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> Protein (NX_O60218)
Protein (NX_O60218)
Protein
Gene SymbolAKR1B10 to neXtProt (NX_O60218)
DescriptionAldo-keto reductase family 1 member B10
Chromosome7
Location7q33 (134212344 ~ 134226160) to Ensembl
Sequene Features : Isoforms 1, Variants 65, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.doxorubicin metabolic process
.daunorubicin metabolic process
.farnesol catabolic process
  + 5 more...
.indanol dehydrogenase activity
.geranylgeranyl reductase activity
.aldo-keto reductase (NADP) activity
.retinal dehydrogenase activity
.extracellular exosome
.cytosol
.lysosome
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 65 2
2014-09-19protein level
1 49 2
2014-05-27protein level
1 49 2
2014-02-25protein level
1 49 2
2013-12-09protein level
1 37 2
2013-11-01protein level
1 37 2
2013-09-12protein level
1 37 2
2013-08-17protein level
1 37 2
2013-07-15protein level
1 27 2
2013-06-11protein level
1 27 2
2013-02-12protein level
1 13 6
2012-12-20protein level
1 13 6
2012-10-30protein level
1 14 6
2012-10-07protein level
1 14 6
2012-08-24protein level
1 14 6
2012-07-28protein level
1 14 6
2012-06-08protein level
1 19 6
2012-05-07protein level
1 17 6
2012-04-10protein level
1 17 6
2012-01-13protein level
1 10 6
2011-12-20protein level
1 10 6
2011-11-11protein level
1 10 6
2011-08-23protein level
1 10 6
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_O60218-1
10 0 8 35996.7344
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-1572139,EBI-717681 ACACA  
  .malonyl-CoA biosynthetic process
.lipid homeostasis
.protein homotetramerization
  + 14 more...
.metal ion binding
.ATP binding
.biotin carboxylase activity
.acetyl-CoA carboxylase activity
.extracellular exosome
.actin cytoskeleton
.cytosol
  + 3 more...
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
ascites125
brain2
connective tissue13
embryonic tissue4
esophagus99
eye4
intestine43
kidney33
liver73
lung203
mouth45
muscle18
pancreas18
pharynx24
placenta7
skin4
stomach73
uterus25
Health State
TissuesTPM*
normal6
esophageal tumor57
gastrointestinal tumor75
glioma27
head and neck tumor29
kidney tumor58
liver tumor135
lung tumor593
pancreatic tumor28
skin tumor7
soft tissue/muscle tissue tumor15
uterine tumor22
Developmental Stage
TissuesTPM*
adult19
blastocyst16
fetus1
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adrenal gland1.4
appendix10
colon81.7
duodenum562.4
esophagus89.6
gallbladder227.2
kidney6.1
liver18.7
prostate1
skin2.2
small intestine328.9
stomach414.9
testis1.3
urinary bladder8.1
Tissues
TissuesExpression level
duodenumMedium
gallbladderMedium
small intestineMedium
stomach 1Medium
stomach 2Medium
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Expression level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*604707, gene) Aldo-keto reductase family 1, member b10; AKR1B10OMIM


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