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> Protein (NX_O95237)
Protein (NX_O95237)
Protein
Gene SymbolLRAT to neXtProt (NX_O95237)
DescriptionLecithin retinol acyltransferase
Chromosome4
Location4q31.3 (155548097 ~ 155674270) to Ensembl
Sequene Features : Isoforms 1, Variants 40, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.retinoic acid metabolic process
.retinol metabolic process
.positive regulation of lipid transport
  + 4 more...
.phosphatidylcholine-retinol O-acyltransferase activity
.retinol binding
.transferase activity, transferring acyl groups
.retinoic acid binding
.perinuclear region of cytoplasm
.integral component of membrane
.rough endoplasmic reticulum
  + 2 more...
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 40 0
2014-09-19protein level
1 31 0
2014-05-27protein level
1 31 0
2014-02-25protein level
1 30 0
2013-12-09protein level
1 27 0
2013-11-01protein level
1 25 0
2013-09-12protein level
1 25 0
2013-08-17protein level
1 25 0
2013-07-15protein level
1 20 0
2013-06-11protein level
1 20 0
2013-02-12protein level
1 8 0
2012-12-20protein level
1 8 0
2012-10-30protein level
1 9 0
2012-10-07protein level
1 9 0
2012-08-24protein level
1 9 0
2012-07-28protein level
1 9 0
2012-06-08protein level
1 15 0
2012-05-07protein level
1 13 0
2012-04-10protein level
1 13 0
2012-01-13protein level
1 11 0
2011-12-20protein level
1 11 0
2011-11-11protein level
1 11 0
2011-08-23protein level
1 11 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_O95237-1
12 0 0 25686.3596
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
bone marrow20
brain1
ear62
embryonic tissue4
eye9
larynx42
liver4
mammary gland6
pancreas4
pituitary gland60
testis29
Health State
TissuesTPM*
normal5
germ cell tumor3
head and neck tumor7
leukemia10
non-neoplasia10
Developmental Stage
TissuesTPM*
adult4
fetus10
juvenile17
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
duodenum7.8
gallbladder6
liver5.2
small intestine7.2
testis3.6
thyroid gland4.4
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*604863, gene) Lecithin retinol acyltransferase; LRATOMIM
2(#613341, phenotype) Leber congenital amaurosis 14; LCA14OMIM


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