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> Protein (NX_O60494)
Protein (NX_O60494)
Protein
Gene SymbolCUBN to neXtProt (NX_O60494)
DescriptionCubilin
Chromosome10
Location10p13 (16865963 ~ 17171830) to Ensembl
Sequene Features : Isoforms 1, Variants 661, PTMs 114 to neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.small molecule metabolic process
.lipoprotein transport
.vitamin D metabolic process
  + 9 more...
.protein homodimerization activity
.cobalamin binding
.calcium ion binding
  + 2 more...
.extracellular exosome
.lysosomal lumen
.brush border membrane
  + 11 more...
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 661 114
2014-09-19protein level
1 545 114
2014-05-27protein level
1 544 114
2014-02-25protein level
1 540 114
2013-12-09protein level
1 453 114
2013-11-01protein level
1 445 114
2013-09-12protein level
1 445 114
2013-08-17protein level
1 445 114
2013-07-15protein level
1 332 113
2013-06-11protein level
1 332 113
2013-02-12protein level
1 186 113
2012-12-20protein level
1 185 113
2012-10-30protein level
1 204 113
2012-10-07protein level
1 204 114
2012-08-24protein level
1 155 114
2012-07-28protein level
1 154 114
2012-06-08protein level
1 156 114
2012-05-07protein level
1 156 114
2012-04-10protein level
1 156 114
2012-01-13protein level
1 71 114
2011-12-20protein level
1 71 114
2011-11-11protein level
1 71 114
2011-08-23protein level
1 71 114
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_O60494-1
136 0 0 398479.2813
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
bone13
brain4
embryonic tissue14
eye4
intestine12
kidney208
lung2
muscle18
pancreas4
placenta7
testis62
thymus12
thyroid42
trachea57
uterus8
Health State
TissuesTPM*
normal18
germ cell tumor3
head and neck tumor14
non-neoplasia10
pancreatic tumor9
primitive neuroectodermal tumor of the CNS7
uterine tumor22
Developmental Stage
TissuesTPM*
adult6
blastocyst16
fetus7
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
kidney115.5
ovary1.7
placenta1.7
small intestine35.5
testis2
thyroid gland2.5
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Disease
No.Disease DescriptionRef.
1(#261100, phenotype) Megaloblastic anemia 1OMIM
2(*602997, gene) Cubilin; CUBNOMIM


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