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> Protein (NX_O75462)
Protein (NX_O75462)
Protein
Gene SymbolCRLF1 to neXtProt (NX_O75462)
DescriptionCytokine receptor-like factor 1
Chromosome19
Location19p13.11 (18683030 ~ 18718551) to Ensembl
Sequene Features : Isoforms 1, Variants 59, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.negative regulation of motor neuron apoptotic process
.negative regulation of neuron apoptotic process
.positive regulation of tyrosine phosphorylation of Stat3 protein
  + 2 more...
.protein heterodimerization activity
.cytokine binding
.receptor activity
.CRLF-CLCF1 complex
.extracellular space
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 59 9
2014-09-19protein level
1 46 9
2014-05-27protein level
1 46 9
2014-02-25protein level
1 35 9
2013-12-09protein level
1 27 9
2013-11-01protein level
1 27 9
2013-09-12protein level
1 27 9
2013-08-17protein level
1 27 9
2013-07-15protein level
1 15 9
2013-06-11protein level
1 15 9
2013-02-12protein level
1 9 9
2012-12-20protein level
1 9 9
2012-10-30protein level
1 10 9
2012-10-07protein level
1 10 9
2012-08-24protein level
1 10 9
2012-07-28protein level
1 10 9
2012-06-08protein level
1 11 9
2012-05-07protein level
1 11 9
2012-04-10protein level
1 11 9
2012-01-13protein level
1 7 9
2011-12-20protein level
1 7 9
2011-11-11protein level
1 7 9
2011-08-23protein level
1 7 9
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_O75462-1
21 0 0 46272.4684
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
brain8
connective tissue60
embryonic tissue9
eye14
heart33
liver121
lung32
lymph45
mammary gland6
mouth105
ovary19
pancreas18
placenta3
skin33
thymus12
uterus25
Health State
TissuesTPM*
normal15
breast (mammary gland) tumor10
chondrosarcoma48
glioma27
liver tumor260
lymphoma27
non-neoplasia20
ovarian tumor26
primitive neuroectodermal tumor of the CNS7
skin tumor15
soft tissue/muscle tissue tumor7
Developmental Stage
TissuesTPM*
adult13
embryoid body28
fetus30
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue12
adrenal gland8.6
appendix4.9
bone marrow4.6
cerebral cortex12.7
colon3.5
duodenum2.2
esophagus6.1
gallbladder4.6
heart muscle10.4
kidney3.2
liver1
lung5.5
lymph node4.4
ovary2.6
pancreas3
placenta16.3
prostate2.2
salivary gland3.1
skin12.3
small intestine1.7
spleen2.2
stomach2
testis3.1
thyroid gland2
urinary bladder4.2
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(#272430, phenotype) Cold-induced sweating syndrome 1; CISS1OMIM
2(*604237, gene) Cytokine receptor-like factor 1; CRLF1OMIM


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