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> Protein (NX_O95073)
Protein (NX_O95073)
Protein
Gene SymbolFSBP to neXtProt (NX_O95073)
DescriptionFibrinogen silencer-binding protein
Chromosome8
Location8q22.1 (95384188 ~ 95487337) to Ensembl
Sequene Features : Isoforms 2, Variants 5, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.regulation of transcription, DNA-templated
.transcription, DNA-templated
.identical protein binding .nucleus
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
2 5 2
2014-09-19protein level
2 3 2
2014-05-27protein level
2 3 3
2014-02-25protein level
2 3 3
2013-12-09protein level
2 2 3
2013-11-01protein level
2 2 2
2013-09-12protein level
2 2 2
2013-08-17protein level
2 2 2
2013-07-15protein level
2 2 2
2013-06-11protein level
2 2 2
2013-02-12protein level
2 2 2
2012-12-20protein level
2 3 2
2012-10-30protein level
2 3 2
2012-10-07protein level
2 3 1
2012-08-24protein level
2 3 1
2012-07-28protein level
2 5 1
2012-06-08protein level
2 5 1
2012-05-07protein level
2 5 1
2012-04-10transcript level
2 5 1
2012-01-13transcript level
2 2 1
2011-12-20transcript level
2 2 1
2011-11-11transcript level
2 2 0
2011-08-23protein level
2 2 0
2011-08-23protein level
2 2 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_O95073-1
6 10 0 34745.9721
NX_O95073-2
1 10 0 18614.5433
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-10696047,EBI-617403 PLCG2  
  .release of sequestered calcium ion into cytosol
.B cell receptor signaling pathway
.T cell receptor signaling pathway
  + 19 more...
.signal transducer activity
.phospholipase C activity
.phosphatidylinositol phospholipase C activity
.extracellular exosome
.plasma membrane
.cytosol
2 EBI-1059030,EBI-80140 SUMO1  
  .protein localization to nuclear pore
.regulation of interferon-gamma-mediated signaling pathway
.interferon-gamma-mediated signaling pathway
  + 13 more...
.poly(A) RNA binding
.ubiquitin protein ligase binding
.SUMO transferase activity
.transcription factor binding
.synapse
.nuclear membrane
.dendrite
  + 8 more...
3 EBI-1059030,EBI-1181405 PRKAA1  
  .negative regulation of glucose import in response to insulin stimulus
.regulation of energy homeostasis
.response to camptothecin
  + 42 more...
.[acetyl-CoA carboxylase] kinase activity
.tau-protein kinase activity
.[hydroxymethylglutaryl-CoA reductase (NADPH)] kinase activity
  + 7 more...
.AMP-activated protein kinase complex
.apical plasma membrane
.cytosol
  + 4 more...
4 EBI-1059030,EBI-1166928 ATPAF2  
  .proton-transporting ATP synthase complex assembly .N/A .nuclear speck
.mitochondrion
5 EBI-1059030,EBI-954696 TCEANC  
  .regulation of DNA-templated transcription, elongation
.regulation of transcription from RNA polymerase II promoter
.transcription, DNA-templated
.DNA binding .nucleus
6 EBI-1059030,EBI-744859 ANKRD36BP1  
  .N/A .N/A .N/A
7 EBI-1059030,EBI-744099 ENKD1  
  .N/A .N/A .microtubule cytoskeleton
.cytoplasmic microtubule
8 EBI-10696047,EBI-490630 SH2D2A  
  .vascular endothelial growth factor receptor signaling pathway
.cell differentiation
.positive regulation of signal transduction
  + 3 more...
.SH3/SH2 adaptor activity .cytosol
.cytoplasm
9 EBI-1059030,EBI-396137 CDC23  
  .protein K11-linked ubiquitination
.regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
.positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition
  + 11 more...
.ubiquitin-protein transferase activity .cytosol
.anaphase-promoting complex
.nucleoplasm
.intracellular
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
ascites75
bladder33
blood8
bone marrow41
brain12
cervix41
connective tissue20
ear124
embryonic tissue28
eye19
intestine17
kidney9
larynx42
liver19
lymph node44
mammary gland105
placenta10
prostate10
skin9
stomach52
testis4
thymus12
trachea19
uterus21
Health State
TissuesTPM*
normal9
breast (mammary gland) tumor10
colorectal tumor8
gastrointestinal tumor67
germ cell tumor15
glioma18
head and neck tumor7
kidney tumor14
leukemia21
liver tumor20
lymphoma13
non-neoplasia20
primitive neuroectodermal tumor of the CNS15
soft tissue/muscle tissue tumor23
uterine tumor33
Developmental Stage
TissuesTPM*
adult5
embryoid body14
blastocyst16
neonate32
fetus1
juvenile17
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue1.6
adrenal gland2.5
appendix2.4
bone marrow2
cerebral cortex1.7
colon2.4
duodenum2.5
esophagus2.6
gallbladder1.8
heart muscle1.4
kidney1.4
liver1.3
lung1.8
lymph node4.1
ovary3.1
placenta1.7
prostate3.8
skin4
small intestine2
spleen1.6
stomach2.6
testis5.1
thyroid gland1.9
urinary bladder3.2
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected


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