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> Protein (NX_O43805)
Protein (NX_O43805)
Protein
Gene SymbolSSNA1 to neXtProt (NX_O43805)
DescriptionSjoegren syndrome nuclear autoantigen 1
Chromosome9
Location9q34.3 (140083099 ~ 140084822) to Ensembl
Sequene Features : Isoforms 1, Variants 8, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.ciliary receptor clustering involved in smoothened signaling pathway
.intraciliary transport
.organelle organization
  + 2 more...
.N/A .ciliary basal body
.cytosol
.centrosome
.nucleus
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 8 2
2014-09-19protein level
1 7 2
2014-05-27protein level
1 7 2
2014-02-25protein level
1 7 2
2013-12-09protein level
1 5 2
2013-11-01protein level
1 4 2
2013-09-12protein level
1 4 2
2013-08-17protein level
1 4 2
2013-07-15protein level
1 3 0
2013-06-11protein level
1 3 0
2013-02-12protein level
1 1 0
2012-12-20protein level
1 1 0
2012-10-30protein level
1 1 0
2012-10-07protein level
1 1 0
2012-08-24protein level
1 1 0
2012-07-28protein level
1 1 0
2012-06-08protein level
1 3 0
2012-05-07protein level
1 5 0
2012-04-10protein level
1 5 0
2012-01-13protein level
1 3 0
2011-12-20protein level
1 3 0
2011-11-11protein level
1 3 0
2011-08-23protein level
1 3 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_O43805-1
5 0 0 13587.8949
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-2515299,EBI-727004 SDCBP  
  .positive regulation of extracellular exosome assembly
.positive regulation of exosomal secretion
.ephrin receptor signaling pathway
  + 9 more...
.protein N-terminus binding
.protein heterodimerization activity
.syndecan binding
  + 4 more...
.blood microparticle
.extracellular exosome
.melanosome
  + 12 more...
2 EBI-2515299,EBI-2339219 EHHADH  
  .fatty acid beta-oxidation
.internal protein amino acid acetylation
.coenzyme binding
.enzyme binding
.receptor binding
  + 3 more...
.cytosol
.peroxisome
.mitochondrion
3 EBI-2515299,EBI-954696 TCEANC  
  .regulation of DNA-templated transcription, elongation
.regulation of transcription from RNA polymerase II promoter
.transcription, DNA-templated
.DNA binding .nucleus
4 EBI-2515299,EBI-739832 LNX1  
  .protein homooligomerization
.protein ubiquitination involved in ubiquitin-dependent protein catabolic process
.ligase activity
.zinc ion binding
.ubiquitin-protein transferase activity
.cytoplasm
5 EBI-2515299,EBI-2932492 TXN2  
  .oxidation-reduction process
.response to axon injury
.cell redox homeostasis
  + 12 more...
.peptide-methionine (R)-S-oxide reductase activity
.oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor
.protein disulfide oxidoreductase activity
.peptide-methionine (S)-S-oxide reductase activity
.neuronal cell body
.dendrite
.mitochondrial matrix
  + 2 more...
6 EBI-2515299,EBI-349832 GOPC  
  .protein homooligomerization
.regulation of catalytic activity
.apical protein localization
  + 6 more...
.ion channel binding .postsynaptic membrane
.protein complex
.Golgi-associated vesicle membrane
  + 9 more...
7 EBI-2515299,EBI-3258000 TBC1D7  
  .negative regulation of cilium assembly
.activation of GTPase activity
.response to growth factor
  + 2 more...
.Rab GTPase binding
.GTPase activator activity
.ciliary basal body
.cytoplasmic vesicle
.cytoplasmic membrane-bounded vesicle
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adrenal gland60
ascites25
blood32
bone83
brain21
cervix144
connective tissue20
embryonic tissue23
eye71
heart22
intestine30
kidney14
liver4
lung50
lymph112
lymph node44
mammary gland46
muscle47
nerve64
ovary19
pancreas23
placenta67
prostate73
salivary gland49
skin94
stomach20
testis29
thyroid42
tonsil117
uterus30
vascular19
Health State
TissuesTPM*
normal35
adrenal tumor158
breast (mammary gland) tumor64
cervical tumor144
chondrosarcoma48
colorectal tumor17
gastrointestinal tumor50
germ cell tumor41
glioma65
head and neck tumor14
kidney tumor43
leukemia21
liver tumor10
lung tumor68
lymphoma124
non-neoplasia20
ovarian tumor13
pancreatic tumor9
primitive neuroectodermal tumor of the CNS39
prostate cancer67
retinoblastoma21
skin tumor135
soft tissue/muscle tissue tumor55
uterine tumor44
Developmental Stage
TissuesTPM*
adult43
embryoid body28
blastocyst16
fetus55
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue33.2
adrenal gland27
appendix35
bone marrow36.5
cerebral cortex25.2
colon32.6
duodenum35.1
esophagus42.1
gallbladder24.6
heart muscle41.5
kidney39.2
liver14.8
lung35.7
lymph node44.9
ovary22.3
pancreas30.1
placenta29.2
prostate33.3
salivary gland42.1
skin35.7
small intestine32.6
spleen37.1
stomach37.3
testis72.3
thyroid gland26.1
urinary bladder36
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Disease
No.Disease DescriptionRef.
1(*610882, gene) Sjogren syndrome nuclear autoantigen 1; SSNA1OMIM


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