Home| Contact Us

HOME SEARCH STATISTICS
> Protein (NX_O75081)
Protein (NX_O75081)
Protein
Gene SymbolCBFA2T3 to neXtProt (NX_O75081)
DescriptionProtein CBFA2T3
Chromosome16
Location16q24.3 (88941266 ~ 89043612) to Ensembl
Sequene Features : Isoforms 4, Variants 95, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.positive regulation of transcription from RNA polymerase II promoter
.negative regulation of transcription, DNA-templated
.granulocyte differentiation
  + 2 more...
.metal ion binding
.transcription corepressor activity
.sequence-specific DNA binding transcription factor activity
.chromatin binding
.nucleolus
.nucleoplasm
.nucleus
.Golgi membrane
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
4 95 1
2014-09-19protein level
4 73 1
2014-05-27protein level
4 73 1
2014-02-25protein level
4 72 1
2013-12-09protein level
4 46 1
2013-11-01protein level
4 46 1
2013-09-12protein level
4 46 1
2013-08-17protein level
4 46 1
2013-07-15protein level
4 31 1
2013-06-11protein level
4 31 1
2013-02-12protein level
4 20 9
2012-12-20protein level
4 19 9
2012-10-30protein level
4 23 9
2012-10-07protein level
4 23 3
2012-08-24protein level
4 22 3
2012-07-28protein level
4 22 3
2012-06-08protein level
4 11 3
2012-05-07protein level
4 11 3
2012-04-10protein level
4 11 3
2012-01-13protein level
4 11 3
2011-12-20protein level
4 11 3
2011-11-11protein level
4 11 3
2011-08-23protein level
5 11 3
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_O75081-1
5 21 4 71147.349
NX_O75081-2
2 20 4 62333.0167
NX_O75081-4
1 21 4 63081.3644
NX_O75081-5
1 1 0 7431.7125
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-1190217,EBI-7135904 PLXNA3  
  .semaphorin-plexin signaling pathway involved in axon guidance
.semaphorin-plexin signaling pathway
.positive regulation of cytoskeleton organization
  + 9 more...
.semaphorin receptor activity
.transmembrane signaling receptor activity
.integral component of membrane
.membrane
.plasma membrane
  + 2 more...
2 EBI-1190217,EBI-1190229 ZNF652  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.DNA binding
.nucleus
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
ascites25
blood32
bone marrow61
brain10
cervix20
eye28
intestine8
kidney4
liver29
lung2
lymph135
lymph node33
mammary gland6
muscle9
ovary9
pancreas14
placenta3
spleen37
testis13
thymus62
tonsil117
uterus4
Health State
TissuesTPM*
normal15
breast (mammary gland) tumor10
gastrointestinal tumor8
germ cell tumor15
kidney tumor14
leukemia63
lymphoma124
ovarian tumor13
pancreatic tumor28
retinoblastoma21
soft tissue/muscle tissue tumor7
Developmental Stage
TissuesTPM*
adult12
fetus28
juvenile71
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue7.3
adrenal gland1.1
appendix9.1
bone marrow4.7
cerebral cortex3.6
colon4.3
duodenum3.4
esophagus2.2
gallbladder2.8
heart muscle4.4
liver2.4
lung6.4
lymph node11.1
pancreas12.7
placenta3.8
prostate4.6
salivary gland2.7
skin3.4
small intestine5.5
spleen16.3
stomach4.2
testis4.1
thyroid gland1.5
urinary bladder5.2
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Disease
No.Disease DescriptionRef.
1(*603870, gene) Core-binding factor, alpha subunit 2, translocated to, 3; CBFA2T3OMIM
2acute myelogenous leukemiaCGP


#424, YPRC/BPRC, Industry-University Research Center, Yonsei Univ., Seodaemun-gu, Seoul, Korea, 120-749
Tel: +82-2-2123-6626, Fax: +82-2-393-6589
2014-2019 (C) Yonsei Proteome Research Center