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> Protein (NX_O75864)
Protein (NX_O75864)
Protein
Gene SymbolPPP1R37 to neXtProt (NX_O75864)
DescriptionProtein phosphatase 1 regulatory subunit 37
Chromosome19
Location19q13.32 (45594654 ~ 45651335) to Ensembl
Sequene Features : Isoforms 2, Variants 8, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.negative regulation of phosphatase activity .phosphatase binding
.protein phosphatase inhibitor activity
.N/A
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
2 8 3
2014-09-19protein level
2 6 3
2014-05-27protein level
2 6 3
2014-02-25protein level
2 6 3
2013-12-09protein level
2 6 3
2013-11-01protein level
2 6 3
2013-09-12protein level
2 6 3
2013-08-17protein level
2 6 3
2013-07-15protein level
2 6 2
2013-06-11protein level
2 6 2
2013-02-12protein level
2 6 2
2012-12-20protein level
2 6 2
2012-10-30protein level
2 6 2
2012-10-07protein level
2 6 1
2012-08-24protein level
2 6 1
2012-07-28protein level
2 6 1
2012-06-08protein level
2 6 1
2012-05-07protein level
2 6 1
2012-04-10protein level
2 6 1
2012-01-13protein level
2 3 1
2011-12-20protein level
2 3 1
2011-11-11protein level
2 3 1
2011-08-23protein level
2 3 1
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_O75864-1
21 6 0 74720.6404
NX_O75864-2
5 6 0 26272.7677
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-5235692,EBI-357253 PPP1CA  
  .positive regulation of extrinsic apoptotic signaling pathway in absence of ligand
.cell division
.branching morphogenesis of an epithelial tube
  + 15 more...
.metal ion binding
.ribonucleoprotein complex binding
.phosphatase activity
.protein serine/threonine phosphatase activity
.PTW/PP1 phosphatase complex
.MLL5-L complex
.extracellular exosome
  + 10 more...
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
bladder33
brain9
cervix20
embryonic tissue23
eye47
heart22
intestine12
kidney28
larynx85
liver4
lung14
lymph node44
ovary9
pancreas46
parathyroid48
pituitary gland121
placenta10
skin52
spleen37
stomach20
testis9
thymus12
thyroid42
uterus21
Health State
TissuesTPM*
normal19
colorectal tumor8
gastrointestinal tumor8
germ cell tumor11
glioma65
head and neck tumor14
kidney tumor58
leukemia21
liver tumor10
lung tumor9
pancreatic tumor19
skin tumor55
soft tissue/muscle tissue tumor15
uterine tumor33
Developmental Stage
TissuesTPM*
adult14
embryoid body14
blastocyst48
neonate64
fetus16
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue6.5
adrenal gland12.2
appendix5.7
bone marrow3.6
cerebral cortex12.2
colon8.6
duodenum8.7
esophagus5.8
gallbladder5.4
heart muscle4.6
kidney11.1
liver3.9
lung6.9
lymph node5
ovary4.7
pancreas4.4
placenta5.5
prostate11
salivary gland10.6
skin9.5
small intestine9.2
spleen8.9
stomach15.2
testis8.8
thyroid gland6.7
urinary bladder6.1
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected


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