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> Protein (NX_O60307)
Protein (NX_O60307)
Protein
Gene SymbolMAST3 to neXtProt (NX_O60307)
DescriptionMicrotubule-associated serine/threonine-protein kinase 3
Chromosome19
Location19p13.11 (18208603 ~ 18262502) to Ensembl
Sequene Features : Isoforms 1, Variants 111, PTMs 11 to neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.N/A .ATP binding
.protein serine/threonine kinase activity
.magnesium ion binding
.N/A
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 111 11
2014-09-19protein level
1 74 11
2014-05-27protein level
1 74 14
2014-02-25protein level
1 72 14
2013-12-09protein level
1 55 14
2013-11-01protein level
1 53 14
2013-09-12protein level
1 53 14
2013-08-17protein level
1 53 14
2013-07-15protein level
1 28 13
2013-06-11protein level
1 28 13
2013-02-12protein level
1 12 17
2012-12-20protein level
1 14 17
2012-10-30protein level
1 16 17
2012-10-07protein level
1 16 17
2012-08-24protein level
1 16 17
2012-07-28protein level
1 16 17
2012-06-08protein level
1 17 17
2012-05-07protein level
1 8 17
2012-04-10protein level
1 8 17
2012-01-13protein level
1 11 17
2011-12-20protein level
1 11 17
2011-11-11protein level
1 11 16
2011-08-23protein level
1 11 16
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_O60307-1
46 0 8 143048.3993
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-311420,EBI-696162 PTEN  
  .positive regulation of apoptotic signaling pathway
.negative regulation of synaptic vesicle clustering
.positive regulation of excitatory postsynaptic membrane potential
  + 91 more...
.phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity
.inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity
.PDZ domain binding
  + 10 more...
.postsynaptic membrane
.Schmidt-Lanterman incisure
.dendritic spine
  + 12 more...
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
ascites25
blood40
bone41
brain34
embryonic tissue4
eye19
intestine8
kidney14
liver24
lung20
lymph45
lymph node211
mammary gland6
mouth15
nerve64
ovary9
pancreas23
placenta3
prostate26
skin33
testis9
trachea19
uterus12
Health State
TissuesTPM*
normal23
breast (mammary gland) tumor10
chondrosarcoma36
colorectal tumor8
gastrointestinal tumor8
germ cell tumor3
glioma83
head and neck tumor7
leukemia42
liver tumor20
lung tumor19
lymphoma27
non-neoplasia20
ovarian tumor13
primitive neuroectodermal tumor of the CNS15
prostate cancer38
skin tumor39
soft tissue/muscle tissue tumor15
uterine tumor11
Developmental Stage
TissuesTPM*
adult24
embryoid body14
fetus12
infant42
juvenile17
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue4.2
adrenal gland3.3
appendix8.5
bone marrow8.4
cerebral cortex26.1
colon5.5
duodenum8.7
esophagus2.1
gallbladder3.4
heart muscle2.5
kidney5
liver2.6
lung5.2
lymph node10.1
ovary4.2
pancreas7.4
placenta2.5
prostate3
salivary gland3.4
skin5.9
small intestine8.5
spleen12.7
stomach4.5
testis2.8
thyroid gland2.7
urinary bladder3.7
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*612258, gene) Microtubule-associated serine/threonine kinase 3; MAST3OMIM


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