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> Protein (NX_O75356)
Protein (NX_O75356)
Protein
Gene SymbolENTPD5 to neXtProt (NX_O75356)
DescriptionEctonucleoside triphosphate diphosphohydrolase 5
Chromosome14
Location14q24.3 (74424713 ~ 74486102) to Ensembl
Sequene Features : Isoforms 1, Variants 39, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.'de novo' posttranslational protein folding
.ATP metabolic process
.positive regulation of glycolytic process
  + 4 more...
.uridine-diphosphatase activity
.guanosine-diphosphatase activity
.extracellular exosome
.endoplasmic reticulum
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 39 4
2014-09-19protein level
1 29 4
2014-05-27protein level
1 29 4
2014-02-25protein level
1 29 4
2013-12-09protein level
1 22 2
2013-11-01protein level
1 19 2
2013-09-12protein level
1 19 2
2013-08-17protein level
1 19 2
2013-07-15protein level
1 15 2
2013-06-11protein level
1 15 2
2013-02-12protein level
1 11 2
2012-12-20protein level
1 11 2
2012-10-30protein level
1 14 3
2012-10-07protein level
1 14 3
2012-08-24protein level
1 11 3
2012-07-28protein level
1 11 3
2012-06-08protein level
1 11 3
2012-05-07protein level
1 11 3
2012-04-10protein level
1 11 3
2012-01-13protein level
1 7 3
2011-12-20protein level
1 7 3
2011-11-11protein level
1 7 3
2011-08-23protein level
1 7 3
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_O75356-1
18 0 0 47486.8413
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-7416931,EBI-752241 MXI1  
  .cytoplasmic sequestering of transcription factor
.negative regulation of cell proliferation
.transcription, DNA-templated
.negative regulation of transcription from RNA polymerase II promoter
.transcription corepressor activity
.DNA binding
.cytoplasm
.nucleolus
.nucleus
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
blood8
bone13
brain2
cervix20
embryonic tissue18
esophagus49
eye19
intestine38
kidney71
liver43
lung8
lymph22
lymph node22
mammary gland19
mouth30
muscle9
nerve64
ovary9
placenta10
prostate15
skin4
stomach10
testis9
trachea57
Health State
TissuesTPM*
normal15
breast (mammary gland) tumor32
cervical tumor28
chondrosarcoma12
colorectal tumor53
esophageal tumor57
gastrointestinal tumor8
germ cell tumor7
head and neck tumor14
leukemia10
liver tumor62
lymphoma13
ovarian tumor13
retinoblastoma21
skin tumor7
Developmental Stage
TissuesTPM*
adult13
embryoid body14
blastocyst48
fetus17
juvenile17
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue7.3
adrenal gland6.3
appendix12
bone marrow4.4
cerebral cortex5.1
colon85.4
duodenum63.3
esophagus11.4
gallbladder13.2
heart muscle5.7
kidney70.8
liver136.6
lung6.1
lymph node5
ovary6.2
pancreas1.8
placenta4.8
prostate39.8
salivary gland6.1
skin6
small intestine59.6
spleen5.5
stomach36.3
testis9.6
thyroid gland6.2
urinary bladder19.7
Tissues
TissuesExpression level
adrenal glandMedium
appendixHigh
bone marrowLow
breastHigh
bronchusMedium
cerebellumLow
cerebral cortexLow
cervix, uterineLow
colonHigh
duodenumHigh
endometrium 1Low
endometrium 2Low
epididymisLow
esophagusLow
fallopian tubeMedium
gallbladderMedium
hippocampusLow
kidneyHigh
lateral ventricleLow
liverHigh
lungLow
lymph nodeLow
nasopharynxMedium
oral mucosaLow
pancreasMedium
parathyroid glandLow
placentaMedium
prostateHigh
rectumHigh
salivary glandLow
seminal vesicleLow
skin 1Low
skin 2Low
small intestineMedium
stomach 1Medium
stomach 2High
testisLow
thyroid glandMedium
tonsilLow
urinary bladderHigh
vaginaLow
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Expression level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*603162, gene) Ectonucleoside triphosphate diphosphohydrolase 5; ENTPD5OMIM


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