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> Protein (NX_O75182)
Protein (NX_O75182)
Protein
Gene SymbolSIN3B to neXtProt (NX_O75182)
DescriptionPaired amphipathic helix protein Sin3b
Chromosome19
Location19p13.11 (16940211 ~ 16991164) to Ensembl
Sequene Features : Isoforms 3, Variants 99, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.cardiac muscle tissue development
.small molecule metabolic process
.cellular lipid metabolic process
  + 3 more...
.chromatin binding
.RNA polymerase II transcription corepressor activity
.autosome
.Sin3 complex
.cytoplasm
  + 5 more...
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
3 99 2
2014-09-19protein level
3 76 2
2014-05-27protein level
3 76 3
2014-02-25protein level
3 76 3
2013-12-09protein level
3 63 3
2013-11-01protein level
3 58 3
2013-09-12protein level
3 58 3
2013-08-17protein level
3 58 3
2013-07-15protein level
3 37 3
2013-06-11protein level
3 37 3
2013-02-12protein level
3 13 0
2012-12-20protein level
3 13 0
2012-10-30protein level
3 17 0
2012-10-07protein level
3 17 0
2012-08-24protein level
3 17 0
2012-07-28protein level
3 17 0
2012-06-08protein level
3 17 0
2012-05-07protein level
3 12 0
2012-04-10protein level
3 12 0
2012-01-13protein level
3 7 0
2011-12-20protein level
3 7 0
2011-11-11protein level
3 7 0
2011-08-23protein level
3 7 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_O75182-1
2 52 1 132982.7362
NX_O75182-2
0 52 2 129278.0931
NX_O75182-3
1 17 0 39482.0874
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-540462,EBI-447544 MYC  
  .positive regulation of response to DNA damage stimulus
.positive regulation of DNA biosynthetic process
.positive regulation of metanephric cap mesenchymal cell proliferation
  + 36 more...
.E-box binding
.repressing transcription factor binding
.protein complex binding
  + 5 more...
.protein complex
.cytosol
.nucleolus
  + 2 more...
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
ascites50
bladder33
blood40
bone13
brain52
cervix82
connective tissue40
embryonic tissue98
esophagus49
eye43
heart67
intestine8
kidney23
liver34
lung32
lymph22
lymph node122
mammary gland46
mouth30
muscle18
nerve128
ovary39
pancreas18
parathyroid48
pituitary gland60
placenta113
prostate26
skin52
spleen37
testis80
thymus37
tonsil58
trachea19
uterus60
Health State
TissuesTPM*
normal62
bladder carcinoma56
breast (mammary gland) tumor21
cervical tumor57
chondrosarcoma60
esophageal tumor57
gastrointestinal tumor25
germ cell tumor22
glioma46
head and neck tumor14
kidney tumor58
leukemia31
liver tumor41
lung tumor9
lymphoma55
non-neoplasia20
ovarian tumor39
pancreatic tumor38
primitive neuroectodermal tumor of the CNS15
prostate cancer28
retinoblastoma21
skin tumor63
soft tissue/muscle tissue tumor39
uterine tumor66
Developmental Stage
TissuesTPM*
adult58
embryoid body128
blastocyst146
fetus70
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue25
adrenal gland21.6
appendix25.7
bone marrow11.4
cerebral cortex27.1
colon12.6
duodenum14.3
esophagus15.8
gallbladder20.4
heart muscle13.3
kidney15.8
liver6.2
lung23.7
lymph node25.5
ovary34
pancreas9.5
placenta34.6
prostate28.8
salivary gland18.5
skin24.5
small intestine17.5
spleen40.8
stomach17.3
testis44.4
thyroid gland15.7
urinary bladder17.7
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*607777, gene) Sin3, yeast, homolog of, b; SIN3BOMIM


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