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> Protein (NX_O95050)
Protein (NX_O95050)
Protein
Gene SymbolINMT to neXtProt (NX_O95050)
DescriptionIndolethylamine N-methyltransferase
Chromosome7
Location7p14.3 (30737601 ~ 30797218) to Ensembl
Sequene Features : Isoforms 2, Variants 61, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.methylation
.response to toxic substance
.amine metabolic process
.amine N-methyltransferase activity
.thioether S-methyltransferase activity
.cytosol
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
2 61 2
2014-09-19protein level
2 50 2
2014-05-27protein level
2 50 2
2014-02-25protein level
2 50 0
2013-12-09protein level
2 42 0
2013-11-01protein level
2 42 0
2013-09-12protein level
2 42 0
2013-08-17protein level
2 42 0
2013-07-15protein level
2 34 0
2013-06-11protein level
2 34 0
2013-02-12protein level
1 19 0
2012-12-20protein level
1 19 0
2012-10-30protein level
1 21 0
2012-10-07protein level
1 21 0
2012-08-24protein level
1 21 0
2012-07-28protein level
1 21 0
2012-06-08protein level
1 22 0
2012-05-07protein level
1 20 0
2012-04-10protein level
1 20 0
2012-01-13protein level
1 12 0
2011-12-20protein level
1 12 0
2011-11-11protein level
1 12 0
2011-08-23protein level
1 12 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_O95050-1
1 10 0 28872.2998
NX_O95050-2
1 10 0 28815.2785
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-10191038,EBI-740929 KLHL12  
  .negative regulation of canonical Wnt signaling pathway
.COPII vesicle coating
.Wnt signaling pathway
  + 2 more...
.N/A .Cul3-RING ubiquitin ligase complex
.ER to Golgi transport vesicle
.cytosol
.Golgi membrane
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adipose tissue388
adrenal gland30
brain5
cervix20
connective tissue46
embryonic tissue4
heart44
intestine8
kidney33
lung53
prostate58
skin9
spleen18
testis39
thyroid85
uterus4
Health State
TissuesTPM*
normal17
chondrosarcoma84
germ cell tumor15
head and neck tumor22
non-neoplasia20
skin tumor7
Developmental Stage
TissuesTPM*
adult13
fetus19
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue21.8
adrenal gland30.9
appendix3.2
colon6.2
duodenum2.9
esophagus15.7
gallbladder9.9
heart muscle37.1
kidney5.5
liver9.3
lung108.8
lymph node8.1
ovary3.7
pancreas2.9
placenta25.6
prostate27.5
salivary gland7.9
skin2.5
small intestine4.2
spleen7.2
stomach2.2
testis17.8
thyroid gland12.5
urinary bladder12.2
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*604854, gene) Indolethylamine n-methyltransferase; INMTOMIM


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