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> Protein (NX_O43852)
Protein (NX_O43852)
Protein
Gene SymbolCALU to neXtProt (NX_O43852)
DescriptionCalumenin
Chromosome7
Location7q32.1 (128379346 ~ 128411861) to Ensembl
Sequene Features : Isoforms 15, Variants 33, PTMs 14 to neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.platelet activation
.blood coagulation
.platelet degranulation
.calcium ion binding .melanosome
.sarcoplasmic reticulum lumen
.membrane
  + 3 more...
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
15 33 14
2014-09-19protein level
15 26 14
2014-05-27protein level
15 26 14
2014-02-25protein level
15 26 13
2013-12-09protein level
15 20 12
2013-11-01protein level
15 19 6
2013-09-12protein level
15 19 6
2013-08-17protein level
15 19 6
2013-07-15protein level
15 12 4
2013-06-11protein level
15 12 4
2013-02-12protein level
4 5 14
2012-12-20protein level
4 7 14
2012-10-30protein level
4 7 14
2012-10-07protein level
4 7 4
2012-08-24protein level
4 7 4
2012-07-28protein level
4 7 4
2012-06-08protein level
4 9 4
2012-05-07protein level
4 7 4
2012-04-10protein level
2 7 4
2012-01-13protein level
2 5 4
2011-12-20protein level
2 5 4
2011-11-11protein level
2 5 4
2011-08-23protein level
2 5 4
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_O43852-1
0 15 0 37083.442
NX_O43852-10
1 11 0 26309.4395
NX_O43852-11
0 8 0 19980.5883
NX_O43852-12
0 4 0 8506.0596
NX_O43852-13
0 8 0 16280.9071
NX_O43852-14
0 9 0 17224.4093
NX_O43852-15
0 7 0 19443.0015
NX_O43852-2
0 14 0 37111.2662
NX_O43852-3
0 16 0 38026.9442
NX_O43852-4
0 15 0 38054.7684
NX_O43852-5
0 11 0 26874.8289
NX_O43852-6
1 12 0 30937.5296
NX_O43852-7
1 7 0 18776.7807
NX_O43852-8
0 9 0 23504.082
NX_O43852-9
0 8 0 17628.5035
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-1171069,EBI-10173939 UBQLN1  
  .regulation of autophagic vacuole assembly
.positive regulation of ER-associated ubiquitin-dependent protein catabolic process
.regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
  + 8 more...
.identical protein binding
.polyubiquitin binding
.kinase binding
.perinuclear region of cytoplasm
.protein complex
.aggresome
  + 6 more...
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adipose tissue233
adrenal gland455
ascites652
bladder133
blood16
bone195
bone marrow82
brain20
cervix82
connective tissue33
ear186
embryonic tissue37
esophagus49
eye23
heart178
intestine86
kidney61
liver48
lung83
lymph22
lymph node55
mammary gland119
mouth166
muscle28
ovary98
pancreas32
pharynx24
pituitary gland60
placenta194
prostate73
salivary gland49
skin170
stomach104
testis107
umbilical cord290
uterus120
vascular116
Health State
TissuesTPM*
normal72
adrenal tumor790
bladder carcinoma56
breast (mammary gland) tumor150
cervical tumor202
chondrosarcoma374
colorectal tumor97
esophageal tumor57
gastrointestinal tumor101
germ cell tumor159
glioma55
head and neck tumor29
kidney tumor58
leukemia21
liver tumor72
lung tumor107
lymphoma83
non-neoplasia41
ovarian tumor65
pancreatic tumor28
primitive neuroectodermal tumor of the CNS23
prostate cancer57
retinoblastoma43
skin tumor55
soft tissue/muscle tissue tumor7
uterine tumor110
Developmental Stage
TissuesTPM*
adult276
embryoid body457
blastocyst195
neonate1866
fetus256
infant382
juvenile863
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue75.1
adrenal gland47.2
appendix106.8
bone marrow13.2
cerebral cortex27.6
colon62.1
duodenum28.4
esophagus54.5
gallbladder85.5
heart muscle160.3
kidney30.1
liver34
lung46.5
lymph node32.2
ovary41.9
pancreas21.3
placenta155.2
prostate83.5
salivary gland41.4
skin19.1
small intestine28.5
spleen31.6
stomach44.7
testis35.2
thyroid gland71.1
urinary bladder126.5
Tissues
TissuesExpression level
adrenal glandHigh
appendixLow
bone marrowMedium
breastHigh
bronchusLow
cerebellumMedium
cerebral cortexHigh
cervix, uterineMedium
colonMedium
duodenumLow
endometrium 1High
endometrium 2High
epididymisMedium
esophagusMedium
fallopian tubeMedium
gallbladderMedium
heart muscleMedium
hippocampusHigh
kidneyMedium
lateral ventricleHigh
liverHigh
lungHigh
lymph nodeMedium
nasopharynxLow
oral mucosaMedium
ovaryLow
pancreasMedium
parathyroid glandMedium
placentaHigh
prostateMedium
rectumMedium
salivary glandMedium
seminal vesicleHigh
skeletal muscleMedium
skin 1Medium
skin 2Medium
small intestineMedium
smooth muscleMedium
soft tissue 1High
soft tissue 2High
spleenHigh
stomach 1High
stomach 2Medium
testisMedium
thyroid glandHigh
tonsilMedium
urinary bladderMedium
vaginaLow
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Expression level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*603420, gene) Calumenin; CALUOMIM


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