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> Protein (NX_O75143)
Protein (NX_O75143)
Protein
Gene SymbolATG13 to neXtProt (NX_O75143)
DescriptionAutophagy-related protein 13
Chromosome11
Location11p11.2 (46638826 ~ 46696368) to Ensembl
Sequene Features : Isoforms 5, Variants 61, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.positive regulation of protein targeting to mitochondrion
.activation of mitophagy in response to mitochondrial depolarization
.autophagic vacuole assembly
.protein kinase binding .ULK1-ATG13-FIP200 complex
.ATG1/UKL1 signaling complex
.cytosol
  + 2 more...
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
5 61 3
2014-09-19protein level
5 46 3
2014-05-27protein level
5 46 3
2014-02-25protein level
5 46 3
2013-12-09protein level
5 31 3
2013-11-01protein level
5 30 3
2013-09-12protein level
5 30 3
2013-08-17protein level
5 30 3
2013-07-15protein level
5 23 2
2013-06-11protein level
5 23 2
2013-02-12protein level
5 11 9
2012-12-20protein level
5 12 6
2012-10-30protein level
3 9 6
2012-10-07protein level
3 9 2
2012-08-24protein level
3 8 2
2012-07-28protein level
3 9 2
2012-06-08protein level
3 8 2
2012-05-07protein level
3 8 2
2012-04-10protein level
3 8 2
2012-01-13protein level
3 6 2
2011-12-20protein level
3 6 2
2011-11-11protein level
3 6 2
2011-08-23protein level
3 6 2
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_O75143-1
1 23 0 56535.9009
NX_O75143-2
0 23 0 52788.9947
NX_O75143-3
1 19 0 44458.0971
NX_O75143-4
1 17 0 44064.4248
NX_O75143-5
3 23 0 60116.7231
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-2798775,EBI-908831 ULK1  
  .regulation of neurotrophin TRK receptor signaling pathway
.axon extension
.negative regulation of collateral sprouting
  + 15 more...
.protein complex binding
.Rab GTPase binding
.ATP binding
.protein serine/threonine kinase activity
.extrinsic component of autophagic vacuole membrane
.extrinsic component of pre-autophagosomal structure membrane
.extrinsic component of omegasome membrane
  + 9 more...
2 EBI-2798775,EBI-720116 GABARAPL2  
  .negative regulation of proteasomal protein catabolic process
.membrane fusion
.nucleophagy
  + 7 more...
.ATPase binding
.GABA receptor binding
.beta-tubulin binding
  + 2 more...
.cytoplasmic vesicle
.extrinsic component of membrane
.cytosol
  + 7 more...
3 EBI-2798775,EBI-1047793 RB1CC1  
  .negative regulation of extrinsic apoptotic signaling pathway
.positive regulation of cell size
.regulation of autophagy
  + 8 more...
.protein kinase binding .ULK1-ATG13-FIP200 complex
.ATG1/UKL1 signaling complex
.pre-autophagosomal structure membrane
  + 3 more...
4 EBI-2798775,EBI-2946739 ATG101  
  .autophagic vacuole assembly .identical protein binding
.protein complex binding
.pre-autophagosomal structure
5 EBI-2798775,EBI-373144 MAP1LC3B  
  .regulation of mitochondrion degradation
.membrane fusion
.nucleophagy
  + 3 more...
.microtubule binding .cytoplasmic vesicle
.organelle membrane
.extrinsic component of membrane
  + 9 more...
6 EBI-2798775,EBI-746969 GABARAPL1  
  .membrane fusion
.nucleophagy
.mitochondrion degradation
.autophagic vacuole assembly
.GABA receptor binding
.beta-tubulin binding
.Tat protein binding
.microtubule binding
.cell body
.dendrite cytoplasm
.dendrite membrane
  + 10 more...
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
ascites100
bladder66
blood89
bone55
bone marrow102
brain345
cervix164
connective tissue147
embryonic tissue122
esophagus148
eye162
heart55
intestine163
kidney90
larynx170
liver48
lung113
lymph225
lymph node44
mammary gland99
mouth302
muscle56
ovary98
pancreas70
parathyroid97
pharynx49
pituitary gland121
placenta95
prostate131
salivary gland49
skin118
spleen224
stomach156
testis367
thymus414
thyroid150
tonsil58
trachea617
umbilical cord435
uterus193
vascular232
Health State
TissuesTPM*
normal186
breast (mammary gland) tumor85
cervical tumor115
chondrosarcoma108
colorectal tumor222
esophageal tumor173
gastrointestinal tumor126
germ cell tumor224
glioma139
head and neck tumor231
kidney tumor87
leukemia105
liver tumor72
lung tumor155
lymphoma180
non-neoplasia175
ovarian tumor131
pancreatic tumor133
primitive neuroectodermal tumor of the CNS86
prostate cancer154
retinoblastoma279
skin tumor47
soft tissue/muscle tissue tumor103
uterine tumor133
Developmental Stage
TissuesTPM*
adult128
embryoid body71
blastocyst211
neonate321
fetus156
infant127
juvenile125
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue23.9
adrenal gland27
appendix24.4
bone marrow37.4
cerebral cortex34
colon22.7
duodenum22.9
esophagus25
gallbladder27.3
heart muscle25.3
kidney24
liver13.1
lung22.8
lymph node27.1
ovary28.8
pancreas18.3
placenta21.9
prostate24
salivary gland22.7
skin20.9
small intestine21.6
spleen25.9
stomach28.7
testis61.5
thyroid gland39.4
urinary bladder29.7
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected


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