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> Protein (NX_O95295)
Protein (NX_O95295)
Protein
Gene SymbolSNAPIN to neXtProt (NX_O95295)
DescriptionSNARE-associated protein Snapin
Chromosome1
Location1q21.3 (153631130 ~ 153634306) to Ensembl
Sequene Features : Isoforms 1, Variants 8, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.positive regulation of late endosome to lysosome transport
.autophagic vacuole maturation
.terminal button organization
  + 14 more...
.SNARE binding .perinuclear region of cytoplasm
.synapse
.BLOC-1 complex
  + 9 more...
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 8 6
2014-09-19protein level
1 7 6
2014-05-27protein level
1 7 6
2014-02-25protein level
1 7 6
2013-12-09protein level
1 5 6
2013-11-01protein level
1 5 6
2013-09-12protein level
1 5 6
2013-08-17protein level
1 5 6
2013-07-15protein level
1 3 6
2013-06-11protein level
1 3 6
2013-02-12protein level
1 1 6
2012-12-20protein level
1 1 6
2012-10-30protein level
1 2 6
2012-10-07protein level
1 2 6
2012-08-24protein level
1 2 6
2012-07-28protein level
1 2 6
2012-06-08protein level
1 2 6
2012-05-07protein level
1 2 6
2012-04-10protein level
1 2 6
2012-01-13protein level
1 3 6
2011-12-20protein level
1 3 6
2011-11-11protein level
1 3 5
2011-08-23protein level
1 3 5
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_O95295-1
6 0 0 14864.8483
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-296723,EBI-2799016 DYSF  
  .vesicle fusion
.plasma membrane repair
.calcium-dependent phospholipid binding
.phospholipid binding
.calcium ion binding
.extracellular exosome
.sarcolemma
.cytoplasmic vesicle membrane
  + 8 more...
2 EBI-296723,EBI-514908 SPTB  
  .actin filament capping
.hemopoiesis
.axon guidance
  + 2 more...
.actin filament binding
.ankyrin binding
.structural constituent of cytoskeleton
.actin binding
.protein complex
.intrinsic component of the cytoplasmic side of the plasma membrane
.actin cytoskeleton
  + 5 more...
3 EBI-296723,EBI-1633392 SLC14A2  
  .transmembrane transport
.urea transport
.cell adhesion molecule binding
.urea transmembrane transporter activity
.apical plasma membrane
.integral component of membrane
.membrane
.plasma membrane
4 EBI-296723,EBI-5323863 LRRK2  
  .negative regulation of peroxidase activity
.regulation of synaptic vesicle exocytosis
.regulation of branching morphogenesis of a nerve
  + 64 more...
.protein kinase A binding
.ion channel binding
.protein homodimerization activity
  + 18 more...
.extracellular exosome
.membrane raft
.perikaryon
  + 25 more...
5 EBI-296723,EBI-465872 BLOC1S2  
  .mitochondrial outer membrane permeabilization
.platelet dense granule organization
.anterograde synaptic vesicle transport
  + 8 more...
.gamma-tubulin binding
.protein C-terminus binding
.recycling endosome
.BLOC-1 complex
.centrosome
  + 3 more...
6 EBI-296723,EBI-465804 DTNBP1  
  .membrane organization
.regulation of dopamine receptor signaling pathway
.platelet dense granule organization
  + 11 more...
.N/A .postsynaptic membrane
.dendritic spine
.neuron projection
  + 14 more...
7 EBI-296723,EBI-465781 BLOC1S6  
  .membrane fusion
.membrane organization
.positive regulation of pigment cell differentiation
  + 12 more...
.actin filament binding
.protein homodimerization activity
.identical protein binding
.syntaxin binding
.BLOC-1 complex
.transport vesicle
.extrinsic component of membrane
  + 4 more...
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adipose tissue77
ascites25
bladder33
blood16
bone111
bone marrow20
brain42
cervix61
connective tissue33
embryonic tissue28
eye105
heart89
intestine30
kidney28
liver19
lung98
lymph383
lymph node33
mammary gland19
muscle75
ovary78
pancreas56
parathyroid97
placenta49
prostate89
salivary gland98
skin99
stomach10
testis13
tonsil117
uterus51
vascular19
Health State
TissuesTPM*
normal31
breast (mammary gland) tumor32
cervical tumor86
chondrosarcoma132
colorectal tumor17
gastrointestinal tumor16
germ cell tumor53
glioma74
head and neck tumor14
kidney tumor29
leukemia21
liver tumor31
lung tumor136
lymphoma235
non-neoplasia10
ovarian tumor105
pancreatic tumor95
primitive neuroectodermal tumor of the CNS47
prostate cancer115
skin tumor119
soft tissue/muscle tissue tumor95
uterine tumor77
Developmental Stage
TissuesTPM*
adult45
embryoid body14
blastocyst16
fetus35
juvenile17
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue30.1
adrenal gland30
appendix22.1
bone marrow9.5
cerebral cortex21.9
colon20.8
duodenum13.5
esophagus28.2
gallbladder24.4
heart muscle46.3
kidney24.7
liver15.4
lung22.4
lymph node29.5
ovary27.7
pancreas8.3
placenta20.3
prostate26.8
salivary gland16.6
skin20.6
small intestine15.8
spleen24.5
stomach17.2
testis22
thyroid gland28.1
urinary bladder32.1
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*607007, gene) Snare-associated protein snapin; SNAPAPOMIM


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