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> Protein (NX_O75223)
Protein (NX_O75223)
Protein
Gene SymbolGGCT to neXtProt (NX_O75223)
DescriptionGamma-glutamylcyclotransferase
Chromosome7
Location7p14.3 (30536237 ~ 30591095) to Ensembl
Sequene Features : Isoforms 4, Variants 25, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.glutathione derivative biosynthetic process
.small molecule metabolic process
.xenobiotic metabolic process
  + 2 more...
.protein homodimerization activity
.gamma-glutamylcyclotransferase activity
.extracellular exosome
.cytosol
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
4 25 2
2014-09-19protein level
4 20 2
2014-05-27protein level
4 19 2
2014-02-25protein level
4 19 2
2013-12-09protein level
4 14 2
2013-11-01protein level
4 14 1
2013-09-12protein level
4 14 0
2013-08-17protein level
4 14 0
2013-07-15protein level
4 8 0
2013-06-11protein level
4 8 0
2013-02-12protein level
2 3 0
2012-12-20protein level
2 3 0
2012-10-30protein level
2 3 0
2012-10-07protein level
2 3 0
2012-08-24protein level
2 2 0
2012-07-28protein level
2 2 0
2012-06-08protein level
2 6 0
2012-05-07protein level
2 6 0
2012-04-10protein level
2 6 0
2012-01-13protein level
2 8 0
2011-12-20protein level
2 8 0
2011-11-11protein level
2 8 0
2011-08-23protein level
2 8 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_O75223-1
3 7 0 20994.275
NX_O75223-2
1 4 0 12934.3189
NX_O75223-3
1 5 0 10497.1804
NX_O75223-4
3 4 0 19079.3555
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adipose tissue155
ascites75
bladder368
blood49
bone69
bone marrow123
brain17
connective tissue214
embryonic tissue37
eye28
heart22
intestine38
kidney75
larynx42
liver77
lung38
lymph22
lymph node11
mammary gland79
mouth15
muscle84
ovary29
pancreas65
pharynx24
pituitary gland121
placenta10
prostate68
salivary gland690
skin223
stomach52
testis11
thyroid21
tonsil58
uterus60
Health State
TissuesTPM*
normal40
bladder carcinoma568
breast (mammary gland) tumor107
chondrosarcoma24
colorectal tumor53
gastrointestinal tumor42
germ cell tumor18
glioma9
head and neck tumor22
kidney tumor101
leukemia84
liver tumor72
lung tumor19
lymphoma41
ovarian tumor26
pancreatic tumor38
primitive neuroectodermal tumor of the CNS62
prostate cancer77
retinoblastoma64
skin tumor55
soft tissue/muscle tissue tumor335
uterine tumor33
Developmental Stage
TissuesTPM*
adult53
embryoid body42
blastocyst16
fetus19
juvenile17
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue42.7
adrenal gland30.2
appendix34.6
bone marrow24
cerebral cortex30.4
colon49.7
duodenum38.1
esophagus53
gallbladder33.9
heart muscle19.2
kidney34.2
liver24
lung20.3
lymph node31.4
ovary17.3
pancreas13.3
placenta36.8
prostate34.3
salivary gland30.2
skin60.2
small intestine28.4
spleen16.3
stomach27.5
testis15
thyroid gland27.5
urinary bladder36.9
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*137170, gene) Gamma-glutamyl cyclotransferase; GGCTOMIM


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