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> Protein (NX_O75865)
Protein (NX_O75865)
Protein
Gene SymbolTRAPPC6A to neXtProt (NX_O75865)
DescriptionTrafficking protein particle complex subunit 6A
Chromosome19
Location19q13.32 (45666186 ~ 45681495) to Ensembl
Sequene Features : Isoforms 4, Variants 61, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.vesicle-mediated transport .N/A .Golgi apparatus
.endoplasmic reticulum
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
4 61 0
2014-09-19protein level
4 48 0
2014-05-27protein level
4 43 0
2014-02-25protein level
4 43 0
2013-12-09protein level
4 24 0
2013-11-01protein level
4 23 0
2013-09-12protein level
4 23 0
2013-08-17protein level
4 23 0
2013-07-15protein level
2 11 0
2013-06-11protein level
2 11 0
2013-02-12protein level
2 6 0
2012-12-20protein level
2 7 0
2012-10-30protein level
2 9 0
2012-10-07protein level
2 9 0
2012-08-24protein level
2 8 0
2012-07-28protein level
2 8 0
2012-06-08protein level
2 9 0
2012-05-07protein level
2 9 0
2012-04-10protein level
2 9 0
2012-01-13protein level
2 4 0
2011-12-20protein level
2 4 0
2011-11-11protein level
2 4 0
2011-08-23protein level
2 4 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_O75865-1
1 6 0 17593.0042
NX_O75865-2
0 8 0 18919.6894
NX_O75865-3
1 1 0 11640.7846
NX_O75865-4
1 3 0 12967.4698
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-743573,EBI-743566 TRAPPC3  
  .vesicle-mediated transport .N/A .Golgi apparatus
.endoplasmic reticulum
2 EBI-743573,EBI-10182121 ZMIZ2  
  .positive regulation of transcription from RNA polymerase II promoter
.transcription, DNA-templated
.ligand-dependent nuclear receptor transcription coactivator activity
.zinc ion binding
.nuclear replication fork
.mitochondrion
.nucleoplasm
.nucleus
3 EBI-743573,EBI-747844 RAB3IP  
  .positive regulation of GTPase activity
.cilium assembly
.protein localization to organelle
  + 3 more...
.Rab guanyl-nucleotide exchange factor activity .ciliary basal body
.lamellipodium
.cytoskeleton
  + 3 more...
4 EBI-743573,EBI-747204 IKZF3  
  .regulation of lymphocyte differentiation
.regulation of B cell differentiation
.regulation of apoptotic process
  + 5 more...
.protein heterodimerization activity
.metal ion binding
.sequence-specific DNA binding
  + 2 more...
.plasma membrane
.cytoplasm
.nucleus
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adipose tissue77
adrenal gland30
ascites25
blood32
bone69
brain6
connective tissue20
embryonic tissue28
eye52
heart33
intestine30
kidney14
lung32
lymph45
lymph node100
mammary gland26
ovary59
pancreas18
pharynx24
placenta10
prostate26
skin23
stomach10
testis18
vascular19
Health State
TissuesTPM*
normal13
adrenal tumor79
bladder carcinoma56
breast (mammary gland) tumor32
chondrosarcoma72
colorectal tumor44
gastrointestinal tumor50
germ cell tumor18
glioma18
leukemia63
lung tumor29
lymphoma27
ovarian tumor52
pancreatic tumor38
prostate cancer19
retinoblastoma43
skin tumor39
soft tissue/muscle tissue tumor7
Developmental Stage
TissuesTPM*
adult17
embryoid body14
blastocyst48
fetus12
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue13.3
adrenal gland12.9
appendix11.3
bone marrow28.5
cerebral cortex9.7
colon21.9
duodenum16.2
esophagus14.3
gallbladder16.8
heart muscle11.6
kidney38.8
liver17.1
lung16.1
lymph node28.9
ovary12.2
pancreas13.8
placenta11.6
prostate25.6
salivary gland22.5
skin26.8
small intestine15.8
spleen28.1
stomach24.4
testis15.5
thyroid gland30.8
urinary bladder15.6
Tissues
TissuesExpression level
adrenal glandHigh
appendixMedium
bone marrowLow
breastMedium
bronchusMedium
cerebellumMedium
cerebral cortexMedium
cervix, uterineMedium
colonMedium
duodenumHigh
endometrium 1Medium
endometrium 2Medium
epididymisLow
esophagusMedium
fallopian tubeLow
gallbladderMedium
heart muscleLow
hippocampusLow
kidneyMedium
liverMedium
lungMedium
lymph nodeMedium
nasopharynxMedium
pancreasHigh
placentaMedium
prostateMedium
rectumMedium
salivary glandHigh
seminal vesicleMedium
skeletal muscleMedium
skin 1Medium
skin 2Medium
small intestineHigh
soft tissue 1Medium
soft tissue 2Low
stomach 1Medium
stomach 2High
testisMedium
thyroid glandMedium
tonsilMedium
urinary bladderLow
vaginaMedium
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Expression level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*610396, gene) Trafficking protein particle complex, subunit 6a; TRAPPC6AOMIM


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