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> Protein (NX_O43776)
Protein (NX_O43776)
Protein
Gene SymbolNARS to neXtProt (NX_O43776)
DescriptionAsparagine--tRNA ligase, cytoplasmic
Chromosome18
Location18q21.31 (55267888 ~ 55289445) to Ensembl
Sequene Features : Isoforms 2, Variants 61, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.gene expression
.asparaginyl-tRNA aminoacylation
.tRNA aminoacylation for protein translation
.ATP binding
.asparagine-tRNA ligase activity
.nucleic acid binding
.extracellular exosome
.cytosol
.mitochondrion
.cytoplasm
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
2 61 8
2014-09-19protein level
1 50 8
2014-05-27protein level
1 50 8
2014-02-25protein level
1 48 7
2013-12-09protein level
1 35 7
2013-11-01protein level
1 33 4
2013-09-12protein level
1 33 5
2013-08-17protein level
1 33 5
2013-07-15protein level
1 24 3
2013-06-11protein level
1 24 3
2013-02-12protein level
1 7 3
2012-12-20protein level
1 7 3
2012-10-30protein level
1 9 3
2012-10-07protein level
1 9 3
2012-08-24protein level
1 7 3
2012-07-28protein level
1 7 3
2012-06-08protein level
1 8 3
2012-05-07protein level
1 8 3
2012-04-10protein level
1 8 3
2012-01-13protein level
1 3 3
2011-12-20protein level
1 3 3
2011-11-11protein level
1 3 3
2011-08-23protein level
1 3 3
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_O43776-1
16 5 0 62902.3395
NX_O43776-2
1 5 0 20020.3131
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adrenal gland151
ascites577
bladder368
blood237
bone111
bone marrow410
brain427
cervix144
connective tissue248
embryonic tissue211
esophagus248
eye129
heart145
intestine228
kidney346
larynx85
liver219
lung140
lymph270
lymph node111
mammary gland165
mouth453
muscle272
nerve193
ovary59
pancreas65
parathyroid145
pharynx49
pituitary gland181
placenta204
prostate216
salivary gland148
skin256
spleen711
stomach188
testis193
thymus577
thyroid214
trachea231
umbilical cord72
uterus245
vascular425
Health State
TissuesTPM*
normal266
bladder carcinoma113
breast (mammary gland) tumor182
cervical tumor202
chondrosarcoma72
colorectal tumor168
esophageal tumor289
gastrointestinal tumor295
germ cell tumor421
glioma139
head and neck tumor283
kidney tumor232
leukemia264
liver tumor239
lung tumor145
lymphoma249
non-neoplasia248
ovarian tumor65
pancreatic tumor76
primitive neuroectodermal tumor of the CNS370
prostate cancer154
retinoblastoma323
skin tumor191
soft tissue/muscle tissue tumor143
uterine tumor210
Developmental Stage
TissuesTPM*
adult176
embryoid body200
blastocyst244
neonate901
fetus258
infant510
juvenile719
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue58.4
adrenal gland69.1
appendix78.3
bone marrow62.9
cerebral cortex80.5
colon98.6
duodenum87.7
esophagus66.9
gallbladder63.6
heart muscle76
kidney103.2
liver39.2
lung51.5
lymph node64.4
ovary48
pancreas33.4
placenta51.1
prostate65.6
salivary gland52.1
skin50.7
small intestine77.2
spleen53
stomach75.6
testis43.2
thyroid gland96.8
urinary bladder77.1
Tissues
TissuesExpression level
adrenal glandMedium
appendixHigh
bone marrowMedium
breastMedium
bronchusMedium
cerebellumHigh
cerebral cortexMedium
cervix, uterineMedium
colonHigh
duodenumMedium
endometrium 1Medium
endometrium 2Low
epididymisMedium
esophagusMedium
fallopian tubeMedium
gallbladderHigh
heart muscleLow
hippocampusMedium
kidneyMedium
lateral ventricleMedium
liverMedium
lungMedium
lymph nodeMedium
nasopharynxMedium
oral mucosaMedium
ovaryMedium
pancreasHigh
parathyroid glandMedium
placentaHigh
prostateMedium
rectumHigh
salivary glandMedium
seminal vesicleMedium
skeletal muscleLow
skin 1Medium
skin 2Medium
small intestineMedium
smooth muscleLow
soft tissue 1Low
soft tissue 2Low
spleenMedium
stomach 1High
stomach 2High
testisMedium
thyroid glandMedium
tonsilMedium
urinary bladderMedium
vaginaMedium
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Expression level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*108410, gene) Asparaginyl-trna synthetase; NARSOMIM


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