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> Protein (NX_O60232)
Protein (NX_O60232)
Protein
Gene SymbolSSSCA1 to neXtProt (NX_O60232)
DescriptionSjoegren syndrome/scleroderma autoantigen 1
Chromosome11
Location11q13.1 (65337901 ~ 65341413) to Ensembl
Sequene Features : Isoforms 1, Variants 21, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.cell division
.mitotic nuclear division
.N/A .N/A
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 21 6
2014-09-19protein level
1 19 6
2014-05-27protein level
1 19 6
2014-02-25protein level
1 19 6
2013-12-09protein level
1 16 6
2013-11-01protein level
1 15 6
2013-09-12protein level
1 15 6
2013-08-17protein level
1 15 6
2013-07-15protein level
1 12 3
2013-06-11protein level
1 12 3
2013-02-12protein level
1 9 3
2012-12-20protein level
1 8 3
2012-10-30protein level
1 11 3
2012-10-07protein level
1 11 3
2012-08-24protein level
1 11 3
2012-07-28protein level
1 11 3
2012-06-08protein level
1 11 3
2012-05-07protein level
1 9 3
2012-04-10protein level
1 9 3
2012-01-13protein level
1 3 3
2011-12-20protein level
1 3 3
2011-11-11protein level
1 3 3
2011-08-23protein level
1 3 2
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_O60232-1
8 0 0 21460.6248
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-741415,EBI-749483 SNAPC5  
  .gene expression
.transcription initiation from RNA polymerase III promoter
.transcription from RNA polymerase III promoter
.transcription from RNA polymerase II promoter
.sequence-specific DNA binding transcription factor activity .nucleolus
.nucleoplasm
.nucleus
2 EBI-741415,EBI-741406 CCNH  
  .positive regulation of viral transcription
.positive regulation of transcription from RNA polymerase II promoter
.negative regulation of gene expression, epigenetic
  + 20 more...
.cyclin-dependent protein serine/threonine kinase regulator activity
.kinase activity
.TFIIK complex
.cyclin-dependent protein kinase activating kinase holoenzyme complex
.holo TFIIH complex
  + 2 more...
3 EBI-741415,EBI-357407 CCT2  
  .toxin transport
.chaperone-mediated protein complex assembly
.'de novo' posttranslational protein folding
  + 3 more...
.unfolded protein binding
.ubiquitin protein ligase binding
.ATP binding
.extracellular exosome
.cell body
.microtubule
  + 4 more...
4 EBI-741415,EBI-357046 CCT7  
  .toxin transport
.'de novo' posttranslational protein folding
.cellular protein metabolic process
  + 2 more...
.unfolded protein binding
.ATP binding
.extracellular exosome
.cell body
.microtubule
  + 5 more...
5 EBI-741415,EBI-765817 TRAF3IP3  
  .N/A .N/A .integral component of membrane
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adrenal gland30
ascites100
bladder33
blood32
bone13
bone marrow61
brain10
cervix61
embryonic tissue23
esophagus99
eye23
heart22
intestine60
kidney23
liver73
lung14
lymph22
lymph node33
mammary gland39
ovary68
pancreas112
parathyroid339
pharynx24
placenta14
prostate42
salivary gland49
skin52
stomach41
testis18
uterus30
vascular58
Health State
TissuesTPM*
normal32
breast (mammary gland) tumor21
chondrosarcoma12
colorectal tumor88
esophageal tumor115
gastrointestinal tumor50
germ cell tumor11
glioma9
head and neck tumor7
kidney tumor29
leukemia42
liver tumor20
lung tumor29
lymphoma13
non-neoplasia31
ovarian tumor91
pancreatic tumor47
primitive neuroectodermal tumor of the CNS39
prostate cancer48
retinoblastoma43
skin tumor47
soft tissue/muscle tissue tumor31
Developmental Stage
TissuesTPM*
adult39
embryoid body14
blastocyst16
fetus23
infant42
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue17.8
adrenal gland20.9
appendix23.8
bone marrow32.4
cerebral cortex22
colon13.5
duodenum17.5
esophagus17
gallbladder17.1
heart muscle27
kidney23.3
liver13.7
lung20.3
lymph node28
ovary20
pancreas30.9
placenta22.3
prostate26.3
salivary gland32
skin14
small intestine15.5
spleen24.6
stomach17.7
testis31.6
thyroid gland22.4
urinary bladder21.5
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*606044, gene) Sjogren syndrome/scleroderma autoantigen 1; SSSCA1OMIM


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