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> Protein (NX_O43815)
Protein (NX_O43815)
Protein
Gene SymbolSTRN to neXtProt (NX_O43815)
DescriptionStriatin
Chromosome2
Location2p22.2 (37070783 ~ 37193615) to Ensembl
Sequene Features : Isoforms 2, Variants 95, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.tight junction assembly
.dendrite development
.Wnt signaling pathway
  + 2 more...
.armadillo repeat domain binding
.protein phosphatase 2A binding
.protein complex binding
  + 2 more...
.postsynaptic membrane
.dendritic spine
.neuronal cell body
  + 4 more...
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
2 95 3
2014-09-19protein level
2 67 3
2014-05-27protein level
2 67 4
2014-02-25protein level
2 66 4
2013-12-09protein level
2 53 4
2013-11-01protein level
2 51 2
2013-09-12protein level
2 51 3
2013-08-17protein level
2 51 3
2013-07-15protein level
2 37 3
2013-06-11protein level
2 37 3
2013-02-12protein level
2 13 6
2012-12-20protein level
2 13 6
2012-10-30protein level
2 16 6
2012-10-07protein level
2 16 3
2012-08-24protein level
2 13 3
2012-07-28protein level
2 13 3
2012-06-08protein level
2 17 3
2012-05-07protein level
2 16 3
2012-04-10protein level
2 16 3
2012-01-13protein level
2 8 3
2011-12-20protein level
2 8 3
2011-11-11protein level
2 8 3
2011-08-23protein level
2 8 3
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_O43815-1
3 32 0 86078.5388
NX_O43815-2
2 32 0 80710.7725
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-1046642,EBI-618295 STK25  
  .Golgi reassembly
.establishment of Golgi localization
.Golgi localization
  + 12 more...
.metal ion binding
.protein homodimerization activity
.ATP binding
  + 2 more...
.extracellular exosome
.Golgi apparatus
.cytoplasm
2 EBI-1046642,EBI-302388 PPP2R1A  
  .positive regulation of extrinsic apoptotic signaling pathway in absence of ligand
.peptidyl-serine dephosphorylation
.regulation of cell differentiation
  + 24 more...
.protein heterodimerization activity
.protein phosphatase type 2A regulator activity
.protein serine/threonine phosphatase activity
.antigen binding
.extracellular exosome
.membrane
.microtubule cytoskeleton
  + 5 more...
3 EBI-1046642,EBI-712311 PPP2CA  
  .positive regulation of protein serine/threonine kinase activity
.protein heterotrimerization
.meiotic cell cycle
  + 25 more...
.metal ion binding
.protein serine/threonine phosphatase activity
.extracellular exosome
.membrane
.microtubule cytoskeleton
  + 7 more...
4 EBI-1046642,EBI-1053857 STRN3  
  .positive regulation of transcription from RNA polymerase II promoter
.negative regulation of transcription, DNA-templated
.negative regulation of intracellular estrogen receptor signaling pathway
  + 2 more...
.armadillo repeat domain binding
.protein phosphatase 2A binding
.protein complex binding
  + 2 more...
.protein complex
.neuronal cell body
.dendrite
  + 5 more...
5 EBI-1046642,EBI-726876 RINT1  
  .regulation of signal transduction involved in mitotic G2 DNA damage checkpoint
.regulation of ER to Golgi vesicle-mediated transport
.Golgi vesicle transport
  + 2 more...
.N/A .endoplasmic reticulum membrane
.endoplasmic reticulum
6 EBI-1046642,EBI-740195 PDCD10  
  .negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis
.Golgi reassembly
.negative regulation of cell migration involved in sprouting angiogenesis
  + 16 more...
.protein N-terminus binding
.protein homodimerization activity
.protein kinase binding
.extracellular exosome
.plasma membrane
.cytosol
  + 3 more...
7 EBI-1046642,EBI-4398527 TNKS2  
  .positive regulation of canonical Wnt signaling pathway
.protein auto-ADP-ribosylation
.protein localization to chromosome, telomeric region
  + 6 more...
.metal ion binding
.enzyme binding
.NAD+ ADP-ribosyltransferase activity
.perinuclear region of cytoplasm
.cytosol
.cytoplasm
  + 5 more...
8 EBI-1046642,EBI-1774273 CTTNBP2NL  
  .negative regulation of transmembrane transport
.negative regulation of transporter activity
.protein dephosphorylation
.protein phosphatase 2A binding .actin cytoskeleton
.cytoplasm
9 EBI-1046642,EBI-1105213 TFIP11  
  .biomineral tissue development
.RNA processing
.regulation of transcription, DNA-templated
  + 2 more...
.DNA binding .catalytic step 2 spliceosome
.U2-type post-mRNA release spliceosomal complex
.nuclear speck
  + 3 more...
10 EBI-1046642,EBI-765817 TRAF3IP3  
  .N/A .N/A .integral component of membrane
11 EBI-1046642,EBI-713935 MOB4  
  .transport .metal ion binding .perinuclear region of cytoplasm
.dendritic spine
.neuronal cell body
  + 4 more...
12 EBI-1046642,EBI-740175 STK24  
  .execution phase of apoptosis
.regulation of axon regeneration
.protein autophosphorylation
  + 13 more...
.metal ion binding
.ATP binding
.protein serine/threonine kinase activity
.protein kinase activity
.extracellular exosome
.membrane
.cytosol
  + 4 more...
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adrenal gland60
ascites25
bladder66
blood57
bone27
bone marrow20
brain37
connective tissue33
ear62
embryonic tissue23
esophagus49
eye47
heart111
intestine56
kidney23
larynx42
liver4
lung20
lymph node77
mammary gland39
muscle28
nerve64
ovary49
pancreas37
parathyroid145
placenta31
prostate5
skin23
stomach41
testis18
thymus25
uterus34
vascular19
Health State
TissuesTPM*
normal39
breast (mammary gland) tumor32
chondrosarcoma72
colorectal tumor62
esophageal tumor57
gastrointestinal tumor42
germ cell tumor22
kidney tumor29
leukemia84
liver tumor10
lung tumor9
non-neoplasia51
ovarian tumor39
pancreatic tumor19
retinoblastoma86
skin tumor31
soft tissue/muscle tissue tumor23
uterine tumor55
Developmental Stage
TissuesTPM*
adult37
embryoid body28
blastocyst32
fetus32
juvenile17
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue7.5
adrenal gland5.9
appendix9.7
bone marrow10
cerebral cortex13.2
colon11.2
duodenum7.5
esophagus21.7
gallbladder7.8
heart muscle17.1
kidney7.8
liver5.5
lung7.4
lymph node9
ovary7.7
pancreas2.8
placenta9.7
prostate6.4
salivary gland7.1
skin10.1
small intestine8.2
spleen7.5
stomach9.2
testis9.4
thyroid gland7.3
urinary bladder9.6
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*614765, gene) Striatin, calmodulin-binding protein; STRNOMIM


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