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> Protein (NX_O75431)
Protein (NX_O75431)
Protein
Gene SymbolMTX2 to neXtProt (NX_O75431)
DescriptionMetaxin-2
Chromosome2
Location2q31.1 (177134123 ~ 177202753) to Ensembl
Sequene Features : Isoforms 2, Variants 30, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.cellular protein metabolic process
.mitochondrial transport
.protein targeting to mitochondrion
.N/A .mitochondrial outer membrane
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
2 30 0
2014-09-19protein level
2 27 0
2014-05-27protein level
2 27 0
2014-02-25protein level
1 27 0
2013-12-09protein level
1 20 0
2013-11-01protein level
1 20 0
2013-09-12protein level
1 20 0
2013-08-17protein level
1 20 0
2013-07-15protein level
1 15 0
2013-06-11protein level
1 15 0
2013-02-12protein level
1 6 0
2012-12-20protein level
1 6 0
2012-10-30protein level
1 10 0
2012-10-07protein level
1 10 0
2012-08-24protein level
1 10 0
2012-07-28protein level
1 10 0
2012-06-08protein level
1 11 0
2012-05-07protein level
1 7 0
2012-04-10protein level
1 7 0
2012-01-13protein level
1 1 0
2011-12-20protein level
1 1 0
2011-11-11protein level
1 1 0
2011-08-23protein level
1 1 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_O75431-1
1 11 0 29743.9859
NX_O75431-2
1 11 0 28804.4861
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-7415268,EBI-742268 TADA2A  
  .histone H3 acetylation
.transcription from RNA polymerase II promoter
.regulation of transcription from RNA polymerase II promoter
.chromatin organization
.zinc ion binding
.transcription cofactor activity
.sequence-specific DNA binding transcription factor activity
  + 2 more...
.chromosome
.nucleus
.PCAF complex
2 EBI-7415268,EBI-749265 CCDC155  
  .chromosome localization to nuclear envelope involved in homologous chromosome segregation
.oogenesis
.spermatogenesis
  + 2 more...
.N/A .integral component of membrane
.nuclear outer membrane
.lateral element
.chromosome, telomeric region
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adrenal gland30
ascites50
bladder33
blood8
bone13
brain23
cervix20
connective tissue40
ear62
embryonic tissue56
esophagus49
eye43
heart22
intestine12
kidney61
liver4
lung44
lymph45
mammary gland39
muscle65
ovary49
pancreas18
placenta7
prostate26
skin23
stomach52
testis78
thymus12
uterus51
vascular19
Health State
TissuesTPM*
normal29
breast (mammary gland) tumor42
cervical tumor28
chondrosarcoma12
colorectal tumor8
esophageal tumor57
gastrointestinal tumor50
germ cell tumor41
kidney tumor43
leukemia21
lung tumor58
lymphoma69
non-neoplasia20
ovarian tumor52
primitive neuroectodermal tumor of the CNS31
prostate cancer28
retinoblastoma64
skin tumor39
soft tissue/muscle tissue tumor119
uterine tumor44
Developmental Stage
TissuesTPM*
adult27
embryoid body71
blastocyst81
fetus26
juvenile17
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue18.1
adrenal gland38.8
appendix16.6
bone marrow8.8
cerebral cortex24.2
colon29.4
duodenum23.2
esophagus25.6
gallbladder18.7
heart muscle42.1
kidney35.9
liver16.3
lung17
lymph node16.7
ovary18.3
pancreas11.7
placenta22.1
prostate25.6
salivary gland16.6
skin16.8
small intestine18.9
spleen12.4
stomach20.3
testis59.1
thyroid gland23.6
urinary bladder28.5
Tissues
TissuesExpression level
adrenal glandHigh
appendixMedium
bone marrowLow
breastMedium
bronchusMedium
cerebellumMedium
cerebral cortexMedium
cervix, uterineLow
colonMedium
duodenumMedium
endometrium 1Low
endometrium 2Low
epididymisLow
esophagusLow
fallopian tubeMedium
gallbladderMedium
heart muscleHigh
hippocampusMedium
kidneyMedium
lateral ventricleMedium
liverLow
lungMedium
lymph nodeLow
nasopharynxMedium
oral mucosaLow
ovaryLow
pancreasMedium
parathyroid glandHigh
placentaMedium
prostateMedium
rectumMedium
salivary glandMedium
seminal vesicleMedium
skeletal muscleMedium
skin 1Medium
skin 2Low
small intestineMedium
smooth muscleLow
soft tissue 1Low
soft tissue 2Low
spleenLow
stomach 1Low
stomach 2Low
testisMedium
thyroid glandLow
tonsilMedium
urinary bladderMedium
vaginaLow
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Expression level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*608555, gene) Metaxin 2; MTX2OMIM


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