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> Protein (NX_O75971)
Protein (NX_O75971)
Protein
Gene SymbolSNAPC5 to neXtProt (NX_O75971)
DescriptionsnRNA-activating protein complex subunit 5
Chromosome15
Location15q22.31 (66782473 ~ 66790151) to Ensembl
Sequene Features : Isoforms 2, Variants 9, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.gene expression
.transcription initiation from RNA polymerase III promoter
.transcription from RNA polymerase III promoter
.transcription from RNA polymerase II promoter
.sequence-specific DNA binding transcription factor activity .nucleolus
.nucleoplasm
.nucleus
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
2 9 2
2014-09-19protein level
2 8 2
2014-05-27protein level
2 8 2
2014-02-25protein level
2 9 2
2013-12-09protein level
2 7 2
2013-11-01protein level
2 7 2
2013-09-12protein level
2 7 2
2013-08-17protein level
2 7 2
2013-07-15protein level
2 5 2
2013-06-11protein level
2 5 2
2013-02-12protein level
2 5 4
2012-12-20protein level
2 5 4
2012-10-30protein level
2 5 4
2012-10-07protein level
2 5 2
2012-08-24protein level
2 3 2
2012-07-28protein level
2 3 2
2012-06-08protein level
2 5 2
2012-05-07protein level
2 5 2
2012-04-10protein level
2 5 2
2012-01-13protein level
2 4 2
2011-12-20protein level
2 4 2
2011-11-11protein level
2 4 2
2011-08-23protein level
2 4 2
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_O75971-1
2 2 0 11321.4939
NX_O75971-2
1 2 0 7971.9366
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-749483,EBI-741415 SSSCA1  
  .cell division
.mitotic nuclear division
.N/A .N/A
2 EBI-749483,EBI-10190763 NOL4  
  .N/A .RNA binding .nucleolus
.nucleus
3 EBI-749483,EBI-10173632 DDIT3  
  .negative regulation of determination of dorsal identity
.positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress
.negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding
  + 32 more...
.protein heterodimerization activity
.transcription regulatory region DNA binding
.leucine zipper domain binding
  + 8 more...
.CHOP-ATF3 complex
.CHOP-ATF4 complex
.CHOP-C/EBP complex
  + 5 more...
4 EBI-749483,EBI-347978 NUP62  
  .regulation of cellular response to heat
.transmembrane transport
.mRNA transport
  + 34 more...
.thyroid hormone receptor binding
.ubiquitin binding
.SH2 domain binding
  + 3 more...
.Flemming body
.pore complex
.intracellular membrane-bounded organelle
  + 7 more...
5 EBI-749483,EBI-372942 NMI  
  .regulation of nucleic acid-templated transcription
.JAK-STAT cascade
.inflammatory response
.transcription from RNA polymerase II promoter
.transcription cofactor activity .cytoplasm
.nucleoplasm
6 EBI-749483,EBI-3891843 AMOT  
  .positive regulation of stress fiber assembly
.positive regulation of cell size
.positive regulation of blood vessel endothelial cell migration
  + 16 more...
.angiostatin binding
.receptor activity
.endocytic vesicle
.lamellipodium
.integral component of membrane
  + 8 more...
7 EBI-749483,EBI-726826 NUDT10  
  .small molecule metabolic process
.inositol phosphate metabolic process
.inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity
.inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity
.inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity
  + 6 more...
.cytosol
8 EBI-749483,EBI-928842 NDEL1  
  .neuron projection extension
.neurofilament cytoskeleton organization
.centrosome localization
  + 20 more...
.oligopeptidase activity
.microtubule binding
.neurofilament cytoskeleton
.axon hillock
.cell leading edge
  + 10 more...
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adrenal gland60
ascites50
bladder66
blood57
bone41
bone marrow82
brain36
cervix61
connective tissue6
embryonic tissue32
eye33
heart22
intestine30
kidney14
larynx42
liver19
lung41
lymph112
lymph node33
mouth60
muscle9
pancreas18
parathyroid291
pharynx98
placenta21
prostate21
skin37
spleen56
testis43
thymus25
thyroid85
umbilical cord217
uterus21
Health State
TissuesTPM*
normal40
adrenal tumor79
bladder carcinoma56
cervical tumor28
chondrosarcoma36
colorectal tumor17
gastrointestinal tumor16
germ cell tumor15
glioma18
head and neck tumor52
kidney tumor29
leukemia31
liver tumor20
lymphoma69
non-neoplasia41
pancreatic tumor19
primitive neuroectodermal tumor of the CNS7
prostate cancer19
retinoblastoma43
skin tumor23
soft tissue/muscle tissue tumor7
Developmental Stage
TissuesTPM*
adult34
embryoid body42
blastocyst32
neonate96
fetus41
infant42
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue21.3
adrenal gland26.2
appendix21.6
bone marrow8.2
cerebral cortex28.9
colon21.9
duodenum14.3
esophagus18.6
gallbladder18.7
heart muscle35.4
kidney29.9
liver23.9
lung21.1
lymph node26.4
ovary18.7
pancreas9.9
placenta16.3
prostate25.7
salivary gland15.7
skin10.1
small intestine15.7
spleen21.6
stomach17.4
testis28.7
thyroid gland28.6
urinary bladder25.2
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*605979, gene) Small nuclear rna-activating protein complex, polypeptide 5; SNAPC5OMIM


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