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> Protein (NX_O75339)
Protein (NX_O75339)
Protein
Gene SymbolCILP to neXtProt (NX_O75339)
DescriptionCartilage intermediate layer protein 1
Chromosome15
Location15q22.31 (65488337 ~ 65503826) to Ensembl
Sequene Features : Isoforms 1, Variants 204, PTMs 19 to neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.negative regulation of insulin-like growth factor receptor signaling pathway .N/A .extracellular exosome
.extracellular matrix
.extracellular space
.proteinaceous extracellular matrix
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 204 19
2014-09-19protein level
1 158 19
2014-05-27protein level
1 157 19
2014-02-25protein level
1 157 19
2013-12-09protein level
1 122 19
2013-11-01protein level
1 112 19
2013-09-12protein level
1 112 19
2013-08-17protein level
1 112 19
2013-07-15protein level
1 80 12
2013-06-11protein level
1 80 12
2013-02-12protein level
1 55 12
2012-12-20protein level
1 55 12
2012-10-30protein level
1 58 12
2012-10-07protein level
1 58 12
2012-08-24protein level
1 45 12
2012-07-28protein level
1 45 12
2012-06-08protein level
1 49 12
2012-05-07protein level
1 48 12
2012-04-10protein level
1 48 12
2012-01-13protein level
1 25 12
2011-12-20protein level
1 25 12
2011-11-11protein level
1 25 12
2011-08-23protein level
1 25 12
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_O75339-1
58 0 0 132479.6208
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
connective tissue429
eye4
heart33
intestine4
liver4
lung2
mammary gland26
mouth30
muscle65
ovary68
pancreas23
placenta3
prostate10
stomach20
testis68
trachea173
umbilical cord72
uterus68
Health State
TissuesTPM*
normal11
breast (mammary gland) tumor21
chondrosarcoma24
germ cell tumor3
head and neck tumor7
non-neoplasia579
ovarian tumor65
pancreatic tumor47
Developmental Stage
TissuesTPM*
adult37
neonate32
fetus8
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue38.7
appendix11.7
colon9.3
duodenum2.6
esophagus13.2
gallbladder49.7
heart muscle26.8
lymph node1.9
ovary5.7
pancreas1.5
placenta3.3
prostate3.4
salivary gland1.6
skin1.7
small intestine3.4
stomach1.1
testis19.8
thyroid gland3.5
urinary bladder30.5
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*603489, gene) Cartilage intermediate layer protein; CILPOMIM
2(#603932, phenotype) Intervertebral disc disease; IDDOMIM


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