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> Protein (NX_O75128)
Protein (NX_O75128)
Protein
Gene SymbolCOBL to neXtProt (NX_O75128)
DescriptionProtein cordon-bleu
Chromosome7
Location7p12.1 (51083909 ~ 51384515) to Ensembl
Sequene Features : Isoforms 7, Variants 217, PTMs 10 to neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.positive regulation of ruffle assembly
.positive regulation of dendrite development
.actin filament network formation
  + 9 more...
.actin monomer binding .perinuclear region of cytoplasm
.axonal growth cone
.dendritic growth cone
  + 7 more...
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
7 217 10
2014-09-19protein level
7 170 10
2014-05-27protein level
7 170 10
2014-02-25protein level
7 168 10
2013-12-09protein level
7 127 10
2013-11-01protein level
7 123 10
2013-09-12protein level
7 123 11
2013-08-17protein level
7 123 11
2013-07-15protein level
7 91 11
2013-06-11protein level
7 91 11
2013-02-12protein level
7 57 28
2012-12-20protein level
7 59 28
2012-10-30protein level
7 71 28
2012-10-07protein level
7 71 6
2012-08-24protein level
7 55 6
2012-07-28protein level
7 53 6
2012-06-08protein level
7 9 6
2012-05-07protein level
7 9 6
2012-04-10protein level
7 9 6
2012-01-13protein level
7 9 6
2011-12-20protein level
7 23 6
2011-11-11protein level
7 23 5
2011-08-23protein level
7 23 5
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_O75128-1
0 62 0 135533.0955
NX_O75128-2
2 63 0 143839.2778
NX_O75128-3
0 60 0 130801.7168
NX_O75128-4
6 16 0 51162.7669
NX_O75128-5
1 16 0 41593.8928
NX_O75128-6
1 43 0 85796.6864
NX_O75128-7
0 62 0 136597.7066
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adrenal gland30
bladder33
bone13
brain49
cervix247
ear62
embryonic tissue4
eye28
heart22
intestine17
kidney4
liver19
lung17
lymph node11
mammary gland33
mouth60
muscle28
ovary9
pancreas56
parathyroid145
placenta14
prostate36
salivary gland49
skin4
testis4
thyroid21
trachea19
uterus30
Health State
TissuesTPM*
normal32
breast (mammary gland) tumor32
cervical tumor231
colorectal tumor35
germ cell tumor15
glioma46
head and neck tumor7
liver tumor10
lung tumor9
non-neoplasia62
pancreatic tumor28
primitive neuroectodermal tumor of the CNS7
prostate cancer57
retinoblastoma21
uterine tumor44
Developmental Stage
TissuesTPM*
adult35
blastocyst16
fetus28
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue2.1
adrenal gland1.4
appendix2
cerebral cortex35.2
colon12.3
duodenum19.7
esophagus17.5
gallbladder8.1
heart muscle37.9
kidney14.1
liver15.1
lung20.2
ovary4
pancreas11
placenta6.7
prostate14.8
salivary gland40
skin14.4
small intestine20.9
stomach11
testis5
thyroid gland11.2
Tissues
TissuesExpression level
adrenal glandHigh
appendixHigh
bone marrowMedium
breastHigh
bronchusMedium
cerebellumMedium
cerebral cortexLow
cervix, uterineHigh
colonHigh
duodenumHigh
endometrium 1High
endometrium 2High
epididymisMedium
esophagusHigh
fallopian tubeMedium
gallbladderHigh
heart muscleMedium
hippocampusLow
kidneyHigh
lateral ventricleLow
liverMedium
lungMedium
lymph nodeHigh
nasopharynxMedium
oral mucosaMedium
ovaryMedium
pancreasHigh
parathyroid glandHigh
placentaHigh
prostateHigh
rectumHigh
salivary glandMedium
seminal vesicleHigh
skeletal muscleMedium
skin 1Medium
skin 2Medium
small intestineHigh
smooth muscleLow
soft tissue 1Medium
soft tissue 2Medium
spleenHigh
stomach 1High
stomach 2High
testisHigh
thyroid glandMedium
tonsilHigh
urinary bladderHigh
vaginaMedium
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Expression level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*610317, gene) Cordon-bleu, mouse, homolog of; COBLOMIM


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