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> Protein (NX_O75439)
Protein (NX_O75439)
Protein
Gene SymbolPMPCB to neXtProt (NX_O75439)
DescriptionMitochondrial-processing peptidase subunit beta
Chromosome7
Location7q22.1 (102937869 ~ 102969958) to Ensembl
Sequene Features : Isoforms 1, Variants 60, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.cellular protein metabolic process
.protein targeting to mitochondrion
.metal ion binding
.metalloendopeptidase activity
.mitochondrial matrix
.mitochondrial inner membrane
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 60 4
2014-09-19protein level
1 54 4
2014-05-27protein level
1 54 4
2014-02-25protein level
1 52 4
2013-12-09protein level
1 36 4
2013-11-01protein level
1 35 0
2013-09-12protein level
1 35 0
2013-08-17protein level
1 35 0
2013-07-15protein level
1 31 0
2013-06-11protein level
1 31 0
2013-02-12protein level
1 20 0
2012-12-20protein level
1 17 0
2012-10-30protein level
1 24 0
2012-10-07protein level
1 24 0
2012-08-24protein level
1 24 0
2012-07-28protein level
1 24 0
2012-06-08protein level
1 25 0
2012-05-07protein level
1 19 0
2012-04-10protein level
1 19 0
2012-01-13protein level
1 9 0
2011-12-20protein level
1 9 0
2011-11-11protein level
1 9 0
2011-08-23protein level
1 9 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_O75439-1
24 0 0 54331.3399
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adipose tissue77
adrenal gland425
ascites476
blood98
bone139
bone marrow102
brain157
cervix82
connective tissue87
embryonic tissue178
esophagus148
eye110
heart156
intestine163
kidney161
larynx127
liver136
lung125
lymph45
lymph node100
mammary gland85
muscle103
nerve64
ovary167
pancreas79
parathyroid145
pharynx270
pituitary gland302
placenta127
prostate142
salivary gland394
skin80
spleen37
stomach240
testis156
thymus200
thyroid128
tonsil293
trachea57
umbilical cord72
uterus168
vascular77
Health State
TissuesTPM*
normal129
adrenal tumor632
breast (mammary gland) tumor118
cervical tumor115
chondrosarcoma120
colorectal tumor204
esophageal tumor173
gastrointestinal tumor261
germ cell tumor140
glioma121
head and neck tumor156
kidney tumor116
leukemia63
liver tumor166
lung tumor145
lymphoma207
non-neoplasia113
ovarian tumor157
pancreatic tumor95
primitive neuroectodermal tumor of the CNS204
prostate cancer115
retinoblastoma279
skin tumor103
soft tissue/muscle tissue tumor87
uterine tumor144
Developmental Stage
TissuesTPM*
adult109
embryoid body128
blastocyst146
neonate64
fetus111
infant595
juvenile269
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue38.5
adrenal gland72.5
appendix45.8
bone marrow55.4
cerebral cortex36.5
colon54
duodenum54.8
esophagus44.8
gallbladder47.8
heart muscle64.5
kidney72
liver46.8
lung33.7
lymph node60.7
ovary59.8
pancreas23.9
placenta39.7
prostate51.2
salivary gland39.3
skin43.3
small intestine51
spleen38
stomach51.4
testis54.6
thyroid gland58.6
urinary bladder52.3
Tissues
TissuesExpression level
adrenal glandHigh
appendixMedium
bone marrowLow
breastMedium
bronchusMedium
cerebral cortexHigh
cervix, uterineLow
colonMedium
duodenumHigh
endometrium 1Low
endometrium 2Medium
epididymisMedium
esophagusMedium
fallopian tubeMedium
gallbladderMedium
heart muscleHigh
hippocampusMedium
kidneyMedium
lateral ventricleLow
liverMedium
lungMedium
lymph nodeMedium
nasopharynxMedium
oral mucosaMedium
pancreasHigh
parathyroid glandMedium
placentaLow
prostateMedium
rectumHigh
salivary glandLow
seminal vesicleMedium
skeletal muscleLow
skin 1High
skin 2Medium
small intestineHigh
spleenLow
stomach 1High
stomach 2Medium
testisHigh
thyroid glandMedium
tonsilHigh
urinary bladderMedium
vaginaMedium
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Expression level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*603131, gene) Peptidase, mitochondrial processing, beta; PMPCBOMIM


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