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> Protein (NX_O75346)
Protein (NX_O75346)
Protein
Gene SymbolZNF253 to neXtProt (NX_O75346)
DescriptionZinc finger protein 253
Chromosome19
Location19p12 (19976695 ~ 20005483) to Ensembl
Sequene Features : Isoforms 2, Variants 54, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.negative regulation of transcription, DNA-templated
.regulation of transcription, DNA-templated
.transcription, DNA-templated
.zinc ion binding
.DNA binding
.nucleus
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01transcript level
2 54 0
2014-09-19transcript level
2 42 0
2014-05-27transcript level
2 42 1
2014-02-25transcript level
2 41 1
2013-12-09transcript level
2 31 1
2013-11-01transcript level
2 31 1
2013-09-12transcript level
2 31 1
2013-08-17transcript level
2 31 1
2013-07-15transcript level
2 21 0
2013-06-11transcript level
2 21 0
2013-02-12transcript level
2 5 0
2012-12-20transcript level
2 4 0
2012-10-30transcript level
2 6 0
2012-10-07transcript level
2 6 0
2012-08-24transcript level
2 6 0
2012-07-28transcript level
2 6 0
2012-06-08transcript level
2 9 0
2012-05-07transcript level
2 8 0
2012-04-10transcript level
2 8 0
2012-01-13transcript level
2 8 0
2011-12-20transcript level
2 8 0
2011-11-11transcript level
2 8 0
2011-08-23transcript level
2 8 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_O75346-1
2 12 15 57564.6371
NX_O75346-2
1 12 13 48714.1386
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
bone13
bone marrow41
brain35
connective tissue13
embryonic tissue32
eye14
intestine21
kidney14
liver9
lung5
lymph node44
mammary gland33
mouth15
muscle9
ovary9
pancreas18
prostate10
salivary gland98
skin14
spleen56
testis43
thymus75
trachea57
uterus8
vascular38
Health State
TissuesTPM*
normal22
breast (mammary gland) tumor42
gastrointestinal tumor33
germ cell tumor75
head and neck tumor7
kidney tumor29
liver tumor10
lung tumor9
non-neoplasia20
ovarian tumor13
prostate cancer9
retinoblastoma64
soft tissue/muscle tissue tumor7
Developmental Stage
TissuesTPM*
adult18
embryoid body14
blastocyst48
neonate32
fetus41
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue3
adrenal gland5.5
appendix5
bone marrow1.6
cerebral cortex6.6
colon5.4
duodenum4.3
esophagus3.6
gallbladder4.2
heart muscle4.5
kidney7.3
liver2.7
lung3.7
lymph node9.6
ovary13.6
pancreas2.4
placenta3.9
prostate5.8
salivary gland3.8
skin4
small intestine4.5
spleen6.8
stomach5.6
testis4.3
thyroid gland16
urinary bladder9.8
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Disease
No.Disease DescriptionRef.
1(*606954, gene) Zinc finger protein 253; ZNF253OMIM


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