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> Protein (NX_O60884)
Protein (NX_O60884)
Protein
Gene SymbolDNAJA2 to neXtProt (NX_O60884)
DescriptionDnaJ homolog subfamily A member 2
Chromosome16
Location16q11.2 (46989299 ~ 47007699) to Ensembl
Sequene Features : Isoforms 1, Variants 28, PTMs 13 to neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.protein refolding
.response to heat
.positive regulation of cell proliferation
.chaperone binding
.unfolded protein binding
.metal ion binding
.ATP binding
.extracellular exosome
.membrane
.cytosol
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 28 13
2014-09-19protein level
1 24 13
2014-05-27protein level
1 24 13
2014-02-25protein level
1 24 11
2013-12-09protein level
1 20 11
2013-11-01protein level
1 18 7
2013-09-12protein level
1 18 7
2013-08-17protein level
1 18 7
2013-07-15protein level
1 11 3
2013-06-11protein level
1 11 3
2013-02-12protein level
1 5 3
2012-12-20protein level
1 5 3
2012-10-30protein level
1 5 3
2012-10-07protein level
1 5 3
2012-08-24protein level
1 1 3
2012-07-28protein level
1 1 3
2012-06-08protein level
1 7 3
2012-05-07protein level
1 7 3
2012-04-10protein level
1 7 3
2012-01-13protein level
1 9 3
2011-12-20protein level
1 9 3
2011-11-11protein level
1 9 3
2011-08-23protein level
1 9 3
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_O60884-1
17 0 0 45716.4607
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-352957,EBI-2555157 DNAJA4  
  .negative regulation of inclusion body assembly
.protein refolding
.response to heat
.chaperone binding
.unfolded protein binding
.metal ion binding
.ATP binding
.membrane
.cytosol
2 EBI-352957,EBI-3834328 AICDA  
  .negative regulation of methylation-dependent chromatin silencing
.DNA demethylation
.cellular response to lipopolysaccharide
  + 5 more...
.ubiquitin protein ligase binding
.zinc ion binding
.cytidine deaminase activity
.cytoplasm
.nucleus
3 EBI-352957,EBI-357298 NUDC  
  .cell division
.cell proliferation
.multicellular organismal development
  + 3 more...
.N/A .microtubule
.cytosol
.cytoplasm
.nucleoplasm
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adipose tissue77
adrenal gland60
ascites125
bladder66
blood106
bone195
bone marrow20
brain63
cervix20
connective tissue26
embryonic tissue46
esophagus99
eye52
heart44
intestine129
kidney28
larynx255
liver97
lung47
lymph22
lymph node55
mammary gland92
mouth90
muscle122
ovary78
pancreas28
pharynx49
pituitary gland60
placenta91
prostate63
salivary gland49
skin61
spleen93
stomach20
testis124
thymus50
thyroid150
trachea57
uterus112
vascular38
Health State
TissuesTPM*
normal70
adrenal tumor79
breast (mammary gland) tumor85
chondrosarcoma60
colorectal tumor204
esophageal tumor115
gastrointestinal tumor50
germ cell tumor121
glioma9
head and neck tumor141
kidney tumor29
leukemia74
liver tumor135
lung tumor19
lymphoma41
non-neoplasia20
ovarian tumor105
pancreatic tumor9
primitive neuroectodermal tumor of the CNS39
prostate cancer77
retinoblastoma43
skin tumor71
soft tissue/muscle tissue tumor55
uterine tumor188
Developmental Stage
TissuesTPM*
adult88
embryoid body57
blastocyst81
neonate64
fetus53
infant85
juvenile89
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue34.9
adrenal gland43.8
appendix31.2
bone marrow30.3
cerebral cortex40.9
colon36.7
duodenum32.4
esophagus46
gallbladder36
heart muscle57.6
kidney39.8
liver36.7
lung28.9
lymph node41.3
ovary36
pancreas13.2
placenta33.1
prostate35.4
salivary gland23.1
skin30.2
small intestine31.2
spleen34.2
stomach30.4
testis48.4
thyroid gland39.4
urinary bladder42.3
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*611322, gene) Dnaj/hsp40 homolog, subfamily a, member 2; DNAJA2OMIM


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