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> Protein (NX_O60381)
Protein (NX_O60381)
Protein
Gene SymbolHBP1 to neXtProt (NX_O60381)
DescriptionHMG box-containing protein 1
Chromosome7
Location7q22.3 (106809406 ~ 106842974) to Ensembl
Sequene Features : Isoforms 3, Variants 48, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.positive regulation of potassium ion transport
.Wnt signaling pathway
.cell cycle arrest
  + 2 more...
.RNA binding
.DNA binding
.nucleoplasm
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
3 48 3
2014-09-19protein level
3 36 3
2014-05-27protein level
3 36 3
2014-02-25protein level
3 35 3
2013-12-09protein level
3 29 3
2013-11-01protein level
3 28 2
2013-09-12protein level
3 28 2
2013-08-17protein level
3 28 2
2013-07-15protein level
3 17 1
2013-06-11protein level
3 17 1
2013-02-12protein level
3 8 0
2012-12-20protein level
3 8 0
2012-10-30protein level
3 7 0
2012-10-07protein level
3 7 0
2012-08-24protein level
3 5 0
2012-07-28protein level
3 5 0
2012-06-08protein level
3 7 0
2012-05-07protein level
3 5 0
2012-04-10protein level
3 5 0
2012-01-13protein level
3 5 0
2011-12-20protein level
3 5 0
2011-11-11protein level
3 5 0
2011-08-23protein level
3 5 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_O60381-1
1 22 0 57608.159
NX_O60381-2
0 21 0 51399.9553
NX_O60381-3
1 22 0 57662.2133
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-954175,EBI-491274 RB1  
  .negative regulation of G1/S transition of mitotic cell cycle
.hepatocyte apoptotic process
.regulation of centromere complex assembly
  + 39 more...
.phosphoprotein binding
.androgen receptor binding
.identical protein binding
  + 7 more...
.Rb-E2F complex
.PML body
.SWI/SNF complex
  + 4 more...
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adipose tissue310
adrenal gland91
ascites25
bladder33
blood147
bone111
bone marrow41
brain81
cervix61
connective tissue107
ear248
embryonic tissue79
esophagus99
eye52
heart122
intestine99
kidney113
liver77
lung89
lymph node111
mammary gland72
mouth211
muscle84
nerve64
ovary49
pancreas18
parathyroid194
pharynx49
placenta52
prostate105
skin118
spleen93
stomach73
testis98
thymus163
thyroid64
trachea270
umbilical cord72
uterus245
vascular212
Health State
TissuesTPM*
normal104
breast (mammary gland) tumor53
cervical tumor86
chondrosarcoma120
colorectal tumor44
esophageal tumor115
gastrointestinal tumor33
germ cell tumor110
glioma74
head and neck tumor104
kidney tumor87
leukemia42
liver tumor83
lymphoma110
non-neoplasia93
ovarian tumor78
pancreatic tumor19
primitive neuroectodermal tumor of the CNS55
prostate cancer86
retinoblastoma21
skin tumor63
soft tissue/muscle tissue tumor103
uterine tumor122
Developmental Stage
TissuesTPM*
adult76
embryoid body42
blastocyst81
neonate289
fetus113
infant85
juvenile53
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue47.1
adrenal gland58
appendix31.3
bone marrow58.2
cerebral cortex18.3
colon35.7
duodenum33.1
esophagus57.7
gallbladder46.9
heart muscle47.6
kidney42.7
liver35.7
lung39.8
lymph node36.6
ovary56.3
pancreas17
placenta54.3
prostate40.4
salivary gland34.1
skin39
small intestine33.2
spleen40.9
stomach32.7
testis59.3
thyroid gland64
urinary bladder53.3
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected


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