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> Protein (NX_O60248)
Protein (NX_O60248)
Protein
Gene SymbolSOX15 to neXtProt (NX_O60248)
DescriptionProtein SOX-15
Chromosome17
Location17p13.1 (7491496 ~ 7493488) to Ensembl
Sequene Features : Isoforms 2, Variants 18, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.positive regulation of myoblast proliferation
.positive regulation of G0 to G1 transition
.myoblast development
  + 10 more...
.sequence-specific DNA binding transcription factor activity
.chromatin binding
.DNA binding
.sequence-specific DNA binding RNA polymerase II transcription factor activity
.nuclear transcription factor complex
.cytoplasm
.nucleus
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
2 18 1
2014-09-19protein level
1 15 1
2014-05-27protein level
1 15 1
2014-02-25protein level
1 15 1
2013-12-09protein level
1 7 1
2013-11-01protein level
1 7 1
2013-09-12protein level
1 7 1
2013-08-17protein level
1 7 1
2013-07-15protein level
1 2 1
2013-06-11protein level
1 2 1
2013-02-12protein level
1 1 1
2012-12-20protein level
1 2 1
2012-10-30protein level
1 2 1
2012-10-07protein level
1 2 1
2012-08-24protein level
1 1 1
2012-07-28protein level
1 1 1
2012-06-08protein level
1 6 1
2012-05-07protein level
1 6 1
2012-04-10protein level
1 6 1
2012-01-13protein level
1 5 1
2011-12-20protein level
1 5 1
2011-11-11protein level
1 5 1
2011-08-23protein level
1 5 1
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_O60248-1
3 7 1 25235.5028
NX_O60248-2
1 7 1 19380.624
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-5452954,EBI-711810 BHLHE40  
  .negative regulation of transcription, DNA-templated
.negative regulation of sequence-specific DNA binding transcription factor activity
.entrainment of circadian clock by photoperiod
  + 4 more...
.E-box binding
.protein heterodimerization activity
.MRF binding
  + 10 more...
.Golgi apparatus
.nucleolus
.nucleoplasm
.nucleus
2 EBI-5452954,EBI-3957665 HSFY1  
  .transcription, DNA-templated .sequence-specific DNA binding
.sequence-specific DNA binding transcription factor activity
.cytoplasm
.nucleus
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
brain11
embryonic tissue18
esophagus99
eye19
kidney4
liver4
lung2
mouth15
ovary9
pancreas9
pituitary gland60
placenta14
skin23
testis6
Health State
TissuesTPM*
normal6
esophageal tumor115
germ cell tumor18
glioma74
non-neoplasia20
ovarian tumor13
pancreatic tumor19
skin tumor15
Developmental Stage
TissuesTPM*
adult4
blastocyst48
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
bone marrow1.5
cerebral cortex3.9
esophagus12.9
heart muscle2.4
ovary5.4
prostate4.2
salivary gland1.9
skin25.8
testis1.1
urinary bladder1.8
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*601297, gene) Sry-box 15; SOX15OMIM


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