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> Protein (NX_O43747)
Protein (NX_O43747)
Protein
Gene SymbolAP1G1 to neXtProt (NX_O43747)
DescriptionAP-1 complex subunit gamma-1
Chromosome16
Location16q22.2 (71762913 ~ 71843104) to Ensembl
Sequene Features : Isoforms 2, Variants 82, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.Golgi to lysosome transport
.membrane organization
.regulation of defense response to virus by virus
  + 8 more...
.GTP-dependent protein binding
.kinesin binding
.Rab GTPase binding
  + 2 more...
.recycling endosome
.perinuclear region of cytoplasm
.intracellular membrane-bounded organelle
  + 13 more...
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
2 82 0
2014-09-19protein level
2 63 0
2014-05-27protein level
2 63 0
2014-02-25protein level
2 63 0
2013-12-09protein level
2 56 0
2013-11-01protein level
2 56 0
2013-09-12protein level
2 56 0
2013-08-17protein level
2 56 0
2013-07-15protein level
2 28 0
2013-06-11protein level
2 28 0
2013-02-12protein level
2 12 2
2012-12-20protein level
2 12 2
2012-10-30protein level
2 14 2
2012-10-07protein level
2 14 1
2012-08-24protein level
2 7 1
2012-07-28protein level
2 7 1
2012-06-08protein level
2 11 1
2012-05-07protein level
2 11 1
2012-04-10protein level
2 11 1
2012-01-13protein level
2 9 1
2011-12-20protein level
2 9 1
2011-11-11protein level
2 9 1
2011-08-23protein level
2 9 1
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_O43747-1
0 30 0 91292.8666
NX_O43747-2
0 30 0 91664.046
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-10185819,EBI-1054374 AP1S2  
  .membrane organization
.regulation of defense response to virus by virus
.antigen processing and presentation of exogenous peptide antigen via MHC class II
  + 3 more...
.protein transporter activity .trans-Golgi network membrane
.clathrin-coated endocytic vesicle membrane
.cytoplasmic vesicle membrane
  + 5 more...
2 EBI-447609,EBI-447043 RABEP1  
  .membrane fusion
.vesicle-mediated transport
.protein transport
  + 2 more...
.protein homodimerization activity
.GTPase activator activity
.recycling endosome
.intracellular membrane-bounded organelle
.endocytic vesicle
  + 2 more...
3 EBI-10185819,EBI-348604 UBL7  
  .N/A .N/A .N/A
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adipose tissue77
ascites75
bladder66
blood81
bone55
bone marrow41
brain139
connective tissue40
ear124
embryonic tissue61
eye81
heart33
intestine103
kidney52
liver43
lung59
lymph node178
mammary gland158
mouth90
muscle47
nerve64
ovary59
pancreas28
pharynx147
placenta95
prostate47
skin52
spleen18
stomach94
testis236
thymus62
thyroid42
trachea444
umbilical cord72
uterus107
vascular77
Health State
TissuesTPM*
normal96
bladder carcinoma113
breast (mammary gland) tumor171
chondrosarcoma48
colorectal tumor159
gastrointestinal tumor92
germ cell tumor151
glioma74
head and neck tumor97
kidney tumor29
leukemia95
liver tumor31
lung tumor9
non-neoplasia72
ovarian tumor78
pancreatic tumor19
prostate cancer67
skin tumor55
soft tissue/muscle tissue tumor63
uterine tumor66
Developmental Stage
TissuesTPM*
adult91
embryoid body57
blastocyst97
neonate32
fetus116
juvenile17
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue19.2
adrenal gland27.2
appendix26.8
bone marrow72.2
cerebral cortex28.8
colon27
duodenum22.3
esophagus27.4
gallbladder23.3
heart muscle12.5
kidney38.5
liver20.3
lung24.4
lymph node28.4
ovary19.1
pancreas15.2
placenta22.9
prostate21.5
salivary gland18.2
skin25
small intestine25.9
spleen24
stomach31.2
testis52.3
thyroid gland28.6
urinary bladder25.1
Tissues
TissuesExpression level
adrenal glandHigh
appendixHigh
bone marrowMedium
breastHigh
bronchusHigh
cerebellumHigh
cerebral cortexHigh
cervix, uterineMedium
colonHigh
duodenumHigh
endometrium 1High
endometrium 2High
epididymisHigh
esophagusMedium
fallopian tubeHigh
gallbladderHigh
heart muscleMedium
hippocampusHigh
kidneyHigh
lateral ventricleHigh
liverLow
lungHigh
lymph nodeHigh
nasopharynxHigh
oral mucosaMedium
ovaryHigh
pancreasHigh
parathyroid glandHigh
placentaHigh
prostateHigh
rectumHigh
salivary glandHigh
seminal vesicleHigh
skeletal muscleLow
skin 1Medium
skin 2High
small intestineHigh
smooth muscleLow
soft tissue 1Medium
soft tissue 2Medium
spleenMedium
stomach 1Medium
stomach 2High
testisHigh
thyroid glandHigh
tonsilHigh
urinary bladderHigh
vaginaMedium
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Expression level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*603533, gene) Adaptor-related protein complex 1, gamma-1 subunit; AP1G1OMIM


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