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> Protein (NX_O75477)
Protein (NX_O75477)
Protein
Gene SymbolERLIN1 to neXtProt (NX_O75477)
DescriptionErlin-1
Chromosome10
Location10q24.31 (101909851 ~ 101948091) to Ensembl
Sequene Features : Isoforms 1, Variants 3, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.ER-associated ubiquitin-dependent protein catabolic process .N/A .protein complex
.integral component of membrane
.endoplasmic reticulum membrane
.endoplasmic reticulum
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 3 4
2014-09-19protein level
1 14 4
2014-05-27protein level
1 14 4
2014-02-25protein level
1 14 4
2013-12-09protein level
1 13 4
2013-11-01protein level
1 13 3
2013-09-12protein level
1 13 3
2013-08-17protein level
1 13 3
2013-07-15protein level
1 6 3
2013-06-11protein level
1 6 3
2013-02-12protein level
1 2 3
2012-12-20protein level
1 2 3
2012-10-30protein level
1 1 3
2012-10-07protein level
1 1 3
2012-08-24protein level
1 1 3
2012-07-28protein level
1 1 3
2012-06-08protein level
1 2 3
2012-05-07protein level
1 2 3
2012-04-10protein level
1 2 3
2012-01-13protein level
1 4 3
2011-12-20protein level
1 4 3
2011-11-11protein level
1 4 2
2011-08-23protein level
1 4 2
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_O75477-1
13 0 3 38901.2371
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-359299,EBI-10265825 TMEM199  
  .N/A .N/A .integral component of membrane
2 EBI-359299,EBI-3925742 AGR3  
  .N/A .dystroglycan binding .extracellular region
3 EBI-359299,EBI-8652744 SEC22A  
  .vesicle fusion with Golgi apparatus
.protein transport
.ER to Golgi vesicle-mediated transport
.SNAP receptor activity
.transporter activity
.SNARE binding
.SNARE complex
.integral component of membrane
.endoplasmic reticulum membrane
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adipose tissue233
ascites125
bladder100
blood24
bone111
bone marrow82
brain21
cervix61
connective tissue33
embryonic tissue70
esophagus99
eye52
heart100
intestine77
kidney47
larynx42
liver63
lung29
lymph node33
mammary gland26
mouth75
muscle37
nerve64
ovary29
pancreas60
parathyroid48
pharynx24
pituitary gland60
placenta67
prostate5
skin28
spleen18
testis98
thymus75
thyroid21
trachea57
uterus47
vascular58
Health State
TissuesTPM*
normal45
bladder carcinoma113
breast (mammary gland) tumor32
cervical tumor86
chondrosarcoma120
colorectal tumor35
esophageal tumor115
gastrointestinal tumor50
germ cell tumor37
glioma74
head and neck tumor37
kidney tumor58
leukemia63
liver tumor93
lung tumor19
non-neoplasia20
ovarian tumor26
pancreatic tumor47
primitive neuroectodermal tumor of the CNS31
prostate cancer9
retinoblastoma86
skin tumor15
soft tissue/muscle tissue tumor7
uterine tumor55
Developmental Stage
TissuesTPM*
adult53
embryoid body42
blastocyst113
neonate32
fetus53
juvenile35
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue22.7
adrenal gland13.6
appendix20.1
bone marrow34.2
cerebral cortex8.3
colon35.3
duodenum31.9
esophagus29.8
gallbladder16.1
heart muscle8.2
kidney21.4
liver49.5
lung15.8
lymph node12.8
ovary27.1
pancreas7.9
placenta36.7
prostate15.6
salivary gland9.6
skin15.9
small intestine24.8
spleen13.9
stomach30.9
testis26.4
thyroid gland25.9
urinary bladder26.4
Tissues
TissuesExpression level
adrenal glandMedium
appendixHigh
bone marrowHigh
breastMedium
bronchusHigh
cerebellumLow
cerebral cortexHigh
cervix, uterineMedium
colonHigh
duodenumHigh
endometrium 1High
endometrium 2High
epididymisMedium
esophagusMedium
fallopian tubeMedium
gallbladderMedium
hippocampusMedium
kidneyMedium
lateral ventricleHigh
liverHigh
lungMedium
lymph nodeLow
nasopharynxHigh
oral mucosaMedium
ovaryMedium
pancreasLow
parathyroid glandLow
placentaHigh
prostateHigh
rectumHigh
salivary glandLow
seminal vesicleMedium
skin 1Medium
skin 2Medium
small intestineHigh
soft tissue 1Low
soft tissue 2Medium
spleenMedium
stomach 1High
stomach 2High
testisHigh
thyroid glandMedium
tonsilMedium
urinary bladderHigh
vaginaMedium
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Expression level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*611604, gene) Endoplasmic reticulum lipid raft-associated protein 1; ERLIN1OMIM


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