
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
2 31 0
2014-09-19protein level
2 24 0
2014-05-27protein level
2 24 0
2014-02-25protein level
2 23 0
2013-12-09protein level
2 22 0
2013-11-01protein level
2 21 0
2013-09-12protein level
2 21 0
2013-08-17protein level
2 21 0
2013-07-15protein level
2 13 0
2013-06-11protein level
2 13 0
2013-02-12protein level
2 5 0
2012-12-20protein level
2 5 0
2012-10-30protein level
2 6 0
2012-10-07protein level
2 6 0
2012-08-24protein level
2 3 0
2012-07-28protein level
2 3 0
2012-06-08protein level
2 0 0
2012-05-07protein level
2 0 0
2012-04-10protein level
2 0 0
2012-01-13protein level
2 0 0
2011-12-20protein level
2 1 0
2011-11-11protein level
2 1 0
2011-08-23transcript level
2 1 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_O43739-1
0 12 4 46319.295
NX_O43739-2
0 12 4 46262.2737
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-741648,EBI-6872807 SYCE1  
  .cell division
.synaptonemal complex assembly
.N/A .central element
2 EBI-741648,EBI-741671 CNKSR1  
  .Rho protein signal transduction
.Ras protein signal transduction
.transmembrane receptor protein tyrosine kinase signaling pathway
.protein binding, bridging .cell cortex
.cell-cell junction
.plasma membrane
3 EBI-741648,EBI-10185348 CCDC120  
  .N/A .N/A .N/A
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adipose tissue77
adrenal gland60
bladder33
blood8
bone83
brain46
connective tissue67
ear62
embryonic tissue9
eye43
heart33
intestine73
kidney28
liver19
lung20
lymph45
mammary gland19
mouth30
muscle9
ovary19
pancreas18
placenta187
prostate58
skin66
spleen18
stomach41
testis43
thymus25
tonsil58
trachea19
uterus77
vascular19
Health State
TissuesTPM*
normal50
breast (mammary gland) tumor21
chondrosarcoma144
colorectal tumor115
gastrointestinal tumor25
germ cell tumor26
glioma9
head and neck tumor7
kidney tumor14
liver tumor41
lymphoma27
non-neoplasia10
ovarian tumor39
pancreatic tumor38
primitive neuroectodermal tumor of the CNS31
prostate cancer77
skin tumor95
soft tissue/muscle tissue tumor23
uterine tumor66
Developmental Stage
TissuesTPM*
adult61
embryoid body14
blastocyst16
fetus57
infant42
juvenile35
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue25.6
adrenal gland9.2
appendix6.3
bone marrow6.6
cerebral cortex17.2
colon9.6
duodenum16.5
esophagus15
gallbladder13.8
heart muscle19.5
kidney10.8
liver2
lung18.9
lymph node5.8
ovary11.5
pancreas3.4
placenta38.2
prostate8.1
salivary gland7.5
skin15.8
small intestine17.7
spleen8.8
stomach9.5
testis22.4
thyroid gland23
urinary bladder9.9
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*605081, gene) Cytohesin 3; CYTH3OMIM


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