Home| Contact Us

HOME SEARCH STATISTICS
> Protein (NX_O75052)
Protein (NX_O75052)
Protein
Gene SymbolNOS1AP to neXtProt (NX_O75052)
DescriptionCarboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein
Chromosome1
Location1q23.3 (162039564 ~ 162353321) to Ensembl
Sequene Features : Isoforms 3, Variants 69, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.positive regulation of peptidyl-cysteine S-nitrosylation
.positive regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization
.regulation of generation of L-type calcium current
  + 13 more...
.nitric-oxide synthase binding .perinuclear region of cytoplasm
.sarcoplasmic reticulum membrane
.Z disc
  + 3 more...
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
3 69 6
2014-09-19protein level
3 49 6
2014-05-27protein level
3 49 6
2014-02-25protein level
3 47 6
2013-12-09protein level
3 43 6
2013-11-01protein level
3 39 6
2013-09-12protein level
3 39 5
2013-08-17protein level
3 39 5
2013-07-15protein level
3 26 5
2013-06-11protein level
3 26 5
2013-02-12protein level
3 9 12
2012-12-20protein level
3 8 12
2012-10-30protein level
3 10 12
2012-10-07protein level
3 10 5
2012-08-24protein level
3 10 5
2012-07-28protein level
3 10 5
2012-06-08protein level
3 11 5
2012-05-07protein level
3 5 5
2012-04-10protein level
2 5 5
2012-01-13protein level
1 4 5
2011-12-20protein level
1 4 5
2011-11-11protein level
1 4 5
2011-08-23protein level
1 4 5
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_O75052-1
0 27 0 56114.6287
NX_O75052-2
1 10 0 22940.6268
NX_O75052-3
0 27 0 55534.2357
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-780467,EBI-10268158 FAM133A  
  .N/A .N/A .N/A
2 EBI-780467,EBI-3650647 TRAF4  
  .positive regulation of protein homodimerization activity
.positive regulation of JNK cascade
.positive regulation of protein kinase activity
  + 6 more...
.WW domain binding
.thioesterase binding
.ubiquitin protein ligase binding
  + 4 more...
.perinuclear region of cytoplasm
.tight junction
.plasma membrane
  + 3 more...
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
bone13
brain14
embryonic tissue4
eye14
intestine4
kidney14
liver9
mammary gland19
placenta3
testis16
Health State
TissuesTPM*
normal8
colorectal tumor8
glioma9
kidney tumor43
liver tumor20
Developmental Stage
TissuesTPM*
adult5
fetus7
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue1.1
adrenal gland3.3
bone marrow1.2
cerebral cortex13.6
colon2.8
duodenum1.6
esophagus1.4
gallbladder2.1
heart muscle1.1
kidney3.1
lung1.4
prostate1.6
salivary gland3
small intestine1.9
stomach1.8
testis2.1
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*605551, gene) Nitric oxide synthase 1 (neuronal) adaptor protein; NOS1APOMIM
2(%610141, phenotype) Qt interval, variation inOMIM


#424, YPRC/BPRC, Industry-University Research Center, Yonsei Univ., Seodaemun-gu, Seoul, Korea, 120-749
Tel: +82-2-2123-6626, Fax: +82-2-393-6589
2014-2019 (C) Yonsei Proteome Research Center