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> Protein (NX_O43820)
Protein (NX_O43820)
Protein
Gene SymbolHYAL3 to neXtProt (NX_O43820)
DescriptionHyaluronidase-3
Chromosome3
Location3p21.31 (50330262 ~ 50336899) to Ensembl
Sequene Features : Isoforms 4, Variants 51, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.cellular response to UV-B
.cellular response to tumor necrosis factor
.cellular response to interleukin-1
  + 6 more...
.hyaluronoglucuronidase activity
.hyalurononglucosaminidase activity
.cytoplasmic vesicle
.lysosome
.extracellular region
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
4 51 7
2014-09-19protein level
4 42 7
2014-05-27transcript level
4 42 7
2014-02-25transcript level
4 41 7
2013-12-09transcript level
4 31 7
2013-11-01transcript level
4 31 7
2013-09-12transcript level
4 31 7
2013-08-17transcript level
4 31 7
2013-07-15transcript level
4 25 7
2013-06-11transcript level
4 25 7
2013-02-12transcript level
4 14 19
2012-12-20transcript level
4 14 19
2012-10-30transcript level
4 17 19
2012-10-07transcript level
4 17 7
2012-08-24transcript level
4 13 7
2012-07-28transcript level
4 13 7
2012-06-08transcript level
4 14 7
2012-05-07transcript level
4 14 7
2012-04-10transcript level
4 14 7
2012-01-13transcript level
4 4 7
2011-12-20transcript level
4 4 7
2011-11-11transcript level
4 4 7
2011-08-23transcript level
4 4 7
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_O43820-1
0 18 0 46470.9875
NX_O43820-2
0 18 0 43573.5298
NX_O43820-3
0 6 0 18752.1782
NX_O43820-4
0 6 0 15854.7205
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-3913399,EBI-7875264 DAB1  
  .lateral motor column neuron migration
.Golgi localization
.negative regulation of axonogenesis
  + 15 more...
.N/A .perinuclear region of cytoplasm
.apical part of cell
.neuronal cell body
  + 5 more...
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adipose tissue77
blood8
bone27
bone marrow20
brain34
cervix41
connective tissue13
embryonic tissue4
eye23
intestine4
kidney9
liver4
lung8
lymph22
mammary gland13
muscle9
ovary19
pancreas23
placenta14
prostate5
skin37
stomach83
testis29
thymus12
thyroid42
uterus30
Health State
TissuesTPM*
normal21
breast (mammary gland) tumor10
cervical tumor28
chondrosarcoma36
gastrointestinal tumor59
germ cell tumor3
kidney tumor14
leukemia10
lung tumor19
lymphoma13
ovarian tumor26
pancreatic tumor47
primitive neuroectodermal tumor of the CNS47
prostate cancer9
retinoblastoma21
skin tumor63
soft tissue/muscle tissue tumor23
uterine tumor44
Developmental Stage
TissuesTPM*
adult21
embryoid body14
fetus1
infant42
juvenile17
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue1.2
adrenal gland1.1
appendix1.3
bone marrow20.9
cerebral cortex2.9
colon1.4
duodenum1.3
esophagus2
gallbladder1.6
heart muscle1.1
kidney1
liver2.3
lung1.1
lymph node1.1
placenta1.2
prostate2.1
salivary gland2.8
small intestine1.2
spleen1.1
stomach2.7
testis9.1
thyroid gland1
urinary bladder2.6
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*604038, gene) Hyaluronoglucosaminidase 3; HYAL3OMIM


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