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> Protein (NX_O95199)
Protein (NX_O95199)
Protein
Gene SymbolRCBTB2 to neXtProt (NX_O95199)
DescriptionRCC1 and BTB domain-containing protein 2
Chromosome13
Location13q14.2 (49063095 ~ 49107369) to Ensembl
Sequene Features : Isoforms 2, Variants 75, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.positive regulation of GTPase activity .Ran guanyl-nucleotide exchange factor activity .N/A
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
2 75 0
2014-09-19protein level
2 55 0
2014-05-27transcript level
2 55 0
2014-02-25transcript level
2 55 0
2013-12-09transcript level
2 49 0
2013-11-01transcript level
2 46 0
2013-09-12transcript level
2 46 0
2013-08-17protein level
2 46 0
2013-07-15protein level
2 37 0
2013-06-11protein level
2 37 0
2013-02-12protein level
2 22 0
2012-12-20protein level
2 22 0
2012-10-30protein level
2 19 0
2012-10-07protein level
2 19 0
2012-08-24transcript level
2 13 0
2012-07-28transcript level
2 13 0
2012-06-08transcript level
2 13 0
2012-05-07transcript level
2 13 0
2012-04-10transcript level
2 13 0
2012-01-13transcript level
2 9 0
2011-12-20transcript level
2 9 0
2011-11-11transcript level
2 9 0
2011-08-23transcript level
2 9 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_O95199-1
1 18 1 60276.3712
NX_O95199-2
0 18 1 57732.1001
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-742404,EBI-2513774 FARS2  
  .gene expression
.tRNA processing
.phenylalanyl-tRNA aminoacylation
.tRNA aminoacylation for protein translation
.ATP binding
.phenylalanine-tRNA ligase activity
.magnesium ion binding
.tRNA binding
.mitochondrial matrix
.mitochondrion
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adipose tissue77
adrenal gland91
blood57
bone13
bone marrow41
brain77
cervix20
connective tissue40
ear186
embryonic tissue28
esophagus49
eye47
heart67
intestine17
kidney47
liver29
lung11
mammary gland6
mouth30
muscle18
nerve64
pancreas18
pituitary gland60
placenta31
prostate10
salivary gland49
skin9
spleen168
stomach20
testis55
thymus37
thyroid21
trachea38
uterus47
vascular58
Health State
TissuesTPM*
normal50
adrenal tumor79
breast (mammary gland) tumor10
chondrosarcoma12
colorectal tumor8
esophageal tumor57
germ cell tumor75
glioma18
head and neck tumor22
kidney tumor29
leukemia84
liver tumor10
non-neoplasia72
primitive neuroectodermal tumor of the CNS7
prostate cancer9
skin tumor15
uterine tumor22
Developmental Stage
TissuesTPM*
adult30
embryoid body14
blastocyst48
fetus86
juvenile35
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue12.4
adrenal gland11.8
appendix14.8
bone marrow3.3
cerebral cortex14
colon7
duodenum6
esophagus13.9
gallbladder15.1
heart muscle9.4
kidney16.3
liver5.7
lung10.4
lymph node12.1
ovary21.6
pancreas3
placenta14.7
prostate13.2
salivary gland18
skin4.2
small intestine5.9
spleen11.4
stomach7.9
testis8.2
thyroid gland33.7
urinary bladder14.7
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*603524, gene) Rcc1 domain- and btb domain-containing protein 2; RCBTB2OMIM


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