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> Protein (NX_O75821)
Protein (NX_O75821)
Protein
Gene SymbolEIF3G to neXtProt (NX_O75821)
DescriptionEukaryotic translation initiation factor 3 subunit G
Chromosome19
Location19p13.2 (10225693 ~ 10230596) to Ensembl
Sequene Features : Isoforms 1, Variants 32, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.cellular protein metabolic process
.gene expression
.regulation of translational initiation
  + 3 more...
.poly(A) RNA binding
.translation initiation factor activity
.nucleotide binding
.perinuclear region of cytoplasm
.eukaryotic 48S preinitiation complex
.eukaryotic 43S preinitiation complex
  + 3 more...
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 32 5
2014-09-19protein level
1 18 5
2014-05-27protein level
1 18 5
2014-02-25protein level
1 18 5
2013-12-09protein level
1 14 5
2013-11-01protein level
1 14 3
2013-09-12protein level
1 14 3
2013-08-17protein level
1 14 3
2013-07-15protein level
1 8 3
2013-06-11protein level
1 8 3
2013-02-12protein level
1 4 3
2012-12-20protein level
1 5 3
2012-10-30protein level
1 4 3
2012-10-07protein level
1 4 3
2012-08-24protein level
1 4 3
2012-07-28protein level
1 4 3
2012-06-08protein level
1 5 3
2012-05-07protein level
1 5 3
2012-04-10protein level
1 5 3
2012-01-13protein level
1 3 3
2011-12-20protein level
1 3 3
2011-11-11protein level
1 3 3
2011-08-23protein level
1 3 3
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_O75821-1
15 0 0 35588.8188
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-366632,EBI-356440 AIFM1  
  .regulation of apoptotic DNA fragmentation
.intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
.neuron apoptotic process
  + 9 more...
.FAD binding
.oxidoreductase activity, acting on NAD(P)H
.NAD(P)H oxidase activity
  + 2 more...
.perinuclear region of cytoplasm
.cytosol
.mitochondrial intermembrane space
  + 3 more...
2 EBI-366632,EBI-366696 EIF3B  
  .cellular protein metabolic process
.gene expression
.regulation of translational initiation
  + 3 more...
.protein complex scaffold
.translation initiation factor activity
.nucleotide binding
.eukaryotic translation initiation factor 3 complex, eIF3m
.extracellular exosome
.eukaryotic 48S preinitiation complex
  + 5 more...
3 EBI-366632,EBI-618309 GOLGA2  
  .negative regulation of protein binding
.mitotic cell cycle
.syntaxin binding
.protein kinase binding
.Golgi cisterna membrane
.ER to Golgi transport vesicle
.cis-Golgi network
  + 4 more...
4 EBI-366632,EBI-10175124 FAM9B  
  .spermatid development .N/A .nucleoplasm
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adipose tissue388
adrenal gland30
ascites175
bladder267
blood32
bone139
bone marrow143
brain99
cervix288
connective tissue73
embryonic tissue178
esophagus49
eye129
heart44
intestine125
kidney90
larynx42
liver87
lung200
lymph180
lymph node33
mammary gland72
mouth30
muscle235
nerve193
ovary206
pancreas145
pharynx49
pituitary gland60
placenta102
prostate105
salivary gland986
skin341
spleen131
stomach104
testis153
thymus50
tonsil58
uterus172
vascular58
Health State
TissuesTPM*
normal85
bladder carcinoma113
breast (mammary gland) tumor118
cervical tumor289
chondrosarcoma205
colorectal tumor124
esophageal tumor57
gastrointestinal tumor160
germ cell tumor140
glioma242
head and neck tumor97
kidney tumor87
leukemia105
liver tumor124
lung tumor350
lymphoma166
non-neoplasia51
ovarian tumor196
pancreatic tumor152
primitive neuroectodermal tumor of the CNS133
prostate cancer134
retinoblastoma193
skin tumor534
soft tissue/muscle tissue tumor143
uterine tumor188
Developmental Stage
TissuesTPM*
adult117
embryoid body271
blastocyst195
fetus53
infant42
juvenile53
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue89
adrenal gland84
appendix91.7
bone marrow101.7
cerebral cortex55.1
colon79
duodenum77.4
esophagus69.7
gallbladder82.8
heart muscle81.4
kidney77.9
liver52.5
lung78.7
lymph node126.8
ovary168.3
pancreas83.5
placenta91.4
prostate91.9
salivary gland131.5
skin97.8
small intestine76
spleen117.9
stomach88.7
testis110
thyroid gland88
urinary bladder90.9
Tissues
TissuesExpression level
adrenal glandMedium
appendixHigh
bone marrowHigh
breastHigh
bronchusHigh
cerebellumHigh
cerebral cortexHigh
cervix, uterineHigh
colonHigh
duodenumMedium
endometrium 1Medium
endometrium 2High
epididymisHigh
esophagusHigh
fallopian tubeHigh
gallbladderHigh
hippocampusLow
kidneyMedium
lateral ventricleLow
liverLow
lungMedium
lymph nodeHigh
nasopharynxHigh
oral mucosaMedium
ovaryLow
pancreasHigh
parathyroid glandMedium
placentaHigh
prostateHigh
rectumHigh
salivary glandHigh
seminal vesicleHigh
skeletal muscleLow
skin 1Medium
skin 2High
small intestineHigh
smooth muscleLow
soft tissue 1Low
spleenHigh
stomach 1High
stomach 2High
testisMedium
thyroid glandMedium
tonsilHigh
urinary bladderHigh
vaginaHigh
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Expression level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*603913, gene) Eukaryotic translation initiation factor 3, subunit g; EIF3GOMIM


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