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> Protein (NX_O75575)
Protein (NX_O75575)
Protein
Gene SymbolCRCP to neXtProt (NX_O75575)
DescriptionDNA-directed RNA polymerase III subunit RPC9
Chromosome7
Location7q11.21 (65579591 ~ 65619555) to Ensembl
Sequene Features : Isoforms 4, Variants 20, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.defense response to virus
.innate immune response
.positive regulation of type I interferon production
  + 6 more...
.DNA-directed RNA polymerase activity
.calcitonin gene-related peptide receptor activity
.nucleotide binding
.DNA polymerase III complex
.plasma membrane
.cytosol
  + 3 more...
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
4 20 1
2014-09-19protein level
4 14 1
2014-05-27protein level
4 14 1
2014-02-25protein level
4 14 1
2013-12-09protein level
4 9 1
2013-11-01protein level
4 9 1
2013-09-12protein level
4 9 1
2013-08-17protein level
4 9 1
2013-07-15protein level
4 6 1
2013-06-11protein level
4 6 1
2013-02-12protein level
3 2 4
2012-12-20protein level
3 2 4
2012-10-30protein level
3 3 4
2012-10-07protein level
3 3 2
2012-08-24protein level
3 3 2
2012-07-28protein level
3 3 2
2012-06-08protein level
3 3 2
2012-05-07protein level
3 3 2
2012-04-10protein level
2 3 2
2012-01-13protein level
2 0 2
2011-12-20protein level
2 0 2
2011-11-11protein level
2 0 1
2011-08-23protein level
2 0 1
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_O75575-1
2 4 0 16860.5899
NX_O75575-2
0 5 0 13045.6408
NX_O75575-3
2 5 0 15602.7964
NX_O75575-4
0 3 0 8005.9537
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-2654687,EBI-745786 ZMIZ2  
  .positive regulation of transcription from RNA polymerase II promoter
.transcription, DNA-templated
.ligand-dependent nuclear receptor transcription coactivator activity
.zinc ion binding
.nuclear replication fork
.mitochondrion
.nucleoplasm
.nucleus
2 EBI-2654687,EBI-722877 TCF12  
  .positive regulation of transcription from RNA polymerase II promoter
.positive regulation of neuron differentiation
.muscle organ development
  + 2 more...
.E-box binding
.protein heterodimerization activity
.SMAD binding
  + 7 more...
.RNA polymerase II transcription factor complex
.cytoplasm
.nucleus
.nuclear chromatin
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adrenal gland91
bladder100
blood8
bone27
brain26
cervix61
connective tissue6
embryonic tissue18
esophagus198
eye19
heart22
intestine21
kidney28
liver38
lung11
lymph22
mammary gland19
mouth30
muscle28
ovary49
pharynx98
pituitary gland60
placenta10
prostate42
skin42
spleen74
stomach20
testis11
thymus25
thyroid236
trachea38
umbilical cord72
uterus34
vascular19
Health State
TissuesTPM*
normal19
adrenal tumor158
bladder carcinoma170
breast (mammary gland) tumor32
cervical tumor57
colorectal tumor26
esophageal tumor231
gastrointestinal tumor25
germ cell tumor34
glioma18
head and neck tumor82
kidney tumor43
liver tumor31
lung tumor29
lymphoma13
non-neoplasia20
ovarian tumor39
primitive neuroectodermal tumor of the CNS47
prostate cancer67
retinoblastoma64
skin tumor31
soft tissue/muscle tissue tumor15
uterine tumor11
Developmental Stage
TissuesTPM*
adult23
blastocyst16
neonate32
fetus17
juvenile53
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue15.7
adrenal gland17.3
appendix15.4
bone marrow24
cerebral cortex17.8
colon21.7
duodenum14.6
esophagus19
gallbladder15.7
heart muscle14.2
kidney17.4
liver13
lung15.7
lymph node17
ovary18.1
pancreas11.4
placenta14.4
prostate17.1
salivary gland13
skin14.2
small intestine14.7
spleen18.7
stomach19.8
testis12
thyroid gland23.1
urinary bladder19
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*606121, gene) Calcitonin gene-related peptide receptor component proteinOMIM


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