Home| Contact Us

HOME SEARCH STATISTICS
> Protein (NX_O95166)
Protein (NX_O95166)
Protein
Gene SymbolGABARAP to neXtProt (NX_O95166)
DescriptionGamma-aminobutyric acid receptor-associated protein
Chromosome17
Location17p13.1 (7143333 ~ 7146089) to Ensembl
Sequene Features : Isoforms 1, Variants 8, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.membrane fusion
.nucleophagy
.extrinsic apoptotic signaling pathway via death domain receptors
  + 5 more...
.GABA receptor binding
.beta-tubulin binding
.microtubule binding
.perinuclear region of cytoplasm
.cell body
.cytoplasmic vesicle
  + 13 more...
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 8 1
2014-09-19protein level
1 8 1
2014-05-27protein level
1 8 2
2014-02-25protein level
1 8 2
2013-12-09protein level
1 6 2
2013-11-01protein level
1 6 1
2013-09-12protein level
1 6 1
2013-08-17protein level
1 6 1
2013-07-15protein level
1 2 0
2013-06-11protein level
1 2 0
2013-02-12protein level
1 0 0
2012-12-20protein level
1 0 0
2012-10-30protein level
1 1 0
2012-10-07protein level
1 1 0
2012-08-24protein level
1 1 0
2012-07-28protein level
1 1 0
2012-06-08protein level
1 1 0
2012-05-07protein level
1 1 0
2012-04-10protein level
1 1 0
2012-01-13protein level
1 1 0
2011-12-20protein level
1 1 0
2011-11-11protein level
1 1 0
2011-08-23protein level
1 1 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_O95166-1
1 0 1 13909.2405
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-712001,EBI-356424 IPO5  
  .cellular response to amino acid stimulus
.positive regulation of protein import into nucleus
.negative regulation of GTPase activity
  + 3 more...
.poly(A) RNA binding
.protein transporter activity
.Ran GTPase binding
.GTPase inhibitor activity
.intracellular membrane-bounded organelle
.nuclear membrane
.membrane
  + 6 more...
2 EBI-712001,EBI-2946991 TECPR2  
  .autophagy .N/A .N/A
3 EBI-712001,EBI-307133 GBAS  
  .negative regulation of ATP citrate synthase activity
.ATP biosynthetic process
.oxidative phosphorylation
.N/A .membrane
.integral component of plasma membrane
.mitochondrion
4 EBI-712001,EBI-2947137 STBD1  
  .muscle contraction .starch binding .membrane
.integral component of plasma membrane
5 EBI-712001,EBI-987834 ATG7  
  .negative regulation of histone H4-K16 acetylation
.regulation of mitochondrion degradation
.cellular response to hyperoxia
  + 33 more...
.protein homodimerization activity
.Atg8 activating enzyme activity
.Atg12 activating enzyme activity
  + 2 more...
.axoneme
.cytosol
.cytoplasm
.pre-autophagosomal structure
6 EBI-712001,EBI-1049597 CALR  
  .positive regulation of dendritic cell chemotaxis
.positive regulation of substrate adhesion-dependent cell spreading
.cellular senescence
  + 42 more...
.chaperone binding
.unfolded protein binding
.androgen receptor binding
  + 14 more...
.endocytic vesicle lumen
.integral component of lumenal side of endoplasmic reticulum membrane
.extracellular exosome
  + 20 more...
7 EBI-712001,EBI-356720 HADHA  
  .glycerophospholipid biosynthetic process
.small molecule metabolic process
.cellular lipid metabolic process
  + 5 more...
.NAD binding
.long-chain-3-hydroxyacyl-CoA dehydrogenase activity
.long-chain-enoyl-CoA hydratase activity
  + 4 more...
.mitochondrial nucleoid
.mitochondrial fatty acid beta-oxidation multienzyme complex
.mitochondrial inner membrane
.mitochondrion
8 EBI-712001,EBI-726944 NEDD4  
  .negative regulation of sodium ion transmembrane transporter activity
.regulation of potassium ion transmembrane transporter activity
.protein K63-linked ubiquitination
  + 32 more...
.proline-rich region binding
.RNA polymerase binding
.ubiquitin protein ligase activity
  + 7 more...
.extracellular exosome
.perinuclear region of cytoplasm
.apicolateral plasma membrane
  + 8 more...
9 EBI-712001,EBI-367376 STK4  
  .positive regulation of extrinsic apoptotic signaling pathway via death domain receptors
.hepatocyte apoptotic process
.negative regulation of canonical Wnt signaling pathway
  + 25 more...
.protein dimerization activity
.protein serine/threonine kinase activator activity
.protein homodimerization activity
  + 6 more...
.cytosol
.cytoplasm
.nucleoplasm
.nucleus
10 EBI-712001,EBI-992580 STK3  
  .positive regulation of extrinsic apoptotic signaling pathway via death domain receptors
.hepatocyte apoptotic process
.negative regulation of canonical Wnt signaling pathway
  + 25 more...
.protein dimerization activity
.protein serine/threonine kinase activator activity
.ATP binding
  + 4 more...
.cytosol
.cytoplasm
.nucleus
11 EBI-712001,EBI-307104 SQSTM1  
  .activation of mitophagy in response to mitochondrial depolarization
.apoptotic signaling pathway
.protein heterooligomerization
  + 20 more...
.ubiquitin binding
.identical protein binding
.SH2 domain binding
  + 5 more...
.extracellular exosome
.cytoplasmic vesicle
.PML body
  + 11 more...
12 EBI-712001,EBI-742698 NBR1  
  .protein oligomerization
.negative regulation of osteoblast differentiation
.regulation of stress-activated MAPK cascade
  + 2 more...
.mitogen-activated protein kinase binding
.ubiquitin binding
.zinc ion binding
.extracellular exosome
.M band
.cytoplasmic vesicle
  + 6 more...
13 EBI-712001,EBI-2514077 ATG2A  
  .nucleophagy
.cellular response to nitrogen starvation
.mitochondrion degradation
.autophagic vacuole assembly
.N/A .pre-autophagosomal structure membrane
.extrinsic component of membrane
.lipid particle
.pre-autophagosomal structure
14 EBI-712001,EBI-2514778 KBTBD6  
  .N/A .N/A .N/A
15 EBI-712001,EBI-80799 NCOA7  
  .positive regulation of transcription from RNA polymerase II promoter
.transcription, DNA-templated
.nuclear hormone receptor binding
.ligand-dependent nuclear receptor transcription coactivator activity
.nucleus
.intracellular
16 EBI-712001,EBI-1048247 TBC1D15  
  .positive regulation of GTPase activity
.regulation of GTPase activity
.GTPase activator activity .extracellular exosome
.mitochondrion
.cytoplasm
17 EBI-712001,EBI-1044009 NEK9  
  .cell division
.mitotic nuclear envelope disassembly
.mitotic nuclear division
  + 2 more...
.metal ion binding
.protein kinase binding
.ATP binding
.protein serine/threonine kinase activity
.cytosol
.nucleus
18 EBI-712001,EBI-2946919 FNIP1  
  .regulation of pro-B cell differentiation
.positive regulation of GTPase activity
.negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
  + 9 more...
.guanyl-nucleotide exchange factor activity .cytoplasm
19 EBI-712001,EBI-473695 KBTBD7  
  .N/A .N/A .N/A
20 EBI-712001,EBI-367390 RASSF5  
  .regulation of protein localization to nucleus
.intracellular signal transduction
.positive regulation of protein ubiquitination
  + 2 more...
.metal ion binding .microtubule
.cytoplasm
.nucleus
21 EBI-712001,EBI-2946907 DYX1C1  
  .regulation of proteasomal protein catabolic process
.inner dynein arm assembly
.outer dynein arm assembly
  + 4 more...
.estrogen receptor binding .plasma membrane
.cytoplasm
.nucleus
22 EBI-712001,EBI-2947053 NSMAF  
  .positive regulation of apoptotic process
.intracellular signal transduction
.endosomal transport
  + 2 more...
.sphingomyelin phosphodiesterase activator activity
.phospholipid binding
.receptor signaling protein activity
.extrinsic component of membrane
.endomembrane system
.cytoplasm
23 EBI-712001,EBI-1111248 FNBP1  
  .endocytosis .identical protein binding
.lipid binding
.cytoplasmic membrane-bounded vesicle
.cell cortex
.coated pit
  + 3 more...
24 EBI-712001,EBI-2869338 FYCO1  
  .plus-end-directed vesicle transport along microtubule .metal ion binding .cytoplasmic vesicle
.integral component of membrane
.membrane
  + 3 more...
25 EBI-712001,EBI-747805 UBA5  
  .protein polyufmylation
.protein ufmylation
.response to endoplasmic reticulum stress
.regulation of intracellular estrogen receptor signaling pathway
.UFM1 activating enzyme activity
.metal ion binding
.ATP binding
.intracellular membrane-bounded organelle
.cytosol
.cytoplasm
.nucleus
26 EBI-712001,EBI-2515241 DDX47  
  .RNA secondary structure unwinding
.extrinsic apoptotic signaling pathway via death domain receptors
.RNA splicing
  + 2 more...
.poly(A) RNA binding
.ATP binding
.ATP-dependent RNA helicase activity
.membrane
.cytoplasm
.nucleolus
27 EBI-712001,EBI-1047414 ATG5  
  .negative regulation of histone H4-K16 acetylation
.regulation of reactive oxygen species metabolic process
.regulation of cilium assembly
  + 23 more...
.N/A .ER-mitochondrion membrane contact site
.Atg12-Atg5-Atg16 complex
.pre-autophagosomal structure membrane
  + 4 more...
28 EBI-712001,EBI-367363 RASSF1  
  .negative regulation of cell cycle arrest
.protein stabilization
.positive regulation of protein ubiquitination
  + 3 more...
.protein N-terminus binding
.identical protein binding
.zinc ion binding
.microtubule cytoskeleton
.plasma membrane
.microtubule
  + 4 more...
29 EBI-712001,EBI-988094 ATG3  
  .regulation of cilium assembly
.nucleophagy
.mitochondrial fragmentation involved in apoptotic process
  + 5 more...
.enzyme binding
.ubiquitin-like protein transferase activity
.Atg12 transferase activity
  + 2 more...
.cytosol
.cytoplasmic ubiquitin ligase complex
30 EBI-712001,EBI-2947180 TBC1D2B  
  .N/A .GTPase activator activity .N/A
31 EBI-712001,EBI-712014 ATG4B  
  .protein delipidation
.positive regulation of protein catabolic process
.nucleophagy
  + 9 more...
.cysteine-type peptidase activity
.cysteine-type endopeptidase activity
.endopeptidase activity
.cytosol
.cytoplasm
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adipose tissue466
adrenal gland364
ascites125
bladder267
blood229
bone55
bone marrow184
brain141
cervix41
connective tissue107
ear124
embryonic tissue131
eye186
heart256
intestine81
kidney170
larynx340
liver68
lung155
lymph90
lymph node111
mammary gland271
mouth30
muscle206
nerve64
ovary226
pancreas337
parathyroid48
pharynx171
pituitary gland302
placenta130
prostate427
salivary gland98
skin170
spleen56
stomach167
testis255
thymus37
thyroid1481
tonsil117
umbilical cord145
uterus172
vascular116
Health State
TissuesTPM*
normal151
adrenal tumor632
bladder carcinoma398
breast (mammary gland) tumor107
cervical tumor57
chondrosarcoma229
colorectal tumor71
gastrointestinal tumor160
germ cell tumor49
glioma158
head and neck tumor538
kidney tumor348
leukemia169
liver tumor62
lung tumor204
lymphoma110
non-neoplasia41
ovarian tumor196
pancreatic tumor552
primitive neuroectodermal tumor of the CNS47
prostate cancer500
retinoblastoma150
skin tumor79
soft tissue/muscle tissue tumor191
uterine tumor122
Developmental Stage
TissuesTPM*
adult241
embryoid body214
blastocyst48
neonate64
fetus114
infant85
juvenile53
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue332.2
adrenal gland493.2
appendix320
bone marrow299.5
cerebral cortex301.9
colon336.2
duodenum257.2
esophagus226.9
gallbladder319.2
heart muscle324.1
kidney351.1
liver253.3
lung331
lymph node290.9
ovary517.4
pancreas183.3
placenta301.2
prostate330.6
salivary gland328
skin256.8
small intestine277.2
spleen351
stomach304.2
testis337.8
thyroid gland304.9
urinary bladder308.5
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Disease
No.Disease DescriptionRef.
1(*605125, gene) Gaba-a receptor-associated protein; GABARAPOMIM


#424, YPRC/BPRC, Industry-University Research Center, Yonsei Univ., Seodaemun-gu, Seoul, Korea, 120-749
Tel: +82-2-2123-6626, Fax: +82-2-393-6589
2014-2019 (C) Yonsei Proteome Research Center